The high dropout rate (75%) in opioid use disorder (OUD) treatment among women and racial/ethnic minorities in the United States necessitates a better knowledge of the factors that contribute to treatment success. While therapy and medication for OUD are considered the top standard of care in substance use disorder (SUD) treatment, many people with OUD receive just counseling or methadone-only therapies. This study compares gender inequalities in methadone-based treatment plan progress to counseling-based programs in one of the biggest SUD treatment systems in the United States.

The...

In response to the rising efficacy of the illicit opioid drug supply and often observed delays in access to follow-up therapy, emergency departments (EDs) occasionally utilize a high-dose buprenorphine induction method for the treatment of opioid use disorder (OUD). The objective of this study is to investigate the safety and tolerability of high-dose (>12 mg) buprenorphine induction for patients with OUD presenting to an ED.

Data were manually extracted from electronic health records for all ED patients with OUD treated with buprenorphine at a single, urban, safety-net hospital in Oakland...