Research

The negative allosteric modulator of mGluR5, MPEP, enhances the reinstatement of the conditioned preference induced with cocaine priming

Citation
Manzanedo, C., Mateos-García, A., Miñarro, J., & Arenas, M. (2019). El modulador alostérico negativo de los mGluR5, MPEP, potencia la reinstauración de la preferencia condicionada inducida con priming de cocaína. Adicciones, 32(3), 193-201. doi:http://dx.doi.org/10.20882/adicciones.1156
summary

A Systematic Review of Evidence-Based Practice Implementation in Drug and Alcohol Settings: Applying the Consolidated Framework for Implementation Research Framework

Citation
Louie, E., Barrett, E.L., Baillie, A. et al. A systematic review of evidence-based practice implementation in drug and alcohol settings: applying the consolidated framework for implementation research framework. Implementation Sci 16, 22 (2021). https://doi.org/10.1186/s13012-021-01090-7
Publication Date

Abstract

Background

There is a paucity of translational research programmes to improve implementation of evidence-based care in drug and alcohol settings. This systematic review aimed to provide a synthesis and evaluation of the effectiveness of implementation programmes of treatment for patients with drug and alcohol problems using the Consolidated Framework for Implementation Research (CFIR).

An Autophagy-Related Protein Becn2 Regulates Cocaine Reward Behaviors in the Dopaminergic System

Citation
Kim, Y. J., Kong, Q., Yamamoto, S., Kuramoto, K., Huang, M., Wang, N., ... & He, C. (2021). An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system. Science Advances, 7(8), eabc8310.
Publication Date

Abstract

Drug abuse is a foremost public health problem. Cocaine is a widely abused drug worldwide that produces various reward-related behaviors. The mechanisms that underlie cocaine-induced disorders are unresolved, and effective treatments are lacking.

Projected Estimates of Opioid Mortality After Community-Level Interventions

Citation
Linas BP, Savinkina A, Madushani RWMA, et al. Projected Estimates of Opioid Mortality After Community-Level Interventions. JAMA Netw Open. 2021;4(2):e2037259. doi:10.1001/jamanetworkopen.2020.37259
Publication Date
Abstract

Importance: The United States is experiencing a crisis of opioid overdose. In response, the US Department of Health and Human Services has defined a goal to reduce overdose mortality by 40% by 2022.

Association of Recreational Cannabis Legalization With Maternal Cannabis Use in the Preconception, Prenatal, and Postpartum Periods

Citation
Skelton KR, Hecht AA, Benjamin-Neelon SE. Association of Recreational Cannabis Legalization With Maternal Cannabis Use in the Preconception, Prenatal, and Postpartum Periods. JAMA Netw Open. 2021;4(2):e210138. doi:10.1001/jamanetworkopen.2021.0138
Publication Date
Abstract

Importance: Recent studies have revealed increases in population-level cannabis use after legalization of recreational cannabis. However, the association of cannabis legalization with maternal cannabis use during important life stages remains unknown.

Smoking Cessation for Improving Mental Health- Cochrane Review

Citation
Taylor, G. M., McNeill, A., Farley, A., Lindson, N., Aveyard, P., & Group, C. T. A. (2020). Smoking cessation for improving mental health. The Cochrane Database of Systematic Reviews, 2020(1).

People with mental health issues are more likely to smoke compared to the general population. They are also more likely to experience severe withdrawals and are less responsive to treatment. Indeed, some people believe that quitting smoking can worsen individuals mental health difficulties.

Machine Learning Assessment of Early Life Factors Predicting Suicide Attempt in Adolescence or Young Adulthood

Citation
Navarro MC, Ouellet-Morin I, Geoffroy M, et al. Machine Learning Assessment of Early Life Factors Predicting Suicide Attempt in Adolescence or Young Adulthood. JAMA Netw Open. 2021;4(3):e211450. doi:10.1001/jamanetworkopen.2021.1450
Publication Date

Abstract

Importance: Although longitudinal studies have reported associations between early life factors (ie, in-utero/perinatal/infancy) and long-term suicidal behavior, they have concentrated on 1 or few selected factors, and established associations, but did not investigate if early-life factors predict suicidal behavior.

Alcohol Policy in Chile

Citation
Peña, S., Sierralta, P., Norambuena, P., Leyton, F., Pemjean, A., & Román, F. (2020). Alcohol policy in Chile: a systematic review of policy developments and evaluations. Addiction.

