Incidence and Progression of Alcohol-Associated Liver Disease After Medical Therapy for Alcohol Use Disorder

Source:

Vannier AGL, Shay JES, Fomin V, et al. Incidence and Progression of Alcohol-Associated Liver Disease After Medical Therapy for Alcohol Use Disorder. JAMA Netw Open. 2022;5(5):e2213014. doi:10.1001/jamanetworkopen.2022.13014

Key Points

Question  Are patients with alcohol use disorder (AUD) who receive medical addiction therapy less likely to develop alcohol-associated liver disease (ALD)?

Findings  In this cohort study of 9635 patients with AUD, those who received medical addiction therapy had a significantly lower risk of developing ALD, whereas patients with cirrhosis who received medical addiction therapy had a significantly lower incidence of hepatic decompensation.

Meaning  Findings from this study suggest an association between use of medical addiction therapy for AUD and decreased incidence and progression of ALD.