Young adult polysubstance use trajectories and later non-prescribed opioid use and drug use disorder symptoms: A propensity score-matched analysis

Source:

Harton, M. R., Agley, J., Seo, D., Zoh, R. S., & Parker, M. A. (2026). Young adult polysubstance use trajectories and later non-prescribed opioid use and drug use disorder symptoms: A propensity score-matched analysis. Drug and Alcohol Dependence Reports, 21, 100479. https://doi.org/10.1016/j.dadr.2026.100479

Highlights

• •Five young adult polysubstance use trajectories were identified.
• •High-use trajectories predicted later non-prescribed opioid use.
• •High-use trajectories predicted adult drug use disorder symptoms.
• •Associations persisted after propensity score weighting.