Chile has one of the highest rates of alcohol use per capita in the Americas. Policy to reduce alcohol-related harm is often up against resistance from alcohol industry, policymakers and the public.

This review, published in the Journal of Addiction, provides an analysis of enacted and proposed laws of national alcohol policies in Chile.

Cultural Differences in Tweeting about Drinking across the US

Citation
Giorgi, S., Yaden, D. B., Eichstaedt, J. C., Ashford, R. D., Buffone, A. E., Schwartz, H. A., ... & Curtis, B. (2020). Cultural differences in Tweeting about drinking across the US. International journal of environmental research and public health, 17(4), 1125.
Publication Date

Abstract

Excessive alcohol use in the US contributes to over 88,000 deaths per year and costs over $250 billion annually. While previous studies have shown that excessive alcohol use can be detected from general patterns of social media engagement, we characterized how drinking-specific language varies across regions and cultures in the US.

Combinations of Drinking Occasion Characteristics Associated with Units of Alcohol Consumed among British Adults: An Event‐Level Decision Tree Modeling Study

Citation
Stevely, A. K., Holmes, J., & Meier, P. S. (2021). Combinations of Drinking Occasion Characteristics Associated with Units of Alcohol Consumed among British Adults: An Event‐Level Decision Tree Modeling Study. Alcoholism: Clinical and Experimental Research.
Publication Date

Abstract

Background

Alcohol consumption is influenced by the characteristics of drinking occasions, for example, location, timing, or the composition of the drinking group. However, the relative importance of occasion characteristics is not yet well understood.

A US national randomized study to guide how best to reduce stigma when describing drug‐related impairment in practice and policy

Citation
Kelly, J. F., Greene, M. C., and Abry, A. (2020) A US national randomized study to guide how best to reduce stigma when describing drug‐related impairment in practice and policy. Addiction, https://doi.org/10.1111/add.15333.
Publication Date

Abstract

Association of Cannabis Retailer Proximity and Density With Cannabis Use Among Pregnant Women in Northern California After Legalization of Cannabis for Recreational Use

Citation
Young-Wolff KC, Adams SR, Padon A, et al. Association of Cannabis Retailer Proximity and Density With Cannabis Use Among Pregnant Women in Northern California After Legalization of Cannabis for Recreational Use. JAMA Netw Open. 2021;4(3):e210694. doi:10.1001/jamanetworkopen.2021.0694
Publication Date

This cross-sectional study found that, after the state-level legalization of cannabis for recreational use in California, greater retail availability was associated with higher odds of cannabis use among pregnant women; these results were consistent with a dose-response association.

Office-Based Addiction Treatment Retention and Mortality Among People Experiencing Homelessness

Citation
Fine DR, Lewis E, Weinstock K, Wright J, Gaeta JM, Baggett TP. Office-Based Addiction Treatment Retention and Mortality Among People Experiencing Homelessness. JAMA Netw Open. 2021;4(3):e210477. doi:10.1001/jamanetworkopen.2021.0477
Publication Date
Abstract

Importance  People experiencing homelessness have been disproportionately affected by the opioid overdose crisis. To mitigate morbidity and mortality, several office-based addiction treatment (OBAT) programs designed for this population have been established across the US, but studies have not yet evaluated their outcomes.

 

Assessment of Annual Cost of Substance Use Disorder in US Hospitals

Citation
Peterson C, Li M, Xu L, Mikosz CA, Luo F. Assessment of Annual Cost of Substance Use Disorder in US Hospitals. JAMA Netw Open. 2021;4(3):e210242. doi:10.1001/jamanetworkopen.2021.0242
Publication Date
Abstract

Importance  A persistently high US drug overdose death toll and increasing health care use associated with substance use disorder (SUD) create urgency for comprehensive estimates of attributable direct costs, which can assist in identifying cost-effective ways to prevent SUD and help people to receive effective treatment.

 

With Crisis Comes Opportunity: Unanticipated Benefits Resulting from Pivots to Take-Home Naloxone (THN) Programs during the COVID-19 Pandemic

Citation
Courser, M. W., & Raffle, H. (2021). With crisis comes opportunity: Unanticipated benefits resulting from pivots to take-home naloxone (THN) programs during the COVID-19 pandemic. Journal of Substance Abuse Treatment, 122, 108220.

