Background
A non-medicalized safer supply model called a “Compassion Club” has recently been evaluated. The model involved providing rigorously tested and accurately labeled illicit substances to members at cost. Operating for 14 months in Vancouver's Downtown Eastside, the initiative aimed to explore the effects and feasibility of this approach among individuals at risk of fatal overdose.

Methods
At the one-year mark, 43 club members completed a survey for this cross-sectional analysis. Descriptive statistics were used to assess the perceived impact of membership on factors like drug use...

Addiction and obesity share similar neurological pathways, both linked to compulsive behaviors and the brain's reward system. Research has highlighted the potential of GLP-1 receptor agonists, originally developed for diabetes, to help manage both appetite and addictive cravings. These medications, such as semaglutide, may regulate addictive behaviors by influencing reward circuits in the brain. However, they come with potential side effects, and their long-term effects are still under investigation.

In addition, a new compound, 5-Methoxy-2-aminoindane (MEAI), is being researched for its...

Researchers at Virginia Commonwealth University (VCU) have developed a new version of a medication for opioid use disorder that could offer longer-lasting treatment. Current medications for opioid addiction often require daily doses, but the new formulation of nor-levo-alpha-acetylmethadol (nor-LAAM) is designed to be taken once a month or less frequently. This long-acting medication has shown promise in reducing opioid use and withdrawal symptoms in rodent models. The goal is to provide an alternative to existing treatments like methadone and buprenorphine, which come with barriers such as...

Few studies have looked into how cannabis use during pregnancy affects the development of disruptive behavioral disorders (DBDs) in children, often using small sample sizes and self-reported data. This study aimed to understand the link between maternal cannabis use disorder (CUD) during pregnancy and after childbirth, and the risk of DBDs in children. We used health data from New South Wales, Australia, for children born between 2003 and 2005. We compared children whose mothers had CUD to those whose mothers did not, and assessed the risk of DBDs in these children. Both CUD and DBDs were...

This briefing paper aims to raise awareness about the widespread and severe impact of GBV on women and people of diverse gender identity and expression who use drugs, as well as the strong connection between GBV and the HIV epidemic within these populations. It outlines practical responses that harm reduction providers and allied services can adopt to address violence and support the rights and health of these groups. The paper also demonstrates how a gender-responsive approach to drug use can improve outcomes for women and gender-diverse individuals by reducing harm, increasing access to...

The National Survey of Substance Use and Mental Health Services (N-SUMHSS) is a voluntary, annual survey that collects data from all active substance use and mental health treatment facilities across the United States, its territories, and Washington D.C. The annual report provides valuable insights into key operational characteristics of these treatment facilities, including the use of pharmacotherapies, availability of language assistance services, and the provision of suicide prevention assistance. This comprehensive survey helps to inform policymakers, researchers, and service providers on...

A study was conducted to examine how patterns of alcohol and cannabis use are associated with bystander intervention in situations involving the risk of sexual and relationship violence among college students. Researchers aimed to explore whether students' substance use influenced their awareness of risky situations (referred to as bystander opportunities) and their likelihood of taking action (bystander behaviors). Two key hypotheses guided this investigation: the first being that the frequency of bystander opportunities would vary depending on the students’ patterns of alcohol and cannabis...

Conducted annually, the National Survey on Drug Use and Health (NSDUH) provides nationally representative data on the use of tobacco, alcohol, and drugs; substance use disorders; mental health issues; and receipt of substance use and mental health treatment among the civilian, noninstitutionalized population aged 12 or older in the United States. NSDUH estimates allow researchers, clinicians, policymakers, and the general public to better understand and improve the nation’s behavioral health. These reports and detailed tables present national estimates from the 2023 National Survey on Drug Use...

Over the last 3 decades, there have been several fluctuations in opioid use patterns and prevalence estimates in the United States. The predominant opioid involved in overdose deaths shifted from prescription opioids in the 1990’s and early 2000’s, to heroin in 2010, and to synthetic opioids like fentanyl in 2013. Recent estimates suggest that about 70% of drug overdose deaths involve synthetic opioids other than methadone, with fentanyl accounting for the majority of these deaths. Since 2015, there has also been a steady increase in deaths involving both fentanyl and stimulants.

This...

Background

Since 1996, an urban community-based organisation whose primary mission is to serve diverse94 and emerging community health needs has provided screening, testing, overdose prevention and training, referrals, and access to treatment for substance use disorders (SUD) and communicable diseases such as HIV through its Life Points harm reduction program.

Methods

As a partner in a State survey in 2021, the community organisation recruited a convenience sample of people who use drugs to participate in a survey focused on their substance use, healthcare, and barriers to SUD services...

Specific patterns of substance use have been found to correlate with an elevated risk of suicidal thoughts, attempts, and mortality by suicide. However, this relationship is multifaceted and influenced by various intersecting factors, including the type and quantity of substances consumed, as well as biological and social determinants. The Canadian Centre on Substance Use and Addiction, in collaboration with the Mental Health Commission of Canada, presents a comprehensive examination of these factors in their latest report titled "Intersections of Substance Use and Suicide: Evidence and Key...

Background

Lesbian, gay, bisexual, transgender, queer, and other LGBTQ populations (LGBTQ+; e.g., asexual individuals) have higher rates of substance use (SU) and disorders (SUD) compared to heterosexual and cisgender populations. Such disparities can be attributed to minority stress, including stigma and discrimination in healthcare settings. LGBTQ+-affirming SU treatment and related services remain limited. The purpose of this exploratory qualitative descriptive study was to characterise LGBTQ+ people’s experiences in SU services and recommendations for LGBTQ+- affirming care.

Methods

We...

Background
Data concerning driving under the influence of alcohol (DUIA) are frequently characterised by their lack of availability, accuracy, or reliability. This inherent limitation poses challenges in the examination of the influence of alcohol policies on road traffic outcomes. The study pursued a dual objective:

1) delineating the methodologies employed in evaluating road traffic outcomes attributable to alcohol policies in instances where DUIA data are absent, and

2) scrutinising the impact of alcohol policies under conditions of missing DUIA data.

Methods
A scoping review was...