Research

Gender disparities in opioid treatment progress in methadone versus counselling

Citation
Guerrero, E., Amaro, H., Kong, Y. et al. Gender disparities in opioid treatment progress in methadone versus counseling. Subst Abuse Treat Prev Policy 16, 52 (2021). https://doi.org/10.1186/s13011-021-00389-4
Publication Date

The high dropout rate (75%) in opioid use disorder (OUD) treatment among women and racial/ethnic minorities in the United States necessitates a better knowledge of the factors that contribute to treatment success. While therapy and medication for OUD are considered the top standard of care in substance use disorder (SUD) treatment, many people with OUD receive just counseling or methadone-only therapies.

High-dose buprenorphine induction in the emergency department for treatment of opioid use disorder

Citation
Herring AA, Vosooghi AA, Luftig J, et al. High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder. JAMA Netw Open. 2021;4(7):e2117128. doi:10.1001/jamanetworkopen.2021.17128
Publication Date

In response to the rising efficacy of the illicit opioid drug supply and often observed delays in access to follow-up therapy, emergency departments (EDs) occasionally utilize a high-dose buprenorphine induction method for the treatment of opioid use disorder (OUD). The objective of this study is to investigate the safety and tolerability of high-dose (>12 mg) buprenorphine induction for patients with OUD presenting to an ED.

Trends in use of e-cigarette device types and heated tobacco products from 2016 to 2020 in England

Citation
Tattan-Birch, H., Brown, J., Shahab, L. et al. Trends in use of e-cigarette device types and heated tobacco products from 2016 to 2020 in England. Sci Rep 11, 13203 (2021). https://doi.org/10.1038/s41598-021-92617-x
Publication Date

During the past decade, heated aerosolized nicotine delivery systems (HANDS) —mainly e-cigarettes—have surpassed nicotine replacement therapy as the most utilized aids for stopping smoking in England.

Biochemical mechanisms associating alcohol use disorders with cancers

Citation
Rodriguez, F.D.; Coveñas, R. Biochemical Mechanisms Associating Alcohol Use Disorders with Cancers. Cancers 2021, 13, 3548. https://doi.org/10.3390/ cancers13143548
Publication Date
Abstract

The World Health Organization identifies alcohol as a cause of several neoplasias of the oropharynx cavity, esophagus, gastrointestinal tract, larynx, liver, or female breast. We review ethanol’s nonoxidative and oxidative metabolism and one-carbon metabolism that encompasses both redox and transfer reactions that influence crucial cell proliferation machinery.

Variation in brief treatment for substance use disorder: a qualitative investigation of four federally qualified health centres with SBIRT services

Citation
Watson, D.P., Staton, M.D., Dennis, M.L. et al. Variation in brief treatment for substance use disorder: a qualitative investigation of four federally qualified health centers with SBIRT services. Subst Abuse Treat Prev Policy 16, 58 (2021). https://doi.org/10.1186/s13011-021-00381-y
Publication Date

Brief treatment (BT) or regular outpatient alcohol use or substance use disorder (SUD) treatment is a key element of the Screening, Brief Intervention, and Referral to Treatment (SBIRT) model. It can be an effective, short-term, and low-cost treatment option for many people who misuse alcohol and drugs. Nevertheless, inconsistent BT implementation often costs similar to regular outpatient care.

Implementation of tobacco control measures in the Gulf Cooperation Council countries, 2008–2020

Citation
Monshi, S.S., Ibrahim, J. Implementation of tobacco control measures in the Gulf Cooperation Council countries, 2008–2020. Subst Abuse Treat Prev Policy 16, 57 (2021). https://doi.org/10.1186/s13011-021-00393-8
Publication Date

Framework Convention on Tobacco Control (FCTC) was developed by the World Health Organization (WHO) to assist nations in reducing the demand and supply of tobacco. In 2020, 182 nations joined the FCTC, approving to implement the recommended tobacco control measures.

