The negative allosteric modulator of mGluR5, MPEP, enhances the reinstatement of the conditioned preference induced with cocaine priming
In Chile, the consumption of Cocaine Base Paste (CBP), a highly toxic and addictive substance, has become a serious medical and social problem in the poorest areas of the country. This substance is smoked and quickly provokes in the user the compulsive desire to continue using it, as well as to great difficulty in stopping consumption, mainlydue to the withdrawal symptoms that it generates in the user.
Introduction: People who consume heroin and cocaine have increased sexual activity, risk behaviours associated with injection and inconsistent condom use, which would increase the risk of sexually transmitted infections and the presence of HIV.
This valuable document, Sonia Alda Mejías presents an approach to the analysis of illegal flows of trafficking in cocaine. It does this through a vision that provides some of the key aspects of the analysis of transnational criminal networks, which form part of a world of hiperglobalizado.
Introduction: Cocaine is an independent cerebrovascular risk factor both for ischaemic and haemorrhagic events, above all among persons under 55 years of age.
The present compendium of chemical characterization of Fumables cocaine is part of the cocaine Fumables project in Argentina, Brazil, Chile, Paraguay and Uruguay, coordinated by the Inter-American Observatory on drugs of the Inter-American Commission for the Control of the abuse of drugs of the Secretariat for Multidimensional Security of the Organization of American States (OID-SSM-CICAD-OAS) with funding from INL-USA.