Psychoactive substances are natural or synthetic substances that act on the central nervous system and alter mental processes such as mood, perception, cognition, consciousness, and behaviour. These substances may be legally prescribed medications (e.g., pain medications or sedatives), legally available substances such as alcohol or caffeine, or controlled or illicit drugs. Psychoactive substances can be used for medical, social, cultural, or recreational purposes, but some carry risks of misuse, dependence, and health or social harms when used in harmful ways.
Psychoactive Substances
Suboxone, Kratom, and 7-Hydroxymitragynine (7-OH): A Guide to Withdrawal Risks, Buprenorphine Treatment, and Clinical Considerations
Kratom, 7-OH, and Suboxone: Withdrawal, Blocking Effects, and Treatment Options Quick answer: Yes, Suboxone can block the effects of kratom because buprenorphine binds strongly to the brain’s opioid receptors. However, taking Suboxone too...
The force of the local community to reduce drug-related problems
On the way to the Barcelona Forum on Drugs, the 8th Thematic Discussion aims to pay tribute to local communities around the world in addressing drug-related problems. A selection of best practices from Barcelona will be presented, the city hosting the forum.
Drug production and precursors — EUDA ongoing activities
The European Union Drugs Agency (EUDA) continues to monitor illicit drug production and precursor chemicals across Europe to improve understanding of how drug markets are evolving. Production within the European Union is primarily focused...
European Drug Report 2026: Trends and Developments
The European Drug Report 2026: Trends and Developments provides the latest overview of the drug situation across Europe, drawing on data from EU Member States, Türkiye, and Norway. The report examines patterns of drug use, drug-related...
The Tobacco Control Scale 2025 in Europe
The Tobacco Control Scale 2025 shows that progress in tobacco control across Europe has slowed, with more countries recording lower scores than in previous years. Key reasons include the failure to regulate heated tobacco products in the same way as cigarettes and the lack of adjustments to tobacco taxes and prices to keep pace with inflation.
A European Guide on Dual disorders: Health and Social Responses
This European guide by EUDA highlights the importance of addressing dual disorders, where mental health conditions and substance use disorders occur at the same time. These co-occurring conditions are common and often lead to poorer health...
The Dope Test
Understanding Drug Testing What Is a Drug Test? A drug test is the scientific analysis of biological samples to determine whether narcotic drugs, psychoactive substances, or their metabolites are present in the body. Samples may include...
Say "NO" to Drugs
Understanding Psychoactive Substances and Substance Use What Are Psychoactive Substances? Psychoactive substances are substances that affect the way the brain and body function, influencing thoughts, emotions, perceptions, and behaviour...
Ice in Khyber Pakhtunkhwa: Understanding Methamphetamine Use and Community Responses
ISSUP in Pakistan presents 'Ice in Khyber Pakhtunkhwa: Understanding Methamphetamine Use and Community Responses', a webinar with Dr. Sameer Ul Khaliq Jan.
Ice in Khyber Pakhtunkhwa: Understanding Methamphetamine Use and Community Responses
ISSUP in Pakistan presents 'Ice in Khyber Pakhtunkhwa: Understanding Methamphetamine Use
and Community Responses', a webinar with Dr. Sameer Ul Khaliq Jan.