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Higher doses of buprenorphine may improve treatment outcomes for people with opioid use disorder
A study funded by the NIH found that adults with opioid use disorder (OUD) who take higher doses of buprenorphine, an opioid addiction treatment medication, have a lower risk of emergency department or inpatient visits related to behavioral...
Trauma exposure across the lifespan among individuals engaged in treatment with medication for opioid use disorder: differences by gender, PTSD status, and chronic pain
Background: Limited research has been conducted on lifetime trauma exposure among individuals undergoing medication treatment for opioid use disorder (MOUD). A multisite study provided an opportunity to investigate the prevalence of...
Stigmatizing imagery for substance use disorders: a qualitative exploration
Synthetic Opioids: Navigating a Changing Landscape in the Treatment of Opioid Use Disorder
Integrating Opioid Use Disorder Treatment Into Primary Care Settings
Abstract
Importance Medication for opioid use disorder (MOUD) (eg, buprenorphine and naltrexone) can be offered in primary care, but barriers to implementation exist.
Objective To evaluate an implementation intervention over 2 years to...
Use of Medication for Opioid Use Disorder Among Adults With Past-Year Opioid Use Disorder in the US, 2021
Discussion
Despite guidelines recommending MOUD, approximately 1 in 5 adults with past-year OUD received any MOUD. Furthermore, some groups were substantially less likely to receive MOUD, in particular Black adults, women, those unemployed...
Stress, Coping, and Context: Examining Substance Use Among LGBTQ Young Adults With Probable Substance Use Disorders
In this research, the authors explored how lesbian, gay, bisexual, transgender, and queer (LGBTQ) young adults with problematic substance use made sense of their substance use in relation to their LGBTQ identities.
The authors interviewed...
Implementation and workflow strategies for integrating digital therapeutics for alcohol use disorders into primary care: a qualitative study
Abstract
Background
Alcohol use disorders (AUD) are prevalent and often go untreated. Patients are commonly screened for AUD in primary care, but existing treatment programs are failing to meet demand. Digital therapeutics include novel...
Faktor-faktor yang terkait dengan penggunaan zat, pengobatan, kehadiran setelah pemulihan sebaya, intervensi pelatih di unit gawat darurat
Abstrak
Perkenalan
Intervensi singkat dengan dukungan pelatih pemulihan sebaya telah digunakan untuk menghasilkan rujukan ke perawatan gangguan penggunaan zat dari departemen darurat (ED). Studi retrospektif ini mengevaluasi faktor-faktor...
Sikap guru terhadap praktik berbasis bukti: Analisis eksplorasi dan konfirmasi dari skala sikap praktik berbasis bukti yang disesuaikan dengan sekolah
Abstrak
Latar
Skala Sikap Praktik Berbasis Bukti (EBPAS) banyak digunakan dalam penelitian implementasi, tetapi belum diadaptasi dan divalidasi untuk digunakan di kalangan guru pendidikan umum, yang paling mungkin memberikan program...
Gangguan terhadap peran kesehatan masyarakat lokal AS dalam pencegahan dan respons penggunaan zat berbasis populasi selama COVID-19
Latar
COVID-19 secara dramatis membatasi skala dan ruang lingkup pekerjaan departemen kesehatan setempat (LHD), mengarahkan sumber daya ke respons. Namun, kebutuhan akan layanan kesehatan masyarakat yang penting — termasuk pencegahan...
Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure
Abstract
Adolescent binge drinking is a major risk factor for psychiatric disorders later in life including alcohol use disorder. Adolescent alcohol exposure induces epigenetic reprogramming at the enhancer region of the activity-regulated...
Patterns of Health Care Use 5 Years After an Intervention Linking Patients in Addiction Treatment With a Primary Care Practitioner
Abstract
Importance Substance use disorders are associated with high rates of emergency department (ED) use and challenges engaging with primary care services.
Objective To examine 5-year health care engagement and utilization outcomes...
Respiratory events associated with concomitant opioid and sedative use among Medicare beneficiaries with chronic obstructive pulmonary disease
Abstract
Background Opioids and sedatives are commonly prescribed in chronic obstructive pulmonary disease (COPD) patients for symptoms of dyspnoea, pain, insomnia, depression and anxiety. Older adults are advised to avoid these...
Involvement of the ghrelin system in the maintenance and reinstatement of cocaine-motivated behaviors: a role of adrenergic action at peripheral β1 receptors
Abstract
Cocaine addiction is a significant medical and public concern. Despite decades of research effort, development of pharmacotherapy for cocaine use disorder remains largely unsuccessful. This may be partially due to insufficient...
Bupropion and Naltrexone in Methamphetamine Use Disorder
Abstract
Background
The use of naltrexone plus bupropion to treat methamphetamine use disorder has not been well studied.
Methods
We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the use of a...
Trends in Cannabis Polysubstance Use During Early Pregnancy Among Patients in a Large Health Care System in Northern California
Abstract
Importance Rates of prenatal cannabis use are increasing alongside perceptions that cannabis is a harmless therapeutic for pregnancy-related ailments, while rates of prenatal use of alcohol and tobacco are decreasing. It is...
Variations in national availability of waivered buprenorphine prescribers by racial and ethnic composition of zip codes
Background
Opioid overdose remains a public health crisis in diverse communities. Between 2019 and 2020, there was an almost 40% increase in drug fatalities primarily due to opioid analogues of both stimulants and opioids. Medications for...
Intentions and Attempts to Quit Smoking Among Sexual Minoritized Adult Smokers After Exposure to the Tips From Former Smokers Campaign
Abstract
Importance Significant disparities exist in smoking behaviors by sexual minority status in the US.
Objective To examine potential differences in the associations between exposure to the Tips From Former Smokers (Tips) campaign...
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