The range of medical, psychological, and social services designed to help individuals reduce or stop substance use and manage substance use disorders. Treatment may include assessment, counselling and behavioural therapies, medication-assisted treatment, withdrawal management, and support for co-occurring mental or physical health conditions. Effective treatment is typically person-centred and evidence-informed, and may be provided in outpatient, community, or residential settings. Treatment aims to improve health and functioning, reduce substance-related harms, and support individuals in moving toward recovery and long-term wellbeing.
Treatment
Identification of Novel Signal Transduction, Immune Function, and Oxidative Stress Genes and Pathways by Topiramate for Treatment of Methamphetamine Dependence Based on Secondary Outcomes
Background: Topiramate (TPM) is suggested to be a promising medication for treatment of methamphetamine (METH) dependence, but the molecular basis remains to be elucidated. Methods: Among 140 METH-dependent participants randomly assigned to...
Gender and Age Effects on the Trajectory of Depression in Opioid Users during Methadone Maintenance Treatment
Introduction: Both heroin use and depression are significant health problems. Methadone maintenance treatment (MMT) can be of great benefit to heroin users. However, changes in the level of depression in heroin users during MMT are not...
Effect of Exercise versus Cognitive Behavioural Therapy or no Intervention on Anxiety, Depression, Fitness and Quality of Life in Adults with Previous Methamphetamine Dependency
Abstract Background Methamphetamine (MA) is a highly addictive psychostimulant used by approximately 52 million people worldwide. Chronic MA abuse leads to detrimental physiological and neurological changes, as well as increases in anxiety...
Granulocyte-Colony Stimulating Factor Controls Neural and Behavioral Plasticity in Response to Cocaine
Cocaine addiction is characterized by dysfunction in reward-related brain circuits, leading to maladaptive motivation to seek and take the drug. There are currently no clinically available pharmacotherapies to treat cocaine addiction...
Effectiveness Bank Matrix Cell: Engaging Organisations, Engaging Treatment
Key studies on the how the functioning of treatment organisations affects the implementation and impacts of improvements. Introduces two high-quality, evidence-based US quality improvement resources, and asks what makes a treatment service...
Feasibility of Implementing a Culturally Adapted Parenting Intervention for Karen Refugee Caretakers in the U.S.
Elizabeth A Wieling , Jaime Ballard, Christopher Mehus, Damir Utrzan Introduction: Increasing numbers of children are fleeing to the United States after exposure to war and conflict. Children exposed to war have high rates of negative...
Development of a Smartphone App-Based Messaging Intervention to Encourage HIV Self-Testing in Hefei, China
Cui Yang , Ashley Perez, Don Operario, Hongo Zhang, Nickolas Zaller Introduction: Research in China has found that MSM avoid HIV testing at clinics or public health departments due in part to stigma and fear of disclosure of their MSM...
Going to Scale with Parent Training in Norway: What Have We Found and Where Should We Go?
John Kjøbli To scale up evidence-based interventions for the prevention and treatment of child conduct problems in primary care settings, the program Early Initiatives for Children at Risk (Norwegian acronym; TIBIR) was developed. The...
Financial Capability Program and Condom Use among Sexually-Active Youth in the Ghana Youthsave Project
Rainier Masa , Gina Chowa Background: Despite high level of knowledge about condoms, condom use remains low among sexually active youth globally, including Ghana. Although interventions that promote condom use have been implemented, few...
Most-Read Knowledge Share Articles of 2017
Here is a selection of the most-read Knowledge Share articles of 2017. These are the articles that captivated our members most.