تلاش
Pharmacological Interventions
The use of medication to manage withdrawal symptoms, reduce cravings, or treat co-occurring mental health disorders e.g., methadone, buprenorphine, naltrexone.
Smoking Cessation Support for Regular Smokers in Hungarian Primary Care
Abstract
Objectives: Our study aimed to evaluate the effectiveness of general practitioners’ (GPs’) smoking cessation support (SCS).
Study design: We carried out a cross-sectional study between February and April 2016.
Setting and...
A Meta-Analysis of the Efficacy of Bupropion Sustained-Release for Smoking Cessation in Heavy Smokers
Cigarette smoking damages just about every organ in the body and reduces overall health. Even with the prevalence of accessible nicotine replacement therapies and behavioral counseling, there remains a need for alternative therapies to...
The Role of Adenosine Receptors in Psychostimulant Addiction
Adenosine receptors (AR) are a family of G-protein coupled receptors, comprised of four members, named A1, A2A, A2B, and A3 receptors, found widely distributed in almost all human body tissues and organs. To date, they are known to...
Psychiatric Symptoms in Individuals Who Use Ketamine Versus Methamphetamine
Yanhui Liao
Introduction: Chronic use of both Ketamine (“K powder”) and methamphetamine (MA, “ice”) can induce psychiatric symptoms. This study aimed at exploring drug-induced psychiatric symptoms in chronic ketamine users and MA users.
...الکحل کے استعمال کی خرابی والے مریضوں کے فارماکولوجیکل علاج کے لئے امریکی نفسیاتی ایسوسی ایشن پریکٹس گائیڈ لائن
منطق
اس گائیڈ لائن کا مقصد شراب کے استعمال کی خرابی (اے یو ڈی) کے مریضوں کے لئے دیکھ بھال کے معیار اور علاج کے نتائج کو بہتر بنانا ہے ، جیسا کہ ڈی ایس ایم -5 (امریکی نفسیاتی ایسوسی ایشن 2013) نے وضاحت کی ہے۔ گائیڈ لائن میں خاص طور پر اے یو...
Reviewing Inclusion Health: An Intervention Programme for At-Risk Populations
Inclusion Health is a framework for action that helps find ways of improving the health and well-being for socially excluded groups. These populations, who have in common adverse life experiences and risk factors, such as poverty and...
No Clear Role for Medications in Less Dependent Drinkers
In 2013 nalmefene was authorised for moderating drinking among patients not in need of detoxification, extending pharmacotherapy to less dependent drinkers. Though uniquely authorised for this purpose, this review found other (and probably...
Novel Vaccines against Morphine Heroin
SUMMARY
Drug addiction is one of the most important health problems worldwide. This pathology results in the death of about 500,000 individuals annually around the globe. Despite this scenario, the development of effective drug therapies...
Mouse Party - The Brain on Drugs
This interactive game lets you look into the brain of mice under the influence of different drugs. You can study the different brain mechanisms that are triggered with various common illicit substances.
Transcranial Magnetic Stimulation of Dorsolateral Prefrontal Cortex Reduces Cocaine Use
Abstract
Recent animal studies demonstrate that compulsive cocaine seeking strongly reduces prelimbic frontal cortex activity, while optogenetic stimulation of this brain area significantly inhibits compulsive cocaine seeking, providing a...
Opioid Use and Opioid Use Disorder in Pregnancy
ABSTRACT
Opioid use in pregnancy has escalated dramatically in recent years, paralleling the epidemic observed in the general population. To combat the opioid epidemic, all health care providers need to take an active role. Pregnancy...
The Effectiveness of Illegal Drug Interventions
This Health Research Board document reviews evidence on the effectiveness of interventions in the areas of prevention, harm reduction and long-term recovery from addiction to illegal drugs.
It asks which interventions are effective for:
- ...
An Expanding World of Novel Psychoactive Substances: Opioids
The abuse of novel psychoactive substances (NPS) has been increasing dramatically worldwide since late 2000s. By the end of 2015, more than 560 NPS had been reported to the European Monitoring Centre for Drugs and Drug Addiction. Although...
An Approach to the New Psychoactive Drugs Phenomenon
ABSTRACT
Background: The new psychoactive drugs (NPD) are those that represent a danger to public health and are not prohibited by conventions on international narcotics. The concept also includes new contexts and new routes of consumption...
Cocaine Elicits Autophagic Cytotoxicity via a Nitric Oxide-GAPDH Signaling Cascade
Abstract
Cocaine exerts its behavioral stimulant effects by facilitating synaptic actions of neurotransmitters such as dopamine and serotonin. It is also neurotoxic and broadly cytotoxic, leading to overdose deaths. We demonstrate that the...
A Scientific Development for the Treatment of Cocaine Addiction?
A new study published in the journal Biological Psychiatry claims that one’s desire for cocaine may be reduced by blocking signalling from a specific system in the brain primarily responsible for promoting wakefulness and appetite.
The...
Terminology and Information on Drugs
PREFACE
The UNODC publication Terminology and Information on Drugs introduces basic concepts and materials on substances under international control, which are most frequently manufactured or processed and/or abused, as well as definitions...
The Impact of Alcohol Use and Related Disorders on the HIV Continuum of Care
Alcohol use is highly prevalent globally with numerous negative consequences to human health, including HIV progression, in people living with HIV (PLH). The HIV continuum of care, or treatment cascade, represents a sequence of targets for...
Enzymes Involved in Cocaine Metabolism: A New Pharmacologic Approach to Treat Overdose Due to Cocaine
Abstract English/Spanish
Introduction: New therapeutic strategies against cocaine overdose toxicity have been developed. These new approaches are based on the design and synthesis of proteins involved in the destruction of cocaine before...
Key Points from EMCDDA’s 2016 European Drug Report
As we welcome in the New Year it seems an ideal time to take stock and present the key points from the 2016 European Drug Report (EDR), the European Monitoring Centre for Drug and Addiction’s (EMCDDA) annual review of the European drug...
