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Trends in Alcohol-Related Deaths by Sex in the US, 1999-2020
Abstract
Importance Alcohol consumption rates have been increasing among women in the US, which may affect mortality rates and sex gaps. Therefore, conducting a comprehensive assessment of sex differences in alcohol-related deaths is...
Self-reported Xylazine Experiences: A Mixed-methods Study of Reddit Subscribers
Abstract
Objectives
Xylazine is an α2-agonist increasingly prevalent in the illicit drug supply. Our objectives were to curate information about xylazine through social media from people who use drugs (PWUDs). Specifically, we sought...
Implementation and workflow strategies for integrating digital therapeutics for alcohol use disorders into primary care: a qualitative study
Abstract
Background
Alcohol use disorders (AUD) are prevalent and often go untreated. Patients are commonly screened for AUD in primary care, but existing treatment programs are failing to meet demand. Digital therapeutics include...
Nationally representative surveys on cannabis use lack product details relevant to public health
Abstract
Objectives
Many annual, nationally representative US surveys that assess cannabis use do not collect information on product characteristics despite varying health risks and benefits. Capitalizing on a rich dataset of...
Disruptions to U.S. local public health’s role in population-based substance use prevention and response during COVID-19
Background
COVID-19 dramatically limited the scale and scope of local health department (LHD) work, redirecting resources to the response. However, the need for essential public health services—including substance use prevention—was not...
Disruptions to U.S. local public health’s role in population-based substance use prevention and response during COVID-19
Background
The COVID-19 emergency has tested the public health, medical, and public safety infrastructure of the United States (U.S.) in unprecedented ways. As the focal point for public health in their communities, local health...
Improving equity and access to buprenorphine treatment through telemedicine at syringe services programs
Background
In the United States, access to buprenorphine remains low and disparities regarding who receives treatment have emerged. Federal laws have regulated buprenorphine delivery, ultimately limiting its implementation more broadly...
Variations in national availability of waivered buprenorphine prescribers by racial and ethnic composition of zip codes
Background
Opioid overdose remains a public health crisis in diverse communities. Between 2019 and 2020, there was an almost 40% increase in drug fatalities primarily due to opioid analogues of both stimulants and opioids. Medications...
Is fetal brain monoamine oxidase inhibition the missing link between maternal smoking and conduct disorders?
Abstract
Smoking is the leading cause of preventable illness in the world today. Prenatal cigarette smoke exposure (PCSE) is a particularly insidious form because so many of its associated health effects befall the unborn child and...
Simultaneous Alcohol and Marijuana Use Among Young Adults: A Scoping Review of Prevalence, Patterns, Psychosocial Correlates, and Consequences
ABSTRACT
BACKGROUND: Alcohol and marijuana are commonly used by young adults, and use of both substances, particularly at the same time, is prevalent among this population. Understanding the prevalence, patterns, correlates, and...
Fetal Exposure to Cannabis and Childhood Metabolic Outcomes: The Healthy Start Study
Abstract
Objective
To assess the impact of fetal exposure to cannabis on adiposity and glucose-insulin traits in early life.
Research Design and Methods
We leveraged a subsample of 103 mother-child pairs from Healthy Start, an...
Severe bacterial infections in people who inject drugs: The role of injection-related tissue damage
Abstract
Background
In the context of the current U.S. injection drug use epidemic, targeted public health harm reduction strategies have traditionally focused on overdose prevention and reducing transmission of blood-borne viral...
Effect of Combination Treatment With Varenicline and Nicotine Patch on Smoking Cessation Among Smokers Who Drink Heavily A Randomized Clinical Trial
Abstract
Importance The concurrent use of both tobacco and alcohol causes substantial disease and early mortality, and smokers who drink heavily tend to be less successful in smoking cessation than smokers who do not. Although...
Risk of Opioid Overdose Associated With Concomitant Use of Oxycodone and Selective Serotonin Reuptake Inhibitors
Abstract
Importance Some selective serotonin reuptake inhibitors (SSRIs) inhibit the enzymes responsible for the metabolism of oxycodone, a potent prescription opioid. The clinical consequences of this interaction on the risk of opioid...
HealthCare educational differences in pain management, adverse childhood experiences and their relationship to substance use disorder education
The Ohio Attorney General selected experts from a number of academic fields to the Scientific Committee on Opioid Prevention and Education (SCOPE) to help the State of Ohio in tackling the opioid crisis in the United States. The focus of...
Trends in healthcare expenditures and resource utilization among a nationally representative population with opioids in the United States: a serial cross-sectional study, 2008 to 2017
One of the most serious public health concerns in recent decades has been the opioid epidemic in the United States (US). Over 9.9 million Americans aged 12 and up abused prescription pain drugs in 2018, and roughly 2 million Americans were...
High-dose buprenorphine induction in the emergency department for treatment of opioid use disorder
In response to the rising efficacy of the illicit opioid drug supply and often observed delays in access to follow-up therapy, emergency departments (EDs) occasionally utilize a high-dose buprenorphine induction method for the treatment of...
Is telemedicine the answer to rural expansion of medication treatment for opioid use disorder? Early experiences in the feasibility study phase of a National Drug Abuse Treatment Clinical Trials Network Trial
Abstract
Telemedicine (TM) enabled by digital health technologies to provide medical services has been considered a key solution to increasing health care access in rural communities. With the immediate need for remote care due to the...
The rapidly changing composition of the global street drug supply and Its effects on high-risk groups for COVID-19
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