Perspectives of illicit marijuana growers and traders on commercial legalization of marijuana in South Africa: considerations for policy formulation

Citation
Manu, E., Douglas, M., Ntsaba, M.J. et al. Perspectives of illicit marijuana growers and traders on commercial legalisation of marijuana in South Africa: considerations for policy formulation. Subst Abuse Treat Prev Policy 16, 54 (2021). https://doi.org/10.1186/s13011-021-00391-w
Publication Date

Over the past era, there has been a call for legalizing marijuana cultivation and trading for commercial purposes in South Africa. Advocates of the call argue that the criminalization of commercial marijuana cultivation and trading has failed to stop illicit marijuana cultivation and trading. Nevertheless, the views of those who economically benefit from the illicit marijuana trade on its legalization remain empirically unsolicited.

High-dose buprenorphine induction in the emergency department for treatment of opioid use disorder

Citation
Herring AA, Vosooghi AA, Luftig J, et al. High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder. JAMA Netw Open. 2021;4(7):e2117128. doi:10.1001/jamanetworkopen.2021.17128
Publication Date

Abstract

Importance: Emergency departments (EDs) sporadically use a high-dose buprenorphine induction strategy for the treatment of opioid use disorder (OUD) in response to the increasing potency of the illicit opioid drug supply and commonly encountered delays in access to follow-up care.

Global burden of cancer in 2020 attributable to alcohol consumption

Citation
Rumgay, H., Shield, K., Charvat, H., Ferrari, P., Sornpaisarn, B., Obot, I., ... & Soerjomataram, I. (2021). Global Burden of Cancer in 2020 Attributable to Alcohol Consumption: A Population-Based Study.

​​​​​​Each year there are 3 million deaths as a result of the harmful use of alcohol.

As alcohol gets broken down, chemicals affect the way our body sends signals and communicates and increase the chances of developing cancer.

In this article, published in Lancet Oncology, the researchers present global, regional, and national estimates of alcohol-attributable cancer burden in 2020.

Findings:

Short-Term Secondary Effects of a School-Based Drug Prevention Program: Cluster-Randomized Controlled Trial of the Brazilian Version of DARE’s Keepin’ it REAL

Citation
Valente, J.Y., Sanchez, Z.M. Short-Term Secondary Effects of a School-Based Drug Prevention Program: Cluster-Randomized Controlled Trial of the Brazilian Version of DARE’s Keepin’ it REAL. Prev Sci (2021). https://doi.org/10.1007/s11121-021-01277-w
Publication Date

Abstract

This study aimed to evaluate the effectiveness of the drug and violence resistance educational program (PROERD) on short-term secondary outcomes, such as intentions to use drugs, attitudes toward drugs, school experience, and life skills (refusal, decision-making, and communication).

The relationship between early childhood trauma and the rewarding effects of morphine

Citation
Carlyle, M., Broomby, R., Simpson, G., Hannon, R., Fawaz, L., Mollaahmetoglu, O. M., ... & Morgan, C. J. (2021). A randomised, double‐blind study investigating the relationship between early childhood trauma and the rewarding effects of morphine. Addiction Biology, e13047.

Research from the University of Exeter has highlighted how childhood trauma can make individuals more sensitive to the pleasurable and motivational effects of opioids and less sensitive to the negative consequence of the drugs.

The research, which has been published in the journal of Addiction Biology, aimed to assess the impact of childhood trauma on responses to morphine and pain processing.

Substance Use Among Young Mothers: An Analysis of Facebook Posts

Citation
Oram D, Tzilos Wernette G, Nichols L, Vydiswaran V, Zhao X, Chang T. Substance Use Among Young Mothers: An Analysis of Facebook Posts. JMIR Pediatr Parent 2018;1(2):e10261 URL: https://pediatrics.jmir.org/2018/2/e10261 DOI: 10.2196/10261
Publication Date
Abstract

Background:Substance use among young pregnant women is a common and significant public health concern associated with a number of adverse outcomes for both mothers and infants. Social media posts by young women can provide valuable, real-world insight into their perceptions of substance use immediately before and during pregnancy.

