An overdose occurs when an individual consumes a drug, or a combination of substances, in a quantity large enough to cause acute toxic effects, life-threatening reactions, or death. The severity of an overdose depends on factors such as the type of drug, dose, method of use, the individual’s tolerance, and their physical condition.
Overdoses may result in transient effects (such as confusion, nausea, or respiratory depression) or permanent harm, including brain injury or fatality. The lethal dose of a drug varies widely between individuals and circumstances.
Prompt medical intervention is critical, as many overdoses, especially opioid-related ones, can be reversed through the timely administration of medications like naloxone.