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How States Are Tackling the Opioid Crisis
Avoidable Emergency Department Visits: A Starting Point
Abstract
Objective
To better characterize and understand the nature of a very conservative definition of ‘avoidable’ emergency department (ED) visits in the United States to provide policy-makers insight into what interventions can target...
Overdose Deaths Related to Fentanyl and Its Analogs
Summary
What is already known about this topic?
Illicitly manufactured fentanyl has become a significant contributor to unintentional overdose deaths in the United States.
What is added by this report?
Approximately 90% of unintentional...
Trends in Deaths Involving Heroin and Synthetic Opioids Excluding Methadone, and Law Enforcement Drug Product Reports
Summary
What is already known about this topic?
Opioid overdose deaths in the United States have been increasing since 1999, initially driven by prescription opioid misuse and more recently by heroin and other illicit opioid use.
What is...
Smartphone Ownership among US Adult Cigarette Smokers
ABSTRACT
Background: Despite increasing interest in smartphone apps as a platform for delivery of tobacco cessation interventions, no previous studies have evaluated the prevalence and characteristics of smokers who can access smartphone...
Opioid Use and Opioid Use Disorder in Pregnancy
ABSTRACT
Opioid use in pregnancy has escalated dramatically in recent years, paralleling the epidemic observed in the general population. To combat the opioid epidemic, all health care providers need to take an active role. Pregnancy...
Teachers and Coaches in Adolescent Social Networks Are Associated with Healthier Self-Concept and Decreased Substance Use
ABSTRACT
BACKGROUND
Poor academic (eg. “I am a bad student”) and behavioral (eg. “I am a troublemaker”) self-concepts are strongly linked to adolescent substance use. Social networks likely influence self-concept. However, little is...
Substance Use among Transgender Students in California Public Middle and High Schools
ABSTRACT
BACKGROUND
Transgender adolescents face tremendous social stress in families and schools, which often leads to behavioral health disparities. This study assessed whether rates of substance use were higher among transgender...
Effect of Marijuana Use on Cardiovascular and Cerebrovascular Mortality
Abstract
Background
Reports associate marijuana use with cardiovascular emergencies. Studies relating marijuana use to cardiovascular mortality are scarce. Recent advance towards marijuana use legalization emphasizes the importance of...
Alcohol Screening and Brief Intervention: A Potential Role in Cancer Prevention for Young Adults
Excessive or risky alcohol use is a preventable cause of significant morbidity and mortality in the U.S. and worldwide. Alcohol use is a common preventable cancer risk factor among young adults; it is associated with increased risk of...
The Effects of Cannabis among Adults with Chronic Pain and an Overview of General Harms
Abstract
Background: Cannabis is increasingly available for the treatment of chronic pain, yet its efficacy remains uncertain.
Purpose: To review the benefits of plant-based cannabis preparations for treating chronic pain in adults and...
Heavy Drinking and the Adolescent Brain
During adolescence, the brain is still maturing. This includes not only biological, but also psychosocial behavioural development.
So, what are the effects of heavy drinking on the adolescent brain?
This question is the focus of a...
The Brain’s Role in Drug Addiction
Latest research suggests that the impairment of the lateral habenula (LB) – the region of the brain known to register negative experiences – can contribute to the development of drug addiction.
The study, conducted on laboratory rats by...
How to Tackle America’s Opioid Crisis?
Much the result of a poor understanding of how to treat chronic pain, the United States has in recent years been rocked by an unprecedented drug crisis: The opioid epidemic.
Opioids include drugs derived from opium, such as heroin, as...
Morphine versus Methadone Treatment for Neonatal Withdrawal and Impact on Early Infant Development
Abstract
Objective: Compare developmental outcomes in infants treated with morphine versus methadone.
Method: Retrospective chart review of newborns identified through use of ICD-9 code for neonatal abstinence syndrome (NAS). Thirty-six...
The Role of Science in Addressing the Opioid Crisis
Opioid misuse and addiction is an ongoing and rapidly evolving public health crisis, requiring innovative scientific solutions. In response, and because no existing medication is ideal for every patient, the National Institutes of Health...
Hippocampus-Dependent Memory and Allele-Specific Gene Expression in Adult Offspring of Alcohol-Consuming Dams after Neonatal Treatment with Thyroxin or Metformin
Fetal alcohol spectrum disorder (FASD), the result of fetal alcohol exposure (FAE), affects 2–11% of children worldwide, with no effective treatments. Hippocampus-based learning and memory deficits are key symptoms of FASD. Our previous...
Alcohol Affects Brain Functional Connectivity and Its Coupling with Behavior: Greater Effects in Male Heavy Drinkers
Abstract
Acute and chronic alcohol exposure significantly affect behavior but the underlying neurobiological mechanisms are still poorly understood. Here, we used functional connectivity density (FCD) mapping to study alcohol-related...
Study Finds Increased Cannabis Use among Certain US States
Over the last few decades, the United States has entered a new phase in its cannabis control policies.
As of November 2016, 28 US states and Washington, D.C. had legalised cannabis use for medicinal purposes.
Eight of these and Washington...
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