 

Reporting treatment fidelity in behavioral tobacco treatment clinical trials: scoping review and measurement recommendations

Citation
Ramzi G Salloum, Alana M Rojewski, Megan E Piper, Janice A Blalock, Belinda Borrelli, Lindsay M Boyce, Jennifer A Minnix, Omara Dogar, Rachel L Tomko, Douglas E Jorenby, Chris Kotsen, Jamie S Ostroff, Treatment Fidelity Workgroup of the SRNT Treatment Network, Reporting Treatment Fidelity in Behavioral Tobacco Treatment Clinical Trials: Scoping Review and Measurement Recommendations, Nicotine & Tobacco Research, 2021;, ntab140, https://doi.org/10.1093/ntr/ntab140
Publication Date

Abstract

Introduction:

Is telemedicine the answer to rural expansion of medication treatment for opioid use disorder? Early experiences in the feasibility study phase of a National Drug Abuse Treatment Clinical Trials Network Trial

Citation
Hser, YI., Ober, A.J., Dopp, A.R. et al. Is telemedicine the answer to rural expansion of medication treatment for opioid use disorder? Early experiences in the feasibility study phase of a National Drug Abuse Treatment Clinical Trials Network Trial. Addict Sci Clin Pract 16, 24 (2021). https://doi.org/10.1186/s13722-021-00233-x
Publication Date
Abstract

Telemedicine (TM) enabled by digital health technologies to provide medical services has been considered a key solution to increasing health care access in rural communities.

Plausibility of patient-centred care in high-intensity methadone treatment: Reflections of providers and patients

Citation
Marshall, K., Maina, G. & Sherstobitoff, J. Plausibility of patient-centred care in high-intensity methadone treatment: reflections of providers and patients. Addict Sci Clin Pract 16, 42 (2021). https://doi.org/10.1186/s13722-021-00251-9
Publication Date

Abstract

Background: Patients with opioid use disorder (OUD) often have complex health care needs. Methadone is one of the medications for opioid use disorder (MOUD) used in the management of OUDs. Highly restrictive methadone treatment—which requires patient compliance with many rules of care—often results in low retention, especially if there is inadequate support from healthcare providers (HCPs).

Uso de drogas para adolescentes antes e durante as políticas nacionais de distanciamento social COVID-19

Citation
Miech, R., Patrick, M. E., Keyes, K., O’Malley, P. M., & Johnston, L. (2021). Adolescent Drug Use Before and During US National COVID-19 Social Distancing Policies. Drug and Alcohol Dependence, 108822.

Durante a pandemia COVID-19, países ao redor do mundo introduziram restrições de bloqueio e medidas de distanciamento social para reduzir a propagação do vírus. Os pesquisadores estão interessados em entender como essas políticas e novas medidas influenciaram os comportamentos de consumo em determinados grupos.

Development of an unannounced standardized patient protocol to evaluate opioid use disorder treatment in pregnancy for American Indian and rural communities

Citation
Kelley, A.T., Smid, M.C., Baylis, J.D. et al. Development of an unannounced standardized patient protocol to evaluate opioid use disorder treatment in pregnancy for American Indian and rural communities. Addict Sci Clin Pract 16, 40 (2021). https://doi.org/10.1186/s13722-021-00246-6
Publication Date

Abstract

Background: Opioid use disorder (OUD) disproportionately impacts rural and American Indian communities and has quadrupled among pregnant individuals nationwide in the past two decades. Yet, limited data are available about access and quality of care available to pregnant individuals in rural areas, particularly among American Indians (AIs).

Reimaginando breves intervenções para o álcool: Rumo a um paradigma adequado para o século XXI?

Citation
McCambridge, J. Reimagining brief interventions for alcohol: towards a paradigm fit for the twenty first century?. Addict Sci Clin Pract 16, 41 (2021). https://doi.org/10.1186/s13722-021-00250-w
Publication Date

abstrair

Histórico: Não há mais apoio à ideia de que apenas programas de intervenção breves podem contribuir significativamente para a melhoria da saúde da população relacionada ao álcool. Como resultado, crescem os apelos por grandes inovações e mudanças de paradigma, notadamente entre os líderes da pesquisa.

