Source: Nelson LF, Yocum VK, Patel KD, Qeadan F, Hsi A, Weitzen S. Cognitive Outcomes of Young Children After Prenatal Exposure to Medications for Opioid Use Disorder: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020;3(3):e201195. doi:10.1001/jamanetworkopen.2020.1195 Key Points Question...

Source: Katzman JG, Takeda MY, Greenberg N, et al. Association of Take-Home Naloxone and Opioid Overdose Reversals Performed by Patients in an Opioid Treatment Program. JAMA Netw Open. 2020;3(2):e200117. doi:10.1001/jamanetworkopen.2020.0117 Key Points Question Is there a benefit associated with...

Source: https://store.samhsa.gov/system/files/pep19-mat-corrections.pdf Medication-assisted treatment (MAT) is the use of FDA-approved medications in combination with behavioral therapies to treat alcohol and opioid use disorders. When provided as part of the rehabilitation and reentry process for...

Source: Scheibe, A., Shelly, S., Gerardy, T. et al. Six-month retention and changes in quality of life and substance use from a low-threshold methadone maintenance therapy programme in Durban, South Africa. Addict Sci Clin Pract 15, 13 (2020). https://doi.org/10.1186/s13722-020-00186-7 Abstract...

Source: Nguyen JL, Gilbert LR, Beasley L, et al. Availability of Naloxone at Rural Georgia Pharmacies, 2019. JAMA Netw Open. 2020;3(2):e1921227. doi:10.1001/jamanetworkopen.2019.21227 Discussion Although the legislative barrier to obtaining naloxone has been addressed in Georgia, naloxone...

Source: Wakeman SE, Larochelle MR, Ameli O, et al. Comparative Effectiveness of Different Treatment Pathways for Opioid Use Disorder. JAMA Netw Open. 2020;3(2):e1920622. doi:10.1001/jamanetworkopen.2019.20622 Key Points Question What is the real-world effectiveness of different treatment pathways...

Source: https://www.thenationalcouncil.org/medication-assisted-treatment-for-opioid-use-disorder-in-jails-and-prisons/?mkt_tok=eyJpIjoiTVRZM09UbGlaVGt3T0RRMiIsInQiOiJOeldcL0wyWGZSbFMxcFhQUkNoY2FkUU9yZkErMDNGelNUY2o4d0NCalJcL1BQTE1QTklDTnAwZlB2VVVrY0wrWVlDTk9na2FzMzhSZnFneXVcL0drblAxdz09In0%3D People...

Source: Huhn AS, Hobelmann JG, Strickland JC, et al. Differences in Availability and Use of Medications for Opioid Use Disorder in Residential Treatment Settings in the United States. JAMA Netw Open. 2020;3(2):e1920843. doi:10.1001/jamanetworkopen.2019.20843 Key Points Question Do residential...

Source: Ahamad, K., Dong, H., Johnson, C. et al. Factors associated with willingness to wear an electronic overdose detection device. Addict Sci Clin Pract 14, 23 (2019). https://doi.org/10.1186/s13722-019-0153-5 Abstract Background North America is in the midst of an opioid overdose epidemic...

Source: Warrington et al. Addict Sci Clin Pract (2020) 15:3 https://doi.org/10.1186/s13722-020-0178-9 Abstract Background Urine drug monitoring for medications for opioid use disorder (MOUD) such as buprenorphine can help to support treatment adherence. The practice of introducing unconsumed...

Source: Pytell, J.D., Buresh, M.E. & Graddy, R. Outcomes of a novel office-based opioid treatment program in an internal medicine resident continuity practice. Addict Sci Clin Pract 14, 46 (2019) doi:10.1186/s13722-019-0175-z Abstract Background The integration of opioid use disorder (OUD) care and...

Source: Darpö, B., Pirner, M., Longstreth, J., & Ferber, G. (2019). Effect of lofexidine on cardiac repolarization during treatment of opioid withdrawal. Drug and alcohol dependence, 205, 107596. Highlights Small mean QTcF increases were observed with lofexidine (<8 ms) on Days 1–2. QTcF mean...

Source: Dietze P, Jauncey M, Salmon A, et al. Effect of Intranasal vs Intramuscular Naloxone on Opioid Overdose: A Randomized Clinical Trial. JAMA Netw Open. 2019;2(11):e1914977. doi: https://doi.org/10.1001/jamanetworkopen.2019.14977 Key Points Question Is 800 μg of naloxone hydrochloride...

Source: CMAJ Open 2019. DOI:10.9778/cmajo.20190026 Abstract Background: Rates of cannabis use among patients receiving methadone maintenance therapy are high, and cannabis use may be associated with outcomes of methadone maintenance therapy. We examined the effect of cannabis use on opioid use in...

Source: Dietze P, Jauncey M, Salmon A, et al. Effect of Intranasal vs Intramuscular Naloxone on Opioid Overdose: A Randomized Clinical Trial. JAMA Netw Open. 2019;2(11):e1914977. doi: https://doi.org/10.1001/jamanetworkopen.2019.14977 Key Points Question Is 800 μg of naloxone hydrochloride...

Source: Hall, O. T., Hall, O. E., McGrath, R. P., & Haile, Z. T. (2019). Years of Life Lost due to Opioid Overdose in Ohio: Temporal and Geographic Patterns of Excess Mortality. Journal of addiction medicine. Abstract Objectives: The aim of the study was to quantify the burden of premature mortality...

Source: Zhong, B. L., Xu, Y. M., Xie, W. X., Lu, J., Yu, W. B., & Yan, J. (2019). Alcohol drinking in Chinese methadone-maintained clients: a self-medication for depression and anxiety?. Journal of addiction medicine, 13(4), 314-321. Abstract Objectives: Unhealthy alcohol use is associated with...

Source: Bedene A, Lijfering WM, Niesters M, et al. Opioid Prescription Patterns and Risk Factors Associated With Opioid Use in the Netherlands. JAMA Netw Open. Published online August 28, 20192(8):e1910223. doi:10.1001/jamanetworkopen.2019.10223 KEY POINTS Question Are the prevalence of opioid...

This guide focuses on using medication-assisted treatment for opioid use disorder in jails and prisons and during the reentry process when justice -involved persons return to the community. It provides an overview of policies and evidence-based practices that reduce the risk of overdose and relapse.

Source: Gicquelais et al. Harm Reduction Journal (2019) 16:46 https://doi.org/10.1186/s12954-019-0317-3 Abstract Background Persons in addiction treatment are likely to experience and/or witness drug overdoses following treatment and thus could benefit from overdose education and naloxone...