Quick take: Yes—some patients do benefit from Suboxone® (buprenorphine/naloxone) for kratom / 7-hydroxymitragynine (7-OH) withdrawal and stabilization, based mainly on case reports and clinician experience—not randomized trials. Decisions should be individualized with a qualified prescriber in New York.

7-Hydroxymitragynine (7-OH) Detox in New York: What to Know About Kratom’s Active Alkaloid

Benjamin Zohar, NCACIP  •  November 8, 2025  •  Last reviewed: November 8, 2025

Quick take: 7-Hydroxymitragynine (7-OH) is a primary active alkaloid in kratom products. Heavy or prolonged use can lead to dependence and withdrawal. This New York–focused guide covers symptoms, when to consider medical detox, and how to plan safe, evidence-informed care—plus statewide resources and testing options.

What Is 7-OH & How Does It Relate to Detox?

7-OH in context: A potent kratom alkaloid associated with...

Educational overview on kratom’s potent alkaloid 7-hydroxymitragynine (7-OH) and its opioid-like withdrawal potential. Highlights the rise of kratom dependence cases across New York, clinical findings from peer-reviewed literature, and emerging success of buprenorphine-based treatment protocols. Includes key facts, U.S. regulatory context, and resource links from NIDA, SAMHSA, and FDA to support safe detox and recovery practices.

Educational overview of kratom addiction and severe withdrawal emerging in Long Island and New York, detailing 7-OH risks, FDA and local laws, and safe pathways to treatment.

In recent years, the rise of 7-hydroxymitragynine (7-OH) — one of the most potent alkaloids found in kratom — has raised serious concerns across New York State. While kratom is often marketed as a “natural” supplement, research shows that 7-OH has powerful opioid-like effects, leading to dependence, withdrawal, and even overdose when misused.

 

 

Why Accessibility Is a Public Health Issue

 

 

New York lawmakers are beginning to respond to this growing threat. In 2025, Senate Bill S7379 was introduced, proposing to add kratom to the list of Schedule I controlled substances under state law...