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Abstract

Even moderate doses of alcohol cause considerable impairment of motor coordination, an effect that substantially involves potentiation of GABAergic activity at δ subunit-containing GABAAreceptors (δ-GABAARs). Here, we demonstrate...

Abstract

Purpose

To review studies about the reliability and validity of self-reported alcohol consumption measures among adults, an area which needs updating to reflect current research.

Methods

Databases (PUBMED (1966-present)...

ABSTRACT

Objectives: This study focused on lapse shortly after an attempt to quit smoking. Ecological momentary assessment (EMA) studies have mapped real-time situational factors that induce lapses in everyday life. However, the possible...

Abstract

Objectives: Our study aimed to evaluate the effectiveness of general practitioners’ (GPs’) smoking cessation support (SCS).

Study design: We carried out a cross-sectional study between February and April 2016.

Setting and...

Abstract

Background: While the prevalence of tobacco smoking in the general population has declined, it remains exceptionally high for smokers with severe mental illness (SMI), despite significant public health measures. This project aims...

Abstract

Introduction: The aim of the study is to analyse the prevalence of smoking among resident physicians at a regional university hospital. In addition, we examined the trends in the smoking behaviour of physicians in relation to...

ABSTRACT

The proportion of drug abuse users that develop dependence does not represent the totality of users. Therefore, there is a substantial proportion of users that do not develop a substance use disorder (SUD). For example, in Mexico...

Summary

Background

Some parents supply alcohol to their children, reportedly to reduce harm, yet longitudinal research on risks associated with such supply is compromised by short periods of observation and potential confounding. We aimed...

Abstract

This article examines the association between drug use severity and mortality in primary care patients with substance use disorders. In 848 individuals with known vital status, severity was low in 32%, intermediate in 38%, or...

Cigarette smoking damages just about every organ in the body and reduces overall health. Even with the prevalence of accessible nicotine replacement therapies and behavioral counseling, there remains a need for alternative therapies to...

Adenosine receptors (AR) are a family of G-protein coupled receptors, comprised of four members, named A1, A2A, A2B, and A3 receptors, found widely distributed in almost all human body tissues and organs. To date, they are known to...

Transcranial direct current stimulation (tDCS) applied over the dorsolateral prefrontal cortex (DLPFC) has been shown to reduce cravings in tobacco addiction; however, results have been somewhat mixed. In this study, we hypothesized that...

Aim: The present study aimed to study the associations between substance use patterns and types of crimes in prisoners with substance use problems, and specifically whether substance use patterns were different in violent offenders.

Metho...

ABSTRACT

Prevention science has identified evidence-based strategies for reducing alcohol and other drug use among adolescents, such as Brief Interventions (BI) and Motivational Interviewing (MI). However, there is little evidence about...

Abstract

Study Objectives

There remains an important and unmet need for fully effective and acceptable treatments in obstructive sleep apnea (OSA). At present, there are no approved drug treatments. Dronabinol has shown promise for OSA...

Abstract

Background

Harmful alcohol consumption in older people has increased and effective approaches to understanding and addressing this societal concern are needed.

Methods

Systematic review of qualitative studies in older...

Abstract

Objective: To determine the feasibility of a Community-Based Participatory Tobacco Dependence Strategy (PROMPT) in the inner city population of Ottawa (Canada).

Design: A feasibility mixed methods prospective cohort study...