Opioid dependence is associated with substantial health and social burdens, and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for people who receive this treatment. Methadone and buprenorphine are common...
Alcohol use disorders (AUD) are prevalent and often go untreated. Patients are commonly screened for AUD in primary care, but existing treatment programs are failing to meet demand. Digital therapeutics include novel...
Microglia participates in the modulation of pain signaling. The activation of microglia is suggested to play an important role in affective disorders that are related to a dysfunction of the mesocorticolimbic system (MCLS) and are...
The crisis of opioid use puts a strain on resources in the United States and worldwide. There are 3 US Food and Drug Administration–approved medications for treatment of opioid use disorder: methadone, buprenorphine...
Cocaine is an addictive stimulant drug that originates from the leaves of the coca plant, which is indigenous to South America. The drug's effects include heightened alertness, attention, and energy, as well as feelings of euphoria and...
Substance misuse among young people is one of the most public concerns in global health. This study set out to explore treatment barriers among young people in Zimbabwe.
Data was collected through interviews with 30 participants
The study...
Objective: To better understand current developments in the treatment of stimulant use.
Background: Stimulant drugs are second only to cannabis as the most widely used class of illicit drug globally, accounting for 68 million past-year...
Question What treatments for cocaine use disorder are associated with objective reductions in cocaine use among adults?
Findings In this meta-analysis of 157 clinical trials comprising 402 treatment groups and 15 842...
Abstract
Importance Information about the trend in illicit substance ingestions among young children during the pandemic is limited.
Objectives To assess immediate and sustained changes in overall illicit substance ingestion rates among...
