Applying interventions designed to reduce and manage the symptoms of substance use disorders.
Treatment
Effects of Naltrexone on Alcohol Self-Administration and Craving
Abstract Randomized clinical trials have established the efficacy of naltrexone for reducing quantity of alcohol consumption and incidence of relapse to heavy drinking. To evaluate putative treatment mechanisms, human laboratory studies...
Effectiveness Bank Drug Treatment Matrix: Creating a Lifesaving Treatment and Harm Reduction System
Online course moves on to the whole-system level, where treatment and harm reduction services working in synergy are the best hope for reversing the hepatitis C epidemic - but can any feasible local or national system succeed in this...
Engagement within a Mobile Phone-Based Smoking Cessation Intervention for Adolescents
ABSTRACT Background: Although mobile phone-delivered smoking cessation programs are a promising way to promote smoking cessation among adolescents, little is known about how adolescents might actually use them. Objective: The aim of this...
Novel Vaccines against Morphine Heroin
SUMMARY Drug addiction is one of the most important health problems worldwide. This pathology results in the death of about 500,000 individuals annually around the globe. Despite this scenario, the development of effective drug therapies...
The Opioid Epidemic: From Evidence to Impact
EXECUTIVE SUMMARY While prescription opioids serve an invaluable role for the treatment of cancer pain and pain at the end of life, their overuse for acute and chronic non-cancer pain as well as the increasing availability of heroin and...
Determining Counselling Communication Strategies Associated with Successful Quits in the 'Stop Smoking Programme' in East London
Abstract Objectives: To determine communication strategies associated with smoking cessation in the National Health Service community pharmacy Stop Smoking programme. Setting: 11 community pharmacies in three inner east London boroughs...
Cognitive Complexity of Clients and Counsellors during Motivation-Based Treatment for Smoking Cessation
Abstract Objective: Motivational interviewing (MI) is a widely used and promising treatment approach for aiding in smoking cessation. The present observational study adds to other recent research on why and when MI works by investigating a...
Efficacy and Safety of Cannabinoid Oromucosal Spray for Multiple Sclerosis Spasticity
Abstract Background: The approval of 9-δ-tetrahydocannabinol and cannabidiol (THC:CBD) oromucosal spray (Sativex) for the management of treatment-resistant multiple sclerosis (MS) spasticity opened a new opportunity for many patients. The...
The Effectiveness of Injectable Extended-Release Naltrexone vs Daily Buprenorphine-Naloxone for Opioid Dependence
Key Points Question: Are monthly intramuscular injections with extended-release naltrexone hydrochloride as effective as daily oral buprenorphine–naloxone hydrochloride in reducing the use of heroin and other illicit substances in newly...
Unmet Treatment Needs for People with Mental Health and Substance Use Disorders
In the US, less than 10% of adults with co-occurring mental health problems and substance use disorders get treatment for both. 50% do not receive treatment for either. This highlights the vast discrepancy between the prevalence of co...