Abstract: 

While the traditional complications of diabetes mellitus—such as cardiovascular disease—are well recognized, advances in treatment and increased life expectancy have revealed a new set of lesser-known complications that are becoming more prominent.

As mortality from vascular disease declines, conditions like cancer and dementia have emerged as leading causes of death among people with diabetes in several countries. In addition, growing evidence shows strong associations between diabetes and a range of comorbidities, including:

• Cognitive decline

• Functional disability

• ...

Objective:
Understanding that diabetes is a major risk factor for cardiovascular disease (CVD) may help increase diabetes screening and improve prevention efforts for CVD.

Overview:
The American Heart Association conducted an online survey across 50 countries to assess public awareness of the link between diabetes and CVD. The study looked at differences in awareness by sex, age, region, and country income level.

Key Findings:

• Out of 48,988 respondents, only 32.1% recognized diabetes as a major risk factor for CVD.

• Awareness was similar between men and women, but higher among older...

The International Drug Policy Academy (IDPA), established by the Council of Europe's Pompidou Group, is dedicated to enhancing the capabilities of professionals involved in drug policy and addiction services. With over 50 years of international cooperation and capacity building, the IDPA aims to bridge the gap between policy, research, and practice across various sectors, fostering the development of coherent and sustainable drug policies.  

Objectives of the IDPA

• Capacity Building: Strengthening the skills of professionals for effective design, management and evaluation of drug...

This brief examines the average alcohol consumption of people in Canada and where it falls within the risk zones outlined in Canada’s Guidance on Alcohol and Health (CGAH). The publication presents updated data on weekly drinking patterns by province, age, and sex, and assesses the extent to which people in Canada adhere to the CGAH guidelines. This report is intended to inform public health professionals, policy makers and researchers working to reduce alcohol-related harm.

Three Key Points You Will Find in the Document:

• People who drink alcohol in Canada consume an average of more than13...

CSUCH’s data visualisation tool can be used to estimate substance use trends across the country. The data helps inform programs, practices, and research to protect communities, save lives, and improve the well-being of people in Canada.

Spotlight: Top 3 causes of death due to substance use in Canada 

More than 200 people died each day due to substance use (SU) in 2020 (the latest year for which data are available). That works out to 73,994 deaths that year. The average age of death due to SU was 45 years. Tobacco use caused 63% (46,366) of SU-related deaths, followed by alcohol at 23%...

Background
Cognitive deficits are common in patients with substance use disorder (SUD) and can impact treatment outcomes. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is a widely used tool that could help identify cognitive impairments in SUD patients. This systematic review examines the RBANS’ effectiveness in detecting cognitive impairment in SUD patients and discusses knowledge gaps and the need for further research.

Methods
A systematic search was conducted in PsycINFO, Medline, and Cochrane databases to find relevant studies on the use of RBANS in SUD...

Background
A non-medicalized safer supply model called a “Compassion Club” has recently been evaluated. The model involved providing rigorously tested and accurately labeled illicit substances to members at cost. Operating for 14 months in Vancouver's Downtown Eastside, the initiative aimed to explore the effects and feasibility of this approach among individuals at risk of fatal overdose.

Methods
At the one-year mark, 43 club members completed a survey for this cross-sectional analysis. Descriptive statistics were used to assess the perceived impact of membership on factors like drug use...

Addiction and obesity share similar neurological pathways, both linked to compulsive behaviors and the brain's reward system. Research has highlighted the potential of GLP-1 receptor agonists, originally developed for diabetes, to help manage both appetite and addictive cravings. These medications, such as semaglutide, may regulate addictive behaviors by influencing reward circuits in the brain. However, they come with potential side effects, and their long-term effects are still under investigation.

In addition, a new compound, 5-Methoxy-2-aminoindane (MEAI), is being researched for its...

Researchers at Virginia Commonwealth University (VCU) have developed a new version of a medication for opioid use disorder that could offer longer-lasting treatment. Current medications for opioid addiction often require daily doses, but the new formulation of nor-levo-alpha-acetylmethadol (nor-LAAM) is designed to be taken once a month or less frequently. This long-acting medication has shown promise in reducing opioid use and withdrawal symptoms in rodent models. The goal is to provide an alternative to existing treatments like methadone and buprenorphine, which come with barriers such as...

Few studies have looked into how cannabis use during pregnancy affects the development of disruptive behavioral disorders (DBDs) in children, often using small sample sizes and self-reported data. This study aimed to understand the link between maternal cannabis use disorder (CUD) during pregnancy and after childbirth, and the risk of DBDs in children. We used health data from New South Wales, Australia, for children born between 2003 and 2005. We compared children whose mothers had CUD to those whose mothers did not, and assessed the risk of DBDs in these children. Both CUD and DBDs were...