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Medication Assisted Treatment (MAT)

Network to discuss various topics in MAT application and policy.

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Brian Morales
U.S. Department of State
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Jose Luis Vazquez Martinez

Brenipatida para los trastornos por uso de sustancias: resumen de la evidencia actual (Septiembre 2026)

Jose Luis Vazquez Martinez - 6 Septiembre 2026

Fuente:https://sin-adiccion.blogspot.com/2026/09/brenipatide-brenipatida.html

Dado el estado actual de la evidencia, la brenipatida no debe sustituir a los tratamientos aprobados o recomendados por las guías clínicas para los trastornos por consumo de alcohol, opioides o tabaco fuera del contexto de un ensayo clínico.

 

References / Referencias

  • Cai, M., Choi, T., Xie, Y., & Al-Aly, Z. (2026). Glucagon-like peptide-1 receptor agonists and risk of substance use disorders among US veterans with type 2 diabetes: Cohort study. BMJ, 392, e086886. https://doi.org/10.1136/bmj-2025-086886 [pubmed...
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Jose Luis Vazquez Martinez

Emergency Departments Need to Train and Hire More Sub-Specialists in Addiction Medicine

Jose Luis Vazquez Martinez - 2 September 2026
Source: Spadaro, A., Kelly, T., Morris, J., & Heeney, M. E. (2026). Emergency Departments Need to Train and Hire More Sub-Specialists in Addiction Medicine. AEM Education and Training, 10(3), e70184. https://doi.org/10.1002/aet2.70184 According to the 2024 National Survey on Drug Use and Health, 48...
Emergency Departments Need to Train and Hire More Sub‐Specialists in Addiction Medicine.pdf
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Jose Luis Vazquez Martinez

Whole body physiology model to simulate respiratory depression of fentanyl and associated naloxone reversal

Jose Luis Vazquez Martinez - 2 September 2026
Source: Baird, A., White, S. A., Das, R., Tatum, N., & Bisgaard, E. K. (2024). Whole body physiology model to simulate respiratory depression of fentanyl and associated naloxone reversal. Communications Medicine, 4, 114. https://doi.org/10.1038/s43856-024-00536-5 Abstract Background Opioid use in...
Whole body physiology model to simulate respiratory depression of fentanyl and associated naloxone reversal.pdf
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Jose Luis Vazquez Martinez

Estimating naloxone need in the USA across fentanyl, heroin, and prescription opioid epidemics: a modelling study

Jose Luis Vazquez Martinez - 2 September 2026
Source: Irvine, M. A., Oller, D., Boggis, J., Bishop, B., Coombs, D., Wheeler, E., Doe-Simkins, M., Walley, A. Y., Marshall, B. D. L., Bratberg, J., & Green, T. C. (2022). Estimating naloxone need in the USA across fentanyl, heroin, and prescription opioid epidemics: A modelling study. The Lancet...
Estimating naloxone need in the USA across fentanyl, heroin, and prescription opioid epidemics a modelling study.pdf
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Jose Luis Vazquez Martinez

Naloxone Dosing After Opioid Overdose in the Era of Illicitly Manufactured Fentanyl

Jose Luis Vazquez Martinez - 2 September 2026
Source: Carpenter, J., Murray, B. P., Atti, S., Moran, T. P., Yancey, A., & Morgan, B. (2020). Naloxone dosing after opioid overdose in the era of illicitly manufactured fentanyl. Journal of Medical Toxicology, 16(1), 41-48. https://doi.org/10.1007/s13181-019-00735-w Abstract Introduction Illicitly...
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Hala Najm

Substance Use and Health Competencies for All Prescribers

Shared by Hala Najm - 28 August 2026
Format
Guide
Published by / Citation
The Canadian Centre on Substance Use and Addiction (CCSA)

Developed by the Canadian Centre on Substance Use and Addiction (CCSA), the Workforce Competencies provide an evidence-informed framework outlining the knowledge, skills, values and behaviours needed by professionals working in substance use health. The resource includes technical and behavioural competencies across different proficiency levels, alongside practical tools to support recruitment, performance management, professional development and competency-based workforce planning.

It is a useful resource for practitioners, managers, educators and organisations looking to strengthen...

