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Psychoactive Substances
Psychoactive substances are natural or synthetic substances that act on the central nervous system and alter mental processes such as mood, perception, cognition, consciousness, and behaviour. These substances may be legally prescribed medications (e.g., pain medications or sedatives), legally available substances such as alcohol or caffeine, or controlled or illicit drugs. Psychoactive substances can be used for medical, social, cultural, or recreational purposes, but some carry risks of misuse, dependence, and health or social harms when used in harmful ways.
Online time of Slovak and Czech adults and its relation to Big Five
INTRODUCTION: In the present article, we focused on the relationship between time spent online and factors of Big Five in the population of adults. We assume that there exist the specifics of time spent online in the relation to age, sex...
The shame and stigma among people with comorbid hepatitis C virus and substance use disorder: a narrative review
The presence of dual diagnosis of Hepatitis C Virus (HCV) infection and substance use disorder (SUD) creates a significant medical and psychological burden, frequently intensifying feelings of Stigma and shame in an individual. Individuals...
Alcohol Use, Diabetes, and Mental Health: Risks, Intersections, and Care
The Tobacco Control Scale 2025 in Europe
A European Guide on Dual disorders: Health and Social Responses
This European guide by EUDA highlights the importance of addressing dual disorders, where mental health conditions and substance use disorders occur at the same time. These co-occurring conditions are common and often lead to poorer health...
The Dope Test
Understanding Drug Testing
What Is a Drug Test?
A drug test is the scientific analysis of biological samples to determine whether narcotic drugs, psychoactive substances, or their metabolites are present in the body. Samples may include...
Say "NO" to Drugs
Understanding Psychoactive Substances and Substance Use
What Are Psychoactive Substances?
Psychoactive substances are substances that affect the way the brain and body function, influencing thoughts, emotions, perceptions, and behaviour...
Ice in Khyber Pakhtunkhwa: Understanding Methamphetamine Use and Community Responses
Are There Health Benefits to Going ‘California Sober’?
Some people are going California sober, meaning they are cutting back on or quitting alcohol or other addictive substances in favor of using marijuana. In theory, the lifestyle choice aims to replace more harmful substances with something...
UNODC Current NPS Threats
The UNODC Early Warning Advisory highlights a continued global expansion of new psychoactive substances (NPS), with nearly 1,400 substances reported worldwide. In 2024 alone, a record number of substances were identified, including over 100...
Stimulant Use and Related Harms in Canada: Recent Trends
This report highlights a growing concern around stimulant use and related harms in Canada, particularly involving cocaine and methamphetamine. Data from multiple national sources show that stimulant-related deaths have significantly...
The Pleasure That Doesn't Return: Dopaminergic Synergy, Sexuality and Relapse in Cocaine Addiction
This work emerges from clinical observation in addiction treatment settings regarding a frequent yet systematically overlooked phenomenon: the convergence of cocaine use and sexual activity as a specific relapse mechanism. It is proposed...
El Placer que no Vuelve: Sinergia Dopaminérgica, Sexualidad y Recaída en la Adicción a la Cocaína
Este trabajo surge de la observación clínica en dispositivos de tratamiento de adicciones sobre un fenómeno frecuente y sistemáticamente ignorado: la convergencia entre el consumo de cocaína y la actividad sexual como mecanismo específico...
2026 National Drug Control Strategy - The White House
The 2026 National Drug Control Strategy outlines a comprehensive roadmap to reduce illicit drug use and protect communities across the United States. It prioritizes stopping the flow of drugs and precursor chemicals at all borders through...
La comunidad religiosa y la fe frente al trastorno por uso de sustancias
CCENDU Issue 7 (Part 2): Stimulant Use and Related Harms in Canada — Drivers and Adaptive Responses
This issue is the second of a special two-part series. Part 2 examines key factors driving stimulant use, what these trends mean for different groups of people and the responses being implemented to reduce harms.
Three key points of...
CCENDU Issue 7 (Part 1): Stimulant Use and Related Harms in Canada - Recent Trends
This issue is a special two-part series. The first part features a regional breakdown of reports from seven Canadian Community Epidemiology Network on Drug Use (CCENDU) nodes and five drug checking services from across the country. It...
Everyday discrimination in individuals seeking treatment/receiving support for substance use and caregivers
Background:
Experiencing stigma/discrimination is common in individuals who use substances. However, those with caring responsibilities for individuals who use substances may also be stigmatised and discriminated against (known as...
ROFI CAMEROON takes its “No Addiction Concert” to Banga-Pongo in Douala 3
One of the most innovative and impactful strategies of ROFI Cameroon is the use of music as a tool for social intervention, grassroots sensitization campaigns, conducted directly within local communities.
THE NO ADDICTION CONCERT
The...
Integrated Support for Co-occurring Mental Health and Substance Use Disorders
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