Kokain uplatňuje své behaviorální stimulační účinky tím, že usnadňuje synaptické působení neurotransmiterů, jako je dopamin a serotonin. Je také neurotoxický a široce cytotoxický, což vede k úmrtím na předávkování. Ukazujeme, že...
Working with mice, researchers at Johns Hopkins have contributed significant new evidence to support the idea that high doses of cocaine kill brain cells by triggering overactive autophagy, a process in which cells literally digest their...
Background and aims: There is increasing research evidence about the causal role of alcohol in cancer, accompanied by unclear and conflicting messages in the media. This paper aimed to clarify the strength of the evidence for alcohol as a...
This is one of 25 cells in the Alcohol Treatment Matrix. The cell discusses key research relating to the roles of psychosocial therapies in local treatment systems. In particular, their role in creating a cost-effective mix of services...
New research supported by the National Institute on Drug Abuse (NIDA) has found through a comparison of treatment approaches for opioid dependence that, in an emergency setting, combining the medication buprenorphine with on-going care is...
What is already known about this topic?
Fentanyl has a growing presence in the illicit drug market and is involved in an increasing proportion of opioid overdose deaths.
What is added by this report?
Approximately two thirds of...
Alcohol use during pregnancy is the direct cause of fetal alcohol syndrome (FAS). We aimed to estimate the prevalence of alcohol use during pregnancy and FAS in the general population and, by linking these two indicators...
Canadians will soon know whether marijuana will be made legal. If legalised, should the drug carry an age restriction?
This question is central to new research published in the journal Health which suggests that young users report...
Studies have shown that alcohol may play a role in more that 13% of deaths resulting from infectious diseases, including HIV.
Evidence suggests that alcohol consumption negatively affects the fight against HIV primarily by:
New research published in the journal Translational Psychiatry has found that LSD reduces activity in the region of the brain responsible for negative emotions such as fear.
The researchers call this the drug’s ‘de-frightening effect’ and...
Americká pilotní studie publikovaná v časopise Alcoholism: Clinical and Experimental Research zjistila, že nezletilí mladí lidé ve věku od 13 do 20 let s větší pravděpodobností než dospělí hlásí, že vidí marketing alkoholu online. Šetření...
Objective: To analyze successful national smoke-free policy implementation in Colombia, a middle income country.
Materials and methods: Key informants at the national and local levels were interviewed and news sources and government...
This document provides evidence for arguments supporting alcohol marketing regulation, and suggests key elements that can be considered by countries in planning, developing, implementing, and evaluating effective regulation. It also...
Mezi lidmi, kteří se zotavují z poruch užívání návykových látek, ti, kteří kouří, mají větší pravděpodobnost relapsu o tři roky později ve srovnání s těmi, kteří to nedělají, podle nových zjištění publikovaných v časopise Journal of...
Nejnovější díl online kurzu o výzkumu léčby alkoholu. Podívejte se, zda souhlasíte s vlivnými americkými výzkumníky, že "organizační klima je základem celého procesu přijímání inovací", oceníte efekt vysoké fluktuace zaměstnanců a jak ji...
The National Institute on Drug Abuse (NIDA) has published an extended overview detailing the impact of certain drugs on brain functioning, as well as the most common experimental methods used in related research.
Neuroscientists primarily...
Minimální cena 50 pencí za jednotku alkoholu byla schválena poslanci skotského parlamentu v roce 2012. Rozhodnutí čelilo četným právním námitkám ze strany nápojového průmyslu, než skotské soudy v říjnu 2016 rozhodly v jeho prospěch. To...
New research from Cardiff University has found:
