Jose Luis Vazquez Martinez

Cost-Effectiveness of Smoking Cessation Interventions Integrated Into Lung Cancer Screening

Jose Luis Vazquez Martinez -

Source:

Cao P, Smith L, Tian E, et al. Cost-Effectiveness of Smoking Cessation Interventions Integrated Into Lung Cancer Screening. JAMA Netw Open. 2026;9(9):e2633630. doi:10.1001/jamanetworkopen.2026.33630

 

Key Points

Question  What is the cost-effectiveness of integrating smoking cessation interventions with varying intensity into lung cancer screening programs in the US?

Findings  In this economic evaluation of 2520 individuals enrolled in 4 randomized clinical trials, trial data were projected over a lifetime horizon using an established microsimulation model. All cessation interventions combined with lung cancer screening were cost-saving vs screening alone, and high-intensity pharmacotherapy and counseling were associated with the greatest health gains, with an incremental cost-effectiveness ratio of $991 per quality-adjusted life-year.

Meaning  The findings of this study suggest that integrating evidence-based smoking cessation interventions into lung cancer screening programs may represent a highly cost-effective use of health care resources.