Adaptação cultural de instrumentos de medição sobre estigma e doença mental na Cidade do México

Citation
Mora-Ríos, J., Bautista-Aguilar, N., Natera, G., & Pedersen, D. (2013). Adaptación cultural de instrumentos de medida sobre estigma y enfermedad mental en la Ciudad de México. Salud Mental, 36(1), 9-18. doi:https://doi.org/10.17711/SM.0185-3325.2013.002

resumo

Este trabalho faz parte de um estudo colaborativo envolvendo equipes de pesquisa no Canadá e no México. O objetivo geral é descrever o processo de adaptação cultural e validação semântica de três instrumentos de medição sobre estigma e doença mental na Cidade do México.

Tabagismo e fatores associados entre pessoas vivendo com HIV em Uganda

Citation
Noreen Dadirai Mdege, PhD, Fredrick Edward Makumbi, PhD, Ronald Ssenyonga, MSc, Frances Thirlway, PhD, Joseph K B Matovu, PhD, Elena Ratschen, PhD, Kamran Siddiqi, PhD, Kellen Nyamurungi Namusisi, MSc, Tobacco Smoking and Associated Factors Among People Living With HIV in Uganda, Nicotine & Tobacco Research, Volume 23, Issue 7, July 2021, Pages 1208–1216, https://doi.org/10.1093/ntr/ntaa262

As taxas de tabagismo entre as pessoas vivendo com HIV são maiores do que o número de pessoas que fumam dentro da população em geral.

Este artigo, publicado no Journal of Nicotine and Tobacco, examina os padrões e comportamentos de tabagismo de pessoas vivendo com HIV e que estão recebendo cuidados em Uganda.

Prevalência e fatores relacionados ao consumo de álcool em adolescentes gestantes: revisão sistemática

Citation
Quintana-Lagunas, R., Armendáriz-García, N. A., & Silva, L. I. M. (2021). Prevalencia y factores relacionados con el consumo de alcohol en adolescentes embarazadas: una revisión sistemática. Revista inteRnacional de investigación en adicciones, 7(1), 43-51.

resumo

Introdução: recomenda-se o consumo de álcool durante a gravidez (CADE) que produz problemas físicos, cognitivos e comportamentais na mãe e no feto, por isso recomenda-se a abstinência dessa substância durante a gravidez; no entanto, fatores presentes em adolescentes podem estar relacionados ao aparecimento ou continuação do consumo de álcool durante a gravidez.

Primata Ventral Striatum mantém representações neurais do valor de objetos previamente recompensados para busca habitual

Citation
Kang, J., Kim, H., Hwang, S.H. et al. Primate ventral striatum maintains neural representations of the value of previously rewarded objects for habitual seeking. Nat Commun 12, 2100 (2021). https://doi.org/10.1038/s41467-021-22335-5
Publication Date

abstrair

O estriado ventral (VS) é considerado uma região-chave que atualiza de forma flexível as recentes mudanças nos valores de recompensa para o aprendizado do hábito. No entanto, esse processo de atualização pode não servir para manter comportamentos habituais aprendidos, que são insensíveis às mudanças de valor.

Atención visual a las señales de consumo de tabaco: Un estudio preliminar empleando el seguimiento ocular

Citation
Rojas, M. A. T., Carranza, N. J. V., Iturria, F. A. R., & Castillo, R. J. (2021). Atención visual a las señales de consumo de tabaco: un estudio preliminar empleando el seguimiento ocular. Revista inteRnacional de investigación en adicciones, 7(1), 16-24.

Retomou

Introdução: la atención es un proceso básico relacionado con el comportamiento adictivo. En fumadores, los estímulos asociados al consumo filho relevantes debido a que están presentes en el inicio y en la consolidación del hábito tabáquico.

Menor matéria cinzenta regional em transtornos do uso de álcool: evidência de uma meta-análise baseada em voxel

Citation
Li, L., Yu, H., Liu, Y. et al. Lower regional grey matter in alcohol use disorders: evidence from a voxel-based meta-analysis. BMC Psychiatry 21, 247 (2021). https://doi.org/10.1186/s12888-021-03244-9
Publication Date

fundo:

Pesquisas anteriores utilizando técnicas de neuroimagem do cérebro inteiro revelaram diferenças estruturais da matéria cinzenta (GM) em pacientes com transtorno do uso de álcool (AUD). No entanto, alguns dos achados divergem de outros estudos de neuroimagem e requerem mais replicação.

