Source: Darpö, B., Pirner, M., Longstreth, J., & Ferber, G. (2019). Effect of lofexidine on cardiac repolarization during treatment of opioid withdrawal. Drug and alcohol dependence, 205, 107596. Highlights Small mean QTcF increases were observed with lofexidine (<8 ms) on Days 1–2. QTcF mean...

Source: Dietze P, Jauncey M, Salmon A, et al. Effect of Intranasal vs Intramuscular Naloxone on Opioid Overdose: A Randomized Clinical Trial. JAMA Netw Open. 2019;2(11):e1914977. doi: https://doi.org/10.1001/jamanetworkopen.2019.14977 Key Points Question Is 800 μg of naloxone hydrochloride...

Source: CMAJ Open 2019. DOI:10.9778/cmajo.20190026 Abstract Background: Rates of cannabis use among patients receiving methadone maintenance therapy are high, and cannabis use may be associated with outcomes of methadone maintenance therapy. We examined the effect of cannabis use on opioid use in...

Source: Dietze P, Jauncey M, Salmon A, et al. Effect of Intranasal vs Intramuscular Naloxone on Opioid Overdose: A Randomized Clinical Trial. JAMA Netw Open. 2019;2(11):e1914977. doi: https://doi.org/10.1001/jamanetworkopen.2019.14977 Key Points Question Is 800 μg of naloxone hydrochloride...

Source: Hall, O. T., Hall, O. E., McGrath, R. P., & Haile, Z. T. (2019). Years of Life Lost due to Opioid Overdose in Ohio: Temporal and Geographic Patterns of Excess Mortality. Journal of addiction medicine. Abstract Objectives: The aim of the study was to quantify the burden of premature mortality...

Source: Zhong, B. L., Xu, Y. M., Xie, W. X., Lu, J., Yu, W. B., & Yan, J. (2019). Alcohol drinking in Chinese methadone-maintained clients: a self-medication for depression and anxiety?. Journal of addiction medicine, 13(4), 314-321. Abstract Objectives: Unhealthy alcohol use is associated with...

Source: Bedene A, Lijfering WM, Niesters M, et al. Opioid Prescription Patterns and Risk Factors Associated With Opioid Use in the Netherlands. JAMA Netw Open. Published online August 28, 20192(8):e1910223. doi:10.1001/jamanetworkopen.2019.10223 KEY POINTS Question Are the prevalence of opioid...

This guide focuses on using medication-assisted treatment for opioid use disorder in jails and prisons and during the reentry process when justice -involved persons return to the community. It provides an overview of policies and evidence-based practices that reduce the risk of overdose and relapse.

Source: Gicquelais et al. Harm Reduction Journal (2019) 16:46 https://doi.org/10.1186/s12954-019-0317-3 Abstract Background Persons in addiction treatment are likely to experience and/or witness drug overdoses following treatment and thus could benefit from overdose education and naloxone...

Source: https://www.asam.org/docs/default-source/quality-science/a-drug-court-clinician's-guide-for-linking-people-to-opioid-treatment-services.pdf Introduction This pocket guide is designed to help counselors and therapists working with drug court participants refer and link participants to opioid...

Source: Godersky et al. Addict Sci Clin Pract (2019) 14:11 https://doi.org/10.1186/s13722-019-0139-3 Abstract Background Buprenorphine effectively reduces opioid craving and illicit opioid use. However, some patients may not take their medication as prescribed and thus experience suboptimal outcomes...

The opioid epidemic has significantly penetrated the criminal justice (CJ) system. This brief provides guidance to state governments on increasing the availability of evidence-based MAT in CJ settings. By including the CJ system as a path to treatment, states may see an increase in access to, and...

This Clinical Guide provides comprehensive, national guidance for optimal management of pregnant and parenting women with opioid use disorder and their infants. The Clinical Guide helps healthcare professionals and patients determine the most clinically appropriate action for a particular situation...

A pesar de que en México está disponible en tratamiento con metadona, se requieren esfuerzos para ampliar su uso. Si bien algunas instituciones como Centros de Integración Juvenil, A.C. (CIJ) cuentan con protocolos de tratamiento establecidos y manuales de procedimientos claros, no sucede así en...