randomized controlled trial

Abstract Importance Cocaine use disorder is a serious public health problem and no medications have been proven effective for its treatment. Objective To evaluate psilocybin in the treatment of cocaine use disorder. It was hypothesized that...

Source: Carpenter MJ, Smith TT, Wahlquist AE, et al. Medication Samples and Smoking Cessation Among Adults: A Randomized Clinical Trial. JAMA Netw Open. 2026;9(5):e2611418. doi:10.1001/jamanetworkopen.2026.11418 Abstract Importance Smoking...

INTRODUCTION: Longitudinal prevention research in adolescents often involves sensitive data collection, necessitating anonymity. Self-Generated Identification Codes (SGICs) have emerged as a tool for linking anonymous data while preserving...

Abstract This study aimed to evaluate the effectiveness of the drug and violence resistance educational program (PROERD) on short-term secondary outcomes, such as intentions to use drugs, attitudes toward drugs, school experience, and life...

Background: Depressive disorders and problematic drinking often co-occur, also among young adults. These co-occurring conditions are associated with various negative health outcomes compared to both conditions alone. Early intervention by...

ABSTRACT Background: Due to a resurgent debate on the misuse of P values, the Journal of Medical Internet Research is hosting a standing theme issue inviting the reanalysis of (primarily digital health) trial data using a Bayesian framework...

ABSTRACT Background: Applying theory to the design and evaluation of interventions is likely to increase effectiveness and improve the evidence base from which future interventions are developed, though few interventions report this...

Abstract Background: Depression in the workplace creates a significant burden on employees and employers in terms of lost productivity and related costs. myStrength provides a robust, holistic web- and mobile-based solution empowering users...