Background

Stigma related to drug use is a well-documented barrier to engaging and remaining on medication for opioid use disorder (MOUD), yet little is known about how stigma operates across multiple social and institutional settings in low-resource contexts.

Methods

This qualitative study draws on 40 in-depth interviews with current and former MOUD clients and four focus groups with 35 current clients at an opioid treatment clinic in Dar es Salaam, Tanzania. Transcripts were thematically analyzed to explore how stigma influenced MOUD adherence and retention.

Results

Five themes emerged...

CSUCH’s data visualisation tool can be used to estimate substance use trends across the country. The data helps inform programs, practices, and research to protect communities, save lives, and improve the well-being of people in Canada.

Spotlight: Top 3 causes of death due to substance use in Canada 

More than 200 people died each day due to substance use (SU) in 2020 (the latest year for which data are available). That works out to 73,994 deaths that year. The average age of death due to SU was 45 years. Tobacco use caused 63% (46,366) of SU-related deaths, followed by alcohol at 23%...

Addiction and obesity share similar neurological pathways, both linked to compulsive behaviors and the brain's reward system. Research has highlighted the potential of GLP-1 receptor agonists, originally developed for diabetes, to help manage both appetite and addictive cravings. These medications, such as semaglutide, may regulate addictive behaviors by influencing reward circuits in the brain. However, they come with potential side effects, and their long-term effects are still under investigation.

In addition, a new compound, 5-Methoxy-2-aminoindane (MEAI), is being researched for its...

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