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Jose Luis Vazquez Martinez

Methadone vs Buprenorphine-Naloxone in Opioid Overdose Survivors

Jose Luis Vazquez Martinez - 27 August 2026
Source: Kleinman RA, Larney S, Sule NO, Ma C, Hauck TS, Kurdyak P. Methadone vs Buprenorphine-Naloxone in Opioid Overdose Survivors. JAMA Netw Open. 2026;9(8):e2629313. doi:10.1001/jamanetworkopen.2026.29313 Key Points Question Among individuals with a past-year opioid overdose starting opioid...
Methadone vs Buprenorphine-Naloxone in Opioid Overdose Survivors.pdf
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Jose Luis Vazquez Martinez

Evaluating the optimal duration of medication treatment for opioid use disorder

Jose Luis Vazquez Martinez - 20 May 2026
Source: Hayes, C. J., Raciborski, R. A., Acharya, M., Noor, N. B., Nunes, E. V., & Winhusen, T. J. (2026). Evaluating the optimal duration of medication treatment for opioid use disorder. Addiction, 121(4), 922-933. https://doi.org/10.1111/add.70211 Abstract Background and aims Clinicians have...
Addiction - 2026 - Hayes - Evaluating the optimal duration of medication treatment for opioid use disorder_1.pdf
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Jose Luis Vazquez Martinez

Cost-Effectiveness of the START Hospital Addiction Consultation Service for Opioid Use Disorder Treatment

Jose Luis Vazquez Martinez - 7 May 2026
Source: Okunogbe A, Peltz A, Danovitch I, Ober AJ, Nuckols TK. Cost-Effectiveness of the START Hospital Addiction Consultation Service for Opioid Use Disorder Treatment. JAMA Netw Open. 2026;9(5):e2611324. doi:10.1001/jamanetworkopen.2026.11324 Key Points Question Is a hospital-based addiction...
Cost-Effectiveness of the START Hospital Addiction Consultation Service for Opioid Use Disorder Treatment_0.pdf
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Jose Luis Vazquez Martinez

Driving Distance From US Jails to Opioid Treatment Programs

Jose Luis Vazquez Martinez - 2 April 2026
Source: Saloner, B., O’Rourke, A., Ruelas-Vargas, K., Song, M., Ramsey, K. S., & Bandara, S. (2026). Driving Distance From US Jails to Opioid Treatment Programs. JAMA Network Open, 9(3), e264044-e264044. Discussion In this study, 51.5% of US jails were located more than a 30-minute drive from an OTP...
Driving Distance From US Jails to Opioid Treatment Programs_0.pdf
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Jose Luis Vazquez Martinez

Buprenorphine initiation from fentanyl using low-dose intramuscular ketamine: a pilot study

Jose Luis Vazquez Martinez - 12 February 2026
Source: Engeriser, J.L., Hutch, T., Smith, C.L. et al. Buprenorphine initiation from fentanyl using low-dose intramuscular ketamine: a pilot study. Addict Sci Clin Pract 21, 23 (2026). https://doi.org/10.1186/s13722-026-00649-3 Abstract Background Buprenorphine is an effective medication for...
Buprenorphine initiation from fentanyl using low-dose intramuscular ketamine a pilot study.pdf
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Jose Luis Vazquez Martinez

Opioid Treatment Programs’ Medicaid Patient Retention Rates

Jose Luis Vazquez Martinez - 10 February 2026
Source: DeLisle, D. E., Mark, T. L., Katz, C., Dowd, W. N., Barch, D., & Kluckman, M. (2026). Opioid Treatment Programs’ Medicaid Patient Retention Rates. JAMA Network Open, 9(1), e2553538. Key Points Question What are the Medicaid patient retention rates in opioid treatment programs (OTPs) in the...
Opioid Treatment Programs’ Medicaid Patient Retention Rates.pdf
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Jose Luis Vazquez Martinez

Travel Time to Methadone Treatment Via Personal Vehicle vs Public Transit

Jose Luis Vazquez Martinez - 5 February 2026
Source: Howell BA, Kim J, Thornhill TA, et al. Travel Time to Methadone Treatment Via Personal Vehicle vs Public Transit. JAMA Netw Open. 2026;9(2):e2557361. doi:10.1001/jamanetworkopen.2025.57361 Key Points Question How does transportation access to methadone treatment for opioid use disorder via...
Travel Time to Methadone Treatment Via Personal Vehicle vs Public Transit.pdf
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Goodman Sibeko

Webinar Reflection: Integrated Care for Syndemics, Bringing SUD, HIV & HCV Treatment Together

Shared by Goodman Sibeko - 12 December 2025
Photograph of Dr Sarah Kattakuzhy
ISSUP hosted a webinar on 4 December 2025 with Dr Sarah Kattakuzhy, exploring integrated care for the syndemic of SUD, HIV, and HCV. She highlighted that these conditions often occur together and intensify one another, making siloed approaches ineffective. The session showcased strong evidence that integrated care models; whether co-located, mobile, telemedicine-supported, or provider-integrated; improve treatment uptake, viral suppression, and HCV cure rates. Case studies illustrated how person-centred, joined-up care strengthens trust, stability, and quality of life. The discussion emphasized the significant opportunity to scale integrated, flexible, and humane care models across diverse health systems.
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Jose Luis Vazquez Martinez

