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Consumo di sostanze psicoattive in campioni della popolazione scolastica guatemalteca
È stata condotta una ricerca composta da 4 lavori di laurea magistrale, con metodologia descrittiva mista, che affrontano i diversi fattori di rischio che causano gli studenti in Guatemala, che cadono in problemi di uso, consumo e abuso di...
Il profilo trascrizionale della microglia nel disturbo depressivo maggiore mostra l'inibizione della microglia corticale della materia grigia
Astratto
Sfondo
Le microglia sono state implicate nella fisiopatologia del disturbo depressivo maggiore (MDD), ma le informazioni sui meccanismi biologici sono limitate. Pertanto, abbiamo studiato il profilo di espressione genica...
Nursing training and its association with burnout syndrome among Mexican undergraduate students
Abstract:
Introduction. Previous data suggest that healthcare students, such as nursing students, might have a differential risk of presenting burnout syndrome caused by the stress they are subjected to. However, the evidence is still...
Mental illness attitudes in medical education: Assessing the stigma in medical students
Abstract:
Introduction. Factors affecting the quality of physician care include a shortage of trained staff, stigma, and discrimination.
Objective. The objective was to compare the intensity of stigmatization before and after a Psychiatry...
Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention
Abstract
Substance use disorders (SUDs) are highly prevalent and impact individuals' health, well-being, and social functioning. Long-lasting changes in brain networks involved in reward, executive function, stress reactivity, mood, and...
Effectiveness evaluation of online Mindfulness in mental health and alcohol consumption in medical students during the COVID-19 pandemic
Abstract:
Introduction. As a result of the COVID-19 pandemic, the prevalence of stress, anxiety, depression, and alcohol consumption has increased among medical students. Mindfulness is an intervention to decrease these psychopathologies...
Assessment of Medical Cannabis and Health-Related Quality of Life
Abstract
Importance The use of cannabis as a medicine is becoming increasingly prevalent. Given the diverse range of conditions being treated with medical cannabis, as well as the vast array of products and dose forms available...
SMART recovery for youth: un piccolo studio qualitativo esplorativo che esamina il potenziale di un programma di cambiamento comportamentale di mutuo soccorso e sostegno tra pari per i giovani
Astratto
Sfondo
SMART (Self-Management and Recovery Training) Recovery è un programma di mutuo soccorso informato dalla terapia cognitivo-comportamentale e dal colloquio motivazionale che fornisce supporto per una serie di...
La prevención de la conducta suicida en adolescentes en el ámbito escolar: una revisión sistemática
Resumen
Antecedentes: El suicido representa un grave problema de salud pública en el mundo, siendo actualmente la segunda causa de muerte en jóvenes con edades comprendidas entre los 15 y los 29 años. Objetivo: El propósito de la...
Buprenorphine versus methadone for the treatment of opioid dependence
Summary
Background
Opioid dependence is associated with substantial health and social burdens, and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for people who receive this treatment. Methadone and...
Economic Evaluations of Pharmacologic Treatment for Opioid Use Disorder: A Systematic Literature Review
Abstract
Objective
The crisis of opioid use puts a strain on resources in the United States and worldwide. There are 3 US Food and Drug Administration–approved medications for treatment of opioid use disorder: methadone, buprenorphine...
Focal mu-opioid receptor activation promotes neuroinflammation and microglial activation in the mesocorticolimbic system: Alterations induced by inflammatory pain
Abstract
Microglia participates in the modulation of pain signaling. The activation of microglia is suggested to play an important role in affective disorders that are related to a dysfunction of the mesocorticolimbic system (MCLS) and...
Implementation and workflow strategies for integrating digital therapeutics for alcohol use disorders into primary care: a qualitative study
Abstract
Background
Alcohol use disorders (AUD) are prevalent and often go untreated. Patients are commonly screened for AUD in primary care, but existing treatment programs are failing to meet demand. Digital therapeutics include...
Buprenorphine versus methadone for the treatment of opioid dependence: a systematic review and meta-analysis of randomised and observational studies
Opioid dependence is associated with substantial health and social burdens, and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for people who receive this treatment. Methadone and buprenorphine are common...
Comparison of Treatments for Cocaine Use Disorder Among Adults
Key Points
Question What treatments for cocaine use disorder are associated with objective reductions in cocaine use among adults?
Findings In this meta-analysis of 157 clinical trials comprising 402 treatment groups and 15 842...
Cocaine Reading List
Cocaine is an addictive stimulant drug that originates from the leaves of the coca plant, which is indigenous to South America. The drug's effects include heightened alertness, attention, and energy, as well as feelings of euphoria and...
Exploring the link between cannabis use and future substance use in younger adults
Abstract
Introduction
Young adults report high rates of current cannabis use. The increase of legalised cannabis in the United States has led to greater access and availability, causing cannabis to become the new “gateway” drug. This...
Esplorare le barriere terapeutiche sull'uso di metanfetamina in cristalli tra i giovani in Zimbabwe
L'abuso di sostanze tra i giovani è una delle maggiori preoccupazioni pubbliche nella salute globale. Questo studio si proponeva di esplorare le barriere terapeutiche tra i giovani in Zimbabwe.
I dati sono stati raccolti attraverso...
Ingestione di sostanze illecite da parte di bambini nella prima infanzia prima e durante la pandemia di COVID-19
Astratto
Importanza Le informazioni sull'andamento dell'ingestione di sostanze illecite tra i bambini piccoli durante la pandemia sono limitate.
Obiettivi Valutare i cambiamenti immediati e duraturi nei tassi complessivi di...
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