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Abstract

Background

Tobacco addiction is a complex, multicomponent phenomenon stemming from nicotine’s pharmacology and the user’s biology, psychology, sociology, and environment. After decades of public denial, the tobacco industry now...

Abstract

Background

Opioid-related overdose deaths have risen sharply among young adults. Despite this increase, access to evidence-based medication for opioid agonist treatment (OAT) for youth remains low. Among older adults, barriers to...

Abstract

Novel molecular targets are needed to develop new medications for the treatment of cocaine addiction. Here we investigated a role for glucagon-like peptide-1 (GLP-1) receptors in the reinstatement of cocaine-seeking behavior, an...

Conclusions of this study indicate that enacting a regulation to lower the nicotine content of cigarettes to minimally addictive levels in the United States would lead to a substantial reduction in tobacco-related mortality, despite...

Astratto

Le sigarette sono state fortemente associate al successivo uso di marijuana tra gli adolescenti, ma le sigarette elettroniche (sigarette elettroniche) stanno ora rapidamente sostituendo le sigarette tradizionali tra i giovani...

ABSTRACT

Objectives: Previous studies have found a negative population-level correlation between medical marijuana availability in US states, and trends in medical and nonmedical prescription drug use. These studies have been interpreted...

ABSTRACT

Background: On December 6 and 7, 2017, the US Department of Health and Human Services (HHS) hosted its first Code-a-Thon event aimed at leveraging technology and data-driven solutions to help combat the opioid epidemic. The...

Novel psychoactive substances (NPS) refer to synthetic compounds or derivatives of more widely known substances of abuse that have emerged over the last two decades. Case reports suggest that users combine substances to achieve desired...

Abstract

Addiction is a complex phenomenon characterized by a loss of control and compulsive, habitual behavior. Since there is no single, specific cause for addiction, there is no single, standard treatment for it. A variety of approaches...

Astratto

Abbiamo esaminato la prevalenza e i predittori di regole domestiche complete senza fumo (cioè case e auto senza fumo) tra fumatori e non fumatori in Minnesota. I dati provengono dal Minnesota Adult Tobacco Survey del 2014; le...

Astratto

Sfondo

Si ipotizza che i cicli di alcol e stress contribuiscano ai disturbi da uso di alcol. Il modo in cui ciò avviene è poco compreso, anche se sia l'alcol che lo stress attivano il sistema neuroimmunitario, le molecole...

Abstract

Diverse nicotine replacement therapy options may improve consumer usage. This study was conducted to establish the bioequivalence of a new cherry‐flavored mini lozenge with that of a currently marketed mint‐flavored mini lozenge...

Astratto

I progressi contemporanei nelle neuroscienze delle dipendenze hanno accompagnato il crescente interesse per l'antica pratica di allenamento mentale della meditazione di consapevolezza come potenziale terapia per la dipendenza...

Summary

What is already known about this topic?

Eight states, including Colorado, have legalized recreational marijuana use among persons aged ≥21 years. The association between marijuana use and occupational injury is of public health...

Abstract

Alcohol consumption is responsible for 3.3 million deaths globally or nearly 6% of all deaths. Alcohol use contributes to both communicable and noncommunicable diseases, as well as violence and injuries. The purpose of this review...

Abstract

Background

Alcohol and drug use are leading causes of morbidity and mortality that frequently go unidentified in medical settings. As part of a multi-phase study to implement electronic health record-integrated substance use...

Astratto

Il fumo di sigaretta materno durante la gravidanza rimane una delle cause più comuni e prevenibili di restrizione della crescita fetale (FGR), una condizione in cui un feto non è in grado di raggiungere le sue dimensioni...