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What Is Xylazine ("Tranq")? Effects, Wounds, Withdrawal, and Getting Help

Written by Benjamin Zohar, NCACIP

Published: 21 June 2026  |  Last Updated: 21 June 2026  |  6 min read

Reviewed by Brandon McNally, RN

Xylazine—known on the...

ABSTRACT

Objective. Tobacco use is a major modifiable risk factor for the four main noncommunicable diseases (NCDs) globally—cardiovascular diseases, chronic respiratory conditions, cancer, and diabetes. Addressing tobacco use through...

A contribution by Jeff Lee from the ISSUP INEP Plus facilitators training course.

A specialist treatment provider for substance use disorder may have the skill to be a comprehensive care provider for substance use disorder but...

Let us...

The 2025 Global Adderall Shortage: Clinical Impact, Public Health Risks, and Implications for Substance Use Professionals

Author: Benjamin Zohar, NCACIP – Nationally Certified Advanced Addiction Intervention Professional, Founder of Interv...

Background
Individuals who experience gambling addiction often face problems in family relationships, job loss, and financial difficulties. Gambling problems worsen when accompanied by substance use.

Case Presentation
A 28-year-old man was...

Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are revolutionizing the management of type 2 diabetes and obesity.  Exciting new research suggests these medications may also hold immense promise for treating...

This section from the UPC 2 Physiology and Pharmacology for Prevention Professionals (p130-133) introduces the main types of psychoactive substances, explains their effects on the brain and body, and clarifies that some commonly used legal...

In 2021, the Commission on Narcotic Drugs (CND) called on UNODC, alongside Member States and partners, to assess the quality of drug prevention, treatment, sustained recovery, and related support services worldwide. This report uses data...

Summary

Background

Repeat offending, also known as criminal recidivism, in people released from prison has remained high over many decades. To address this, psychological treatments have been increasingly used in criminal justice settings...

Addiction and obesity share similar neurological pathways, both linked to compulsive behaviors and the brain's reward system. Research has highlighted the potential of GLP-1 receptor agonists, originally developed for diabetes, to help...

Join the National Institute on Drug Abuse (NIDA) International Program for the 2025 NIDA International Forum, which will be held June 13–14, 2025, at the Sheraton New Orleans Hotel in New Orleans, Louisiana, USA.

The Forum research...

This review outlines challenges that face the alcohol field in closing this treatment gap and offers solutions, including broadening end points for the approval of medications for the treatment of AUD

Fentanyl is a key therapeutic, used in anaesthesia and pain management. It is alsoincreasingly used illicitly and is responsible for a large and growing number of opioidoverdose deaths, especially in North America. A number of factors have...

A significant number of individuals with alcohol use disorder (AUD) do not seek treatment, and the factors influencing treatment-seeking behavior are not well understood. While it is known that alcohol consumption levels can fluctuate with...

Psychedelics have been used across different cultures for thousands of years, with historical evidence of substances like ayahuasca in South America, mescaline from cacti in North and South America, and ibogaine in West Africa. Despite this...

​​​​​​​ISSUP India presents its webinar, "Unravelling Risk-Taking in Youth: Pathways to Positive Change," which focuses on understanding risk-taking behaviours in adolescents and youth.

NDDCB is registered as an education provider in ISSUP International. By design, the Colombo Plan DAP will update the capacity of the NDDCB and other agencies to control drug demand and supply. Majority of NDDCB staff members have completed...