Tratamento de cuidados crônicos para cessação do tabagismo em pacientes com doença mental grave: um ensaio randomizado piloto

Citation
Busch, A.M., Nederhoff, D.M., Dunsiger, S.I. et al. Chronic care treatment for smoking cessation in patients with serious mental illness: a pilot randomized trial. BMC Psychiatry 21, 104 (2021). https://doi.org/10.1186/s12888-021-03113-5
Publication Date

fundo:

As taxas de tabagismo entre aqueles com doença mental grave (IDS) são duas a três vezes maiores do que para a população em geral. O tabagismo raramente é abordado em ambientes de saúde mental. São necessárias estratégias inovadoras de divulgação e tratamento para enfrentar essas disparidades.

Current Status of Violence, Suicide, Alcohol Use, and Stigma in Mexico

Citation
Borges, G. (2021). Current status of violence, suicide, alcohol use, and stigma in Mexico. Salud Mental, 44(2), 41-42. doi:https://doi.org/10.17711/SM.0185-3325.2021.007

Abstract

Studies on the Global Burden of Disease (GBD) and its risk factors have shown worldwide the preponderant role of accidents and violence in the burden of disease and the role of alcohol consumption as a main risk factor in the current epidemiological profile (GBD 2019 Risk Factors Collaborators, 2020; GBD 2019 Diseases and Injuries Collaborators, 2020).

Apoiar as mulheres a acessar o tratamento adequado

Citation
Ivers, Jo-Hanna and Giulini, Francesca and Paul, Gillian (2021) Supporting women to access appropriate treatment study. Dublin: Trinity College Dublin.

Support Women to Access Appropriate Treatment (SWAAT) é uma Iniciativa Estratégica de Saúde da Estratégia Nacional de Drogas Strand 2 que visa construir capacidade comunitária para apoiar as mulheres a acessar o tratamento e a recuperação do uso de drogas e álcool nas áreas de Tallaght e Ballyfermot LDATF.

Violência de parceiros íntimos e sua relação com o consumo de substâncias por homens e mulheres mexicanos: Pesquisa Nacional sobre Vícios

Citation
Natera Rey, G., Moreno López, M., Toledano-Toledano, F., Juárez García, F., & Villatoro Velázquez, J. (2021). Intimate-partner violence and its relationship with substance consumption by Mexican men and women: National Survey on Addictions. Salud Mental, 44(3), 135-143. doi:https://doi.org/10.17711/SM.0185-3325.2021.018

abstrair

Introdução: Os achados da pesquisa sobre violência de parceiros íntimos (IPV) têm focado principalmente em mulheres como vítimas de violência. Estudos recentes mostram a importância da violência infligida pelas mulheres em relação aos homens ou entre casais do mesmo sexo.

Caracterização do consumo de álcool e problemas relacionados em estudantes universitários da Cidade do México

Citation
Cordero-Oropeza, R., García-Méndez, M., Cordero-Oropeza, M., & Corona-Maldonado, J. (2021). Characterization of alcohol consumption and related problems in university students from Mexico City. Salud Mental, 44(3), 107-115. doi:https://doi.org/10.17711/SM.0185-3325.2021.015

abstrair

Introdução: No México, o consumo de álcool é o principal problema relacionado ao uso de substâncias entre estudantes universitários.

Objetivo: Analisar padrões emergentes de consumo de álcool em estudantes de uma universidade pública através da administração de uma pesquisa online.

Associação de responsabilidade genética ao início do tabagismo com uso de cigarro eletrônico em adultos jovens: Estudo de coorte

Citation
Khouja JN, Wootton RE, Taylor AE, Davey Smith G, Munafò MR (2021) Association of genetic liability to smoking initiation with e-cigarette use in young adults: A cohort study. PLoS Med 18(3): e1003555.
Publication Date

fundo:

O tabagismo e o uso de cigarros eletrônicos estão fortemente associados, mas atualmente não está claro se essa associação é causal ou devido a fatores compartilhados que influenciam ambos os comportamentos, como uma responsabilidade genética compartilhada. O objetivo deste estudo foi investigar se os escores de risco poligênico (S PR) para a iniciação do tabagismo estão associados ao uso de cigarros eletrônicos.