Pharmacological Interventions

Abstract Abuse-deterrent opioid formulations have been suggested as one way to decrease the abuse, addiction, and overdose of orally prescribed opioids. Ten oral opioid formulations have received abuse-deterrent labeling by the U.S. Food...

Abstract Background Tobacco addiction is a complex, multicomponent phenomenon stemming from nicotine’s pharmacology and the user’s biology, psychology, sociology, and environment. After decades of public denial, the tobacco industry now...

Abstract Background and aims Behavioural and pharmacological support for smoking cessation improves the chances of success and represents a highly cost‐effective way of preventing chronic disease and premature death. There is a large number...

Abstract Diverse nicotine replacement therapy options may improve consumer usage. This study was conducted to establish the bioequivalence of a new cherry‐flavored mini lozenge with that of a currently marketed mint‐flavored mini lozenge...

Abstract Relapse after initially successful treatment is a significant problem facing the treatment of opioid dependence. Evidence suggests craving elicited by re‐exposure to drug cues may precipitate relapse. Attempts to identify neural...

Abstract Background The current lack of pharmacological treatments for cannabis use disorder (CUD) warrants novel approaches and further investigation of promising pharmacotherapy. We previously showed that nabiximols (27 mg/ml Δ9...

Abstract Background and Aims Considerable variation of outcome variables used to measure recovery in the gambling treatment literature has precluded effective cross-study evaluations and hindered the development of best-practice treatment...

Mental, neurological and substance (MNS) disorders are very common and represent a large burden of disease and disability around the world. There remains a wide gap between the capacity of health systems and resources, between what is...