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Psychoactive Substances
Psychoactive substances are natural or synthetic substances that act on the central nervous system and alter mental processes such as mood, perception, cognition, consciousness, and behaviour. These substances may be legally prescribed medications (e.g., pain medications or sedatives), legally available substances such as alcohol or caffeine, or controlled or illicit drugs. Psychoactive substances can be used for medical, social, cultural, or recreational purposes, but some carry risks of misuse, dependence, and health or social harms when used in harmful ways.
Comprendere i rischi della miscelazione di droghe
17 febbraio 2022
La miscelazione di droghe, nota anche come uso di polisostanze, si verifica quando due o più farmaci vengono assunti insieme o entro un breve periodo di tempo, intenzionalmente o meno. Anche se qualcuno ha mescolato droghe...
Polysubstance Use Facts
What is polysubstance use?
The use of more than one drug, also known as polysubstance use, is common. This includes when two or more are taken together or within a short time period, either intentionally or unintentionally.
Intentional...
FDA Approves New Buprenorphine Treatment Option for Opioid Use Disorder
For Immediate Release: May 23, 2023
Today, the U.S. Food and Drug Administration approved Brixadi (buprenorphine) extended-release injection for subcutaneous use (under the skin) to treat moderate to severe opioid use disorder (OUD)...
Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention
Abstract
Substance use disorders (SUDs) are highly prevalent and impact individuals' health, well-being, and social functioning. Long-lasting changes in brain networks involved in reward, executive function, stress reactivity, mood, and...
Strategies to Address Cocaine and Methamphetamine
Presented by Richard Rawson, PhD, Emeritus Professor in the Department of Psychiatry and Biobehavioral Science, UCLA School of Medicine and a Research Professor at the University of Vermont, this presentation provided an overview of the...
UNODC supported delegations from four Central Asian countries in a high-level study tour to the United Kingdom
The UNODC Regional Office for Central Asia (ROCA) together with the UNODC Prevention, Treatment and Rehabilitation Section (PTRS) organized a study tour for high-level representatives, including senior officials, policymakers and substance...
72º Regular Session of the Inter-American Drug Abuse Control Comission was held
In the magazine CIJ Informa, the participation of CIJ, host chapter institution of ISSUP Mexico, in the 71st Regular Session of CICAD is reviewed.
The Anti-Stigma Network
The Anti-Stigma Network has been launched!
The Mission
The Anti-Stigma Network has been created by a group of organisations coming together with a shared mission.
Collectively they aim to improve understanding of the stigma and...
Buprenorphine versus methadone for the treatment of opioid dependence
Summary
Background
Opioid dependence is associated with substantial health and social burdens, and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for people who receive this treatment. Methadone and...
Economic Evaluations of Pharmacologic Treatment for Opioid Use Disorder: A Systematic Literature Review
Abstract
Objective
The crisis of opioid use puts a strain on resources in the United States and worldwide. There are 3 US Food and Drug Administration–approved medications for treatment of opioid use disorder: methadone, buprenorphine...
Comparison of Treatments for Cocaine Use Disorder Among Adults
Key Points
Question What treatments for cocaine use disorder are associated with objective reductions in cocaine use among adults?
Findings In this meta-analysis of 157 clinical trials comprising 402 treatment groups and 15 842...
Cocaine Reading List
Cocaine is an addictive stimulant drug that originates from the leaves of the coca plant, which is indigenous to South America. The drug's effects include heightened alertness, attention, and energy, as well as feelings of euphoria and...
Esaidrocannabinolo (HHC) e sostanze correlate
Introduzione
I mercati dell'esaidrocannabinolo (HHC) e dei cannabinoidi semi-sintetici correlati (SSC) sono aree in rapida evoluzione con informazioni relativamente limitate attualmente disponibili.
La situazione europea presentata nella...
Risposta all'uso di stimolanti: sviluppi nel trattamento
Obiettivo: Comprendere meglio gli attuali sviluppi nel trattamento dell'uso di stimolanti.
Le droghe stimolanti sono seconde solo alla cannabis come classe di droghe illecite più utilizzate a livello globale, rappresentando 68 milioni...
Esplorare le barriere terapeutiche sull'uso di metanfetamina in cristalli tra i giovani in Zimbabwe
L'abuso di sostanze tra i giovani è una delle maggiori preoccupazioni pubbliche nella salute globale. Questo studio si proponeva di esplorare le barriere terapeutiche tra i giovani in Zimbabwe.
I dati sono stati raccolti attraverso...
2022-2023 Medical Council on Alcohol (MCA) Legacy Essay Competition
It has been widely reported that youth alcohol consumption has decreased over recent years. What is the evidence to support this view? What are the implications for alcohol related health harm, promotion of safe drinking and health policy?
...
Tendenze nell'overdose e in altri decessi indotti da droghe in Australia
Questo rapporto presenta i dati più recenti e approfonditi sulle morti per overdose e indotte da droghe in Australia, che coprono il periodo dal 2002 al 2021. Si tratta del prodotto più recente di una serie di pubblicazioni annuali sulle...
Implementing PLAT in Sri Lanka
Psychoactive substance use and substance use disorders (SUDs) remain to be a major problem around the world. Which has a negative effect on global health and social and economic functioning. When we are paying attention to the most...
Esposizione precoce alla Cannabis e sue conseguenze a lungo termine nel cervello
ISSUP Italia vi invita a partecipare al loro prossimo webinar su Come l'esposizione precoce alla cannabis modella il cervello ed esercita effetti a lungo termine.
Normalizzazione dei principi e delle pratiche di prevenzione per ridurre i disturbi da uso di sostanze attraverso un quadro integrato di diffusione e attuazione
Negli ultimi 30 anni, le principali scoperte della ricerca nel campo della prevenzione dell'uso di sostanze sono servite a:
1) migliorare la comprensione degli effetti farmacologici sul sistema nervoso e delle conseguenze sanitarie e...