Substance Use Screening Tools

Substance use screening tools vary by purpose, setting, and depth, ranging from brief population‑level screens to more comprehensive assessments used in clinical care. Widely used instruments support early identification across healthcare, community, and digital settings, while more targeted tools focus on specific substances or populations and others extend into assessment and treatment planning. Below are commonly used screening tools for alcohol, drug, and multi‑substance use to help practitioners, researchers, and policymakers select appropriate options for early detection, brief intervention, and referral to care, with links to original sources where available.

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Simple Screening Instrument for Substance Abuse (SSI-SA)
Accessible data	Settings	Primary Substances
Treatment entry screening and triage Drug-related crime & justice	Criminal justice settings Clinical and specialist treatment services	Multi-substance use

Addiction Severity Index (ASI)
Accessible data	Settings	Primary Substances
Clinical assessment and treatment planning Monitoring treatment outcomes	Clinical and specialist treatment services	Multi-substance use

Global Appraisal of Individual Needs : Short Screener (GAIN-SS)
Accessible data	Settings	Primary Substances
Mental health and co-occurring condition screening Clinical assessment and treatment planning	Clinical and specialist treatment services Community services	Multi-substance use

Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT)
Accessible data	Settings	Primary Substances
Youth and adolescent risk identification	Schools and adolescent services	Alcohol Cannabis Multi-substance use

Global Appraisal of Individual Needs (Full) (GAIN)
Accessible data	Settings	Primary Substances
Clinical assessment and treatment planning Monitoring treatment outcomes Mental health and co-occurring condition screening	Clinical and specialist treatment services Research and epidemiological studies	Multi-substance use

Alcohol Use Disorders Identification Test (AUDIT)
Accessible data	Settings	Primary Substances
Early detection and brief intervention	General population screening Clinical and specialist treatment services	Alcohol

Substance Use Brief Screen (SUBS)
Accessible data	Settings	Primary Substances
Early detection and brief intervention	Primary care	Multi-substance use

Maudsley Addiction Profile (MAP)
Accessible data	Settings	Primary Substances
Monitoring treatment outcomes	Clinical and specialist treatment services	Multi-substance use

Alcohol Use Disorders Identification Test (AUDIT-C)
Accessible data	Settings	Primary Substances
Early detection and brief intervention	Primary care	Alcohol

Single-Item Screening Questions (SISQ)
Accessible data	Settings	Primary Substances
Early detection and brief intervention	General population screening	Multi-substance use

European Addiction Severity Index (EuropASI)
Accessible data	Settings	Primary Substances
Clinical assessment and treatment planning Monitoring treatment outcomes	Clinical and specialist treatment services Research and epidemiological studies	Multi-substance use

Cut down, Annoyed, Guilty, Eye-opener (CAGE)
Accessible data	Settings	Primary Substances
Early detection and brief intervention	General population screening	Alcohol

Screening to Brief Intervention (S2BI)
Accessible data	Settings	Primary Substances
Youth and adolescent risk identification Early detection and brief intervention	Schools and adolescent services	Alcohol Cannabis Multi-substance use

Fagerström Test for Nicotine Dependence (FTND)
Accessible data	Settings	Primary Substances
Tobacco and nicotine dependence assessment	Primary care Clinical and specialist treatment services	Tobacco / nicotine

Fast Alcohol Screening Test (FAST)
Accessible data	Settings	Primary Substances
Early detection and brief intervention	Emergency departments Primary care	Alcohol

Brief Screener for Tobacco, Alcohol, and other Drugs (BSTAD)
Accessible data	Settings	Primary Substances
Youth and adolescent risk identification Early detection and brief intervention	Schools and adolescent services	Tobacco / nicotine Alcohol Cannabis Multi-substance use

Heaviness of Smoking Index (HIS)
Accessible data	Settings	Primary Substances
Tobacco and nicotine dependence assessment	Clinical and specialist treatment services Primary care	Tobacco / nicotine

Michigan Alcohol Screening Test (MAST)
Accessible data	Settings	Primary Substances
Clinical assessment and treatment planning	Clinical and specialist treatment services	Alcohol

Personal Experience Screening Questionnaire (PESQ)
Accessible data	Settings	Primary Substances
Youth and adolescent risk identification	Schools and adolescent services	Multi-substance use

Alcohol, Smoking and Substance Involvement Screening Test (ASSIST)
Accessible data	Settings	Primary Substances
Early detection and brief intervention Treatment entry screening and triage	General population screening Primary care	Multi-substance use Alcohol Tobacco / nicotine Cannabis Opioids Stimulants

Risk Assessment Battery (RAB)
Accessible data	Settings	Primary Substances
HIV and substance-related behavioural risk	Community services High-risk population services	Opioids Injection-related risk behaviours

Short Michigan Alcohol Screening Test (SMAST)
Accessible data	Settings	Primary Substances
Clinical assessment and treatment planning	Clinical and specialist treatment services	Alcohol

Parents, Partner, Past, Pregnancy Plus (4Ps Plus)
Accessible data	Settings	Primary Substances
Pregnancy-related substance use screening	Pregnancy and maternal care	Multi-substance use

Alcohol, Smoking and Substance Involvement Screening Test : Lite (ASSIST-Lite)
Accessible data	Settings	Primary Substances
Early detection and brief intervention	General population screening Primary care	Multi-substance use

Tolerance, Worried, Eye-opener, Amnesia, K/Cut down (TWEAK)
Accessible data	Settings	Primary Substances
Pregnancy-related substance use screening	Pregnancy and maternal care	Alcohol

Mini International Neuropsychiatric Interview : Substance Use Module (MINI (SU module))
Accessible data	Settings	Primary Substances
Mental health and co-occurring condition screening Clinical assessment and treatment planning	Clinical and specialist treatment services	Substance use linked to mental health conditions

Cut down, Annoyed, Guilty, Eye-opener : Adapted to Include Drugs (CAGE-AID)
Accessible data	Settings	Primary Substances
Early detection and brief intervention	General population screening	Alcohol Illicit drugs Multi-substance use

Tolerance, Annoyed, Cut down, Eye-opener (T-ACE)
Accessible data	Settings	Primary Substances
Pregnancy-related substance use screening	Pregnancy and maternal care	Alcohol

Kessler Psychological Distress Scale (with substance modules) (K10 (+ SU modules))
Accessible data	Settings	Primary Substances
Mental health and co-occurring condition screening	General population screening Community services	Substance use linked to mental health conditions

Tobacco, Alcohol, Prescription medication, and other Substance use tool (TAPS)
Accessible data	Settings	Primary Substances
Early detection and brief intervention Treatment entry screening and triage	Primary care	Multi-substance use Prescription medications Opioids Tobacco / nicotine

Drug Use Disorders Identification Test (DUDIT)
Accessible data	Settings	Primary Substances
Clinical assessment and treatment planning	Clinical and specialist treatment services	Illicit drugs Cannabis Stimulants Opioids

Texas Christian University Drug Screen (TCU Drug Screen)
Accessible data	Settings	Primary Substances
Treatment entry screening and triage Drug-related crime & justice	Criminal justice settings	Illicit drugs Cannabis Stimulants Opioids

Drug Abuse Screening Test (DAST)
Accessible data	Settings	Primary Substances
Clinical assessment and treatment planning	Clinical and specialist treatment services Research and epidemiological studies	Illicit drugs Cannabis Stimulants Opioids