Overdose education and naloxone distribution in jails: Examining the impact of the Communities That HEAL intervention in 4 states

Jose Luis Vazquez Martinez - 13 September 2025
Source: Hunt, T., Oser, C., Friedmann, P. et al. Overdose education and naloxone distribution in jails: Examining the impact of the Communities That HEAL intervention in 4 states. Health Justice 13, 47 (2025). https://doi.org/10.1186/s40352-025-00353-5 Abstract Background Opioid-related overdose is...
Overdose education and naloxone distribution in jails Examining the impact of the Communities That HEAL intervention in 4 states.pdf
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Goodman Sibeko

Webinar reflection: Exploring Multiple Pathways of Recovery

Shared by Goodman Sibeko - 27 June 2025
Title slide for PowerPoint presentation titled Exploring Pathways of Recovery by Dr Haner Hernández.
Format
Community update

ISSUP, in collaboration with Faces & Voices of Recovery, has launched a new Global Recovery Network webinar series to spotlight diverse perspectives on recovery. The first webinar featured Dr. Haner Hernández, a respected expert in the field and a person in long-term recovery. Dr. Hernández currently serves as a Senior Consultant to the Massachusetts Department of Public Health and plays a key role in advancing health equity, workforce development, and recovery support. His presentation provided an insightful and inclusive overview of multiple pathways to recovery, grounded in both...

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Goodman Sibeko

Consulta de la Unión Africana para la Reducción de la Demanda de Drogas de 2025 en Arusha, Tanzania

Shared by Goodman Sibeko - 13 Diciembre 2024
Asistentes a la Consulta de la Unión Africana para la Reducción de la Demanda de Drogas en Arusha, Tanzania

La Comisión de la Unión Africana (AUC) ha celebrado una consulta continental anual para la Reducción de la Demanda de Drogas (DDR) desde 2015.  Cada uno de los Estados miembros de la AUC está representado por sus respectivos puntos focales nacionales de desarme, desmovilización y reintegración, lo que brinda a los Estados miembros la oportunidad de presentar las actividades nacionales de desarme, desmovilización y reintegración en una plataforma de revisión por pares que también permite la participación de expertos en la materia invitados.  La consulta de este año se llevó a cabo en Arusha,...

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Jose Luis Vazquez Martinez

Methadone Induction in Primary Care for Opioid Dependence: A Pragmatic Randomized Trial (ANRS Methaville)

Jose Luis Vazquez Martinez - 22 March 2024
Source: Carrieri PM, Michel L, Lions C, Cohen J, Vray M, Mora M, et al. (2014) Methadone Induction in Primary Care for Opioid Dependence: A Pragmatic Randomized Trial (ANRS Methaville). PLoS ONE 9(11): e112328. https://doi.org/10.1371/journal.pone.0112328 Abstract Objective Methadone coverage is...
Methadone Induction in Primary Care for Opioid Dependence A Pragmatic Randomized Trial ANRS Methaville.pdf
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Jose Luis Vazquez Martinez

Scaling up overdose education and naloxone distribution in Kentucky: adoption and reach achieved through a “hub with many spokes” model

Jose Luis Vazquez Martinez - 1 December 2023
Source: Knudsen, H.K., Freeman, P.R., Oyler, D.R. et al. Scaling up overdose education and naloxone distribution in Kentucky: adoption and reach achieved through a “hub with many spokes” model. Addict Sci Clin Pract 18, 72 (2023). https://doi.org/10.1186/s13722-023-00426-6 Abstract Background...
Scaling up overdose education and naloxone distribution in Kentucky adoption and reach achieved through a hub with many spokes model.pdf
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James Harvey

Apply for In-Person Training at the Thessaloniki 2024 Global Event

Shared by James Harvey (ISSUP staff) - 28 November 2023
The 2024 Global Event will be held in Thessaloniki, Greece between 24th & 28th June, 2024. The event is organised by ISSUP and ISSUP Greece, INL, the Centers for the Prevention of Addictions, the Promotion of Psychosocial Health SEIRIOS and ICUDDR.  The event will take place in the historic center of Thessaloniki, on the premises of the ‘International Exhibition & Congress Centre of TIF-HELEXPO’ and surrounding conference rooms in museums and social institutions.
We are excited to announce that registration for the in-person training sessions at the Thessaloniki 2024 Global Event is now live!
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