naloxone

Overdose recognition and management: Reading list

Created by
ISSUP

According to the World Health Organisation, around half a million deaths each year are attributable to drug use. More than 70% of these deaths are related to opioids, with more than 30% of those deaths caused by overdose. Signs, symptoms, and management of an overdose differ depending on the situation and substance used. Below, is a list of research, publications, and tools on the subject of overdose recognition and management.

Evidence-Based Approaches to Opioid Overdose Recognition and Management: Share the Facts – Save Lives

Publication Date
To mark International Overdose Awareness Day on 31st of August 2021, the International Society of Substance Use Professionals (ISSUP), in collaboration with the United Nations Office on Drugs and Crime (UNODC) and the World Health Organization, presented an online event profiling naloxone programmes as a pathway for improving outcomes in the treatment of opioid dependence, overdose reduction, and saving lives. 

Evidence-Based Approaches to Opioid Overdose Recognition and Management: Share the Facts – Save Lives

London,
To mark International Overdose Awareness Day on 31st of August 2021, the International Society of Substance Use Professionals (ISSUP), in collaboration with the United Nations Office on Drugs and Crime (UNODC) and the World Health Organization, will present an online event profiling naloxone programmes as a pathway for improving outcomes in the treatment of opioid dependence, overdose reduction, and saving lives. 

Take-home naloxone

Created by
EMCDDA

Opioid overdose deaths can be prevented through timely administration of naloxone, a potent opioid antagonist drug that rapidly reverses the effects of opioid analgesics by binding to the opioid receptors in the central nervous system.

Because of its effectiveness, naloxone is used by emergency personnel worldwide.

Projected Estimates of Opioid Mortality After Community-Level Interventions

Citation
Linas BP, Savinkina A, Madushani RWMA, et al. Projected Estimates of Opioid Mortality After Community-Level Interventions. JAMA Netw Open. 2021;4(2):e2037259. doi:10.1001/jamanetworkopen.2020.37259
Publication Date
Abstract

Importance: The United States is experiencing a crisis of opioid overdose. In response, the US Department of Health and Human Services has defined a goal to reduce overdose mortality by 40% by 2022.

With Crisis Comes Opportunity: Unanticipated Benefits Resulting from Pivots to Take-Home Naloxone (THN) Programs during the COVID-19 Pandemic

Citation
Courser, M. W., & Raffle, H. (2021). With crisis comes opportunity: Unanticipated benefits resulting from pivots to take-home naloxone (THN) programs during the COVID-19 pandemic. Journal of Substance Abuse Treatment, 122, 108220.

Abstract

The COVID-19 pandemic resulted in stay-at-home orders, which presented a significant challenge to the design and operation of an essential harm-reduction strategy in the opioid epidemic: community-based, take-home naloxone (THN) programs. This commentary describes how four rural and/or Appalachian communities quickly pivoted their existing THN programs to respond to community need.

Opioid Overdose Reversal with Naloxone (Narcan, Evzio)

Created by
NIDA
Publication Date

What is Naloxone?

Naloxone is a medication designed to rapidly reverse opioid overdose. It is an opioid antagonist—meaning that it binds to opioid receptors and can reverse and block the effects of other opioids. It can very quickly restore normal respiration to a person whose breathing has slowed or stopped as a result of overdosing with heroin or prescription opioid pain medications.