Hledat

Abstract

Objectives: Our study aimed to evaluate the effectiveness of general practitioners’ (GPs’) smoking cessation support (SCS).

Study design: We carried out a cross-sectional study between February and April 2016.

Setting and...

Cigarette smoking damages just about every organ in the body and reduces overall health. Even with the prevalence of accessible nicotine replacement therapies and behavioral counseling, there remains a need for alternative therapies to...

Adenosine receptors (AR) are a family of G-protein coupled receptors, comprised of four members, named A1, A2A, A2B, and A3 receptors, found widely distributed in almost all human body tissues and organs. To date, they are known to...

Yanhui Liao

Introduction: Chronic use of both Ketamine (“K powder”) and methamphetamine (MA, “ice”) can induce psychiatric symptoms. This study aimed at exploring drug-induced psychiatric symptoms in chronic ketamine users and MA users.

Odůvodnění

Cílem tohoto pokynu je zlepšit kvalitu péče a výsledků léčby u pacientů s poruchou užívání alkoholu (AUD), jak je definována v DSM-5 (Americká psychiatrická asociace 2013). Pokyny se zaměřují konkrétně na farmakologickou léčbu...

Inclusion Health is a framework for action that helps find ways of improving the health and well-being for socially excluded groups. These populations, who have in common adverse life experiences and risk factors, such as poverty and...

In 2013 nalmefene was authorised for moderating drinking among patients not in need of detoxification, extending pharmacotherapy to less dependent drinkers. Though uniquely authorised for this purpose, this review found other (and probably...

SUMMARY

Drug addiction is one of the most important health problems worldwide. This pathology results in the death of about 500,000 individuals annually around the globe. Despite this scenario, the development of effective drug therapies...

This interactive game lets you look into the brain of mice under the influence of different drugs. You can study the different brain mechanisms that are triggered with various common illicit substances. 

Abstraktní

Nedávné studie na zvířatech ukazují, že nutkavé vyhledávání kokainu silně snižuje aktivitu prelimbické frontální kůry, zatímco optogenetická stimulace této oblasti mozku významně inhibuje nutkavé vyhledávání kokainu, což...

ABSTRACT

Opioid use in pregnancy has escalated dramatically in recent years, paralleling the epidemic observed in the general population. To combat the opioid epidemic, all health care providers need to take an active role. Pregnancy...

The abuse of novel psychoactive substances (NPS) has been increasing dramatically worldwide since late 2000s. By the end of 2015, more than 560 NPS had been reported to the European Monitoring Centre for Drugs and Drug Addiction. Although...

ABSTRACT

Background: The new psychoactive drugs (NPD) are those that represent a danger to public health and are not prohibited by conventions on international narcotics. The concept also includes new contexts and new routes of consumption...

Abstraktní

Kokain uplatňuje své behaviorální stimulační účinky tím, že usnadňuje synaptické působení neurotransmiterů, jako je dopamin a serotonin. Je také neurotoxický a široce cytotoxický, což vede k úmrtím na předávkování. Ukazujeme, že...

A new study published in the journal Biological Psychiatry claims that one’s desire for cocaine may be reduced by blocking signalling from a specific system in the brain primarily responsible for promoting wakefulness and appetite.

The...

Alcohol use is highly prevalent globally with numerous negative consequences to human health, including HIV progression, in people living with HIV (PLH). The HIV continuum of care, or treatment cascade, represents a sequence of targets for...

As we welcome in the New Year it seems an ideal time to take stock and present the key points from the 2016 European Drug Report (EDR), the European Monitoring Centre for Drug and Addiction’s (EMCDDA) annual review of the European drug...