Abstract

The COVID-19 pandemic resulted in stay-at-home orders, which presented a significant challenge to the design and operation of an essential harm-reduction strategy in the opioid epidemic: community-based, take-home naloxone (THN) programs. This commentary describes how four rural and/or Appalachian communities quickly pivoted their existing THN programs to respond to community need.

Supportive Alternate Site Provision of Buprenorphine: Overcoming Barriers and Improving Patient Outcomes

Citation
Khan, A., Khan, Q., & Kolb, E. (2021). Supportive alternate site provision of buprenorphine: Overcoming barriers and improving patient outcomes. Journal of Substance Abuse Treatment, 123, 108256.

Abstract

Background

Improving access to medications for opioid use disorder (MOUD) is a national priority; however, these efforts commonly focus on the provider. Access to buprenorphine through retail pharmacies and stigma associated with filling prescriptions for MOUD pose additional barriers for patients when embarking on their road to recovery.

Take-Home Dosing Experiences among Persons Receiving Methadone Maintenance Treatment during COVID-19

Citation
Figgatt, M. C., Salazar, Z., Day, E., Vincent, L., & Dasgupta, N. (2021). Take-home dosing experiences among persons receiving methadone maintenance treatment during COVID-19. Journal of Substance Abuse Treatment, 123, 108276.

Abstract

Purpose

Methadone maintenance treatment is a life-saving treatment for people with opioid use disorders (OUD). The coronavirus pandemic (COVID-19) has introduced many concerns surrounding access to opioid treatment. In March 2020, the Substance Abuse and Mental Health Services Administration (SAMHSA) issued guidance allowing for the expansion of take-home methadone doses.

Consistency between Self-Reported Alcohol Consumption and Biological Markers among Patients with Alcohol Use Disorder – A Systematic Review

Citation
Nielsen, D. G., Andersen, K., Nielsen, A. S., Juhl, C., & Mellentin, A. (2021). Consistency between self-reported alcohol consumption and biological markers among patients with alcohol use disorder–a systematic review. Neuroscience & Biobehavioral Reviews.

ABSTRACT

Background

No systematic review has yet examined the consistency between self-reports of alcohol consumption and alcohol biomarkers among patients in treatment for alcohol use disorders (AUD). Therefore, we aimed to provide an overview of the consistency between self-reported alcohol intake and biomarkers among patients in treatment for AUD.

Recovery Community Centers: Characteristics of New Attendees and Longitudinal Investigation of the Predictors and Effects of Participation

Citation
Kelly, J. F., Fallah-Sohy, N., Cristello, J., Stout, R. L., Jason, L. A., & Hoeppner, B. B. (2021). Recovery community centers: Characteristics of new attendees and longitudinal investigation of the predictors and effects of participation. Journal of Substance Abuse Treatment, 124, 108287.
Publication Date

Abstract

Objective

Recovery community centers (RCCs) have expanded across the U.S., serving as social “recovery hubs” that increase recovery capital (e.g., employment, housing) by providing resources that clinical care does not provide. While research supports RCCs' general utility, little is known about new participants' characteristics, predictors of engagement, services used, and benefits derived.

Analysis of Active and Passive Tobacco Exposures and Blood Pressure in US Children and Adolescents

Citation
Levy RV, Brathwaite KE, Sarathy H, Reidy K, Kaskel FJ, Melamed ML. Analysis of Active and Passive Tobacco Exposures and Blood Pressure in US Children and Adolescents. JAMA Netw Open. 2021;4(2):e2037936. doi:10.1001/jamanetworkopen.2020.37936
Publication Date

Abstract

Importance: Hypertension is a leading cause of cardiovascular disease in adults; preclinical associations between hypertension and cardiovascular disease are seen in childhood. Nicotine is a known toxin, but its association with pediatric hypertension is unclear.

Effect of Cigarette Constituent Messages With Engagement Text on Intention to Quit Smoking Among Adults Who Smoke Cigarettes: A Randomized Clinical Trial

Citation
Goldstein AO, Jarman KL, Kowitt SD, et al. Effect of Cigarette Constituent Messages With Engagement Text on Intention to Quit Smoking Among Adults Who Smoke Cigarettes: A Randomized Clinical Trial. JAMA Netw Open. 2021;4(2):e210045. doi:10.1001/jamanetworkopen.2021.0045
Publication Date

Abstract

Importance: The US Food and Drug Administration (FDA) is required to communicate the risks of tobacco constituents to the public. Few studies have addressed how FDA media campaigns can effectively communicate about cigarette smoke constituents.

A Scoping Review of Factors that Influence Opioid Overdose Prevention for Justice-Involved Populations

Citation
Grella, C.E., Ostlie, E., Scott, C.K. et al. A scoping review of factors that influence opioid overdose prevention for justice-involved populations. Subst Abuse Treat Prev Policy 16, 19 (2021). https://doi.org/10.1186/s13011-021-00346-1
Publication Date

Abstract

Background

There is a high risk of death from opioid overdose following release from prison. Efforts to develop and implement overdose prevention programs for justice-involved populations have increased in recent years. An understanding of the gaps in knowledge on prevention interventions is needed to accelerate development, implementation, and dissemination of effective strategies.

Solution-Centered Therapy. A treatment option for alcohol dependence

Citation
Cordero, M., Cordero, R., Natera, G., & Caraveo, J. (2009). La Terapia Centrada en Soluciones. Una opción de tratamiento para la dependencia al alcohol. Salud Mental, 32(3), 223-230. Retrieved from http://www.revistasaludmental.mx/index.php/salud_mental/article/view/1287
Summary

In Mexico, excessive alcohol consumption represents one of the main public health challenges at the national level. Although there are a number of intervention strategies that seek to affect this problem, there is also a large gap as to whether such interventions are a causal factor in the change produced by the consumer and the way in which such change occurs after treatment.

Representation of Adverse Childhood Experiences Linked with Lower Public Stigma Towards People Who Use Drugs

Citation
Sumnall, H. R., Hamilton, I., Atkinson, A. M., Montgomery, C., & Gage, S. H. (2020). Representation of adverse childhood experiences is associated with lower public stigma towards people who use drugs: an exploratory experimental study. Drugs: Education, Prevention and Policy, 1-13.

Public stigma towards people who use substances can impact people seeking support and treatment outcomes. It can also influence how public health policy is shaped and accepted.

Researchers have been interested in understanding how people appraise substance use and whether attitudes can be changed if they frame substance use in different ways.

The Prevalence of Drug Use and Illicit Trafficking: A Descriptive Cross Sectional Study of Irregular Migrant Returnees in Nigeria

Citation
1. Ikenna Daniel Molobe , Oluwakemi Ololade Odukoya , The Prevalence of Drug Use and Illicit Trafficking: A Descriptive Cross Sectional Study of Irregular Migrant Returnees in Nigeria, Journal of Migration and Health (2021), doi: https://doi.org/10.1016/j.jmh.2021.100034
Publication Date

The prevalence of drug use and illicit trafficking: A descriptive cross sectional study of irregular migrant returnees in Nigeria

Ikenna Daniel Molobe (a , b)  Oluwakemi Ololade Odukoya (b , c)

Intelligence Quotient Decline Following Frequent or Dependent Cannabis Use in Youth: A Systematic Review and Meta-Analysis of Longitudinal Studies

Citation
Power, E., Sabherwal, S., Healy, C., O’Neill, A., Cotter, D., & Cannon, M. (2021). Intelligence quotient decline following frequent or dependent cannabis use in youth: a systematic review and meta-analysis of longitudinal studies. Psychological Medicine, 1-7.
Publication Date

cover

Substance Use and Antisocial Behaviour in Adolescence in the UK

The Millennium Cohort Study (MCS), is following the lives of around 19,000 young people born across England, Scotland, Wales and Northern Ireland.

In 2018-2019, the researchers from UCL analysed data from 10,000 17 years olds on their substance use – including drug taking, binge drinking and smoking – and antisocial behaviours – such as assault, shoplifting and vandalism.

Some of the key findings include:

Implementation of a Free Smoking-Cessation Program in a Lebanese Academic Medical Center

Citation
Romani, M., Nakkash, R., Jawhar, S., Salloum, R. G. (2020). Implementation of a free smoking-cessation program in a Lebanese academic medical center. Tobacco Induced Diseases, 18(September), 75. https://doi.org/10.18332/tid/125916
Publication Date

The American University of Beirut (AUB), with an affiliated tertiary medical center, developed one of the first smoking-cessation programs in the country in 2015 in response to an identified need within the university community. The program offers counseling to promote learning behavior modification and provides nicotine replacement therapy (NRT), including nicotine gum and patch.