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Binge drinking episode causes acute, specific alterations in systemic and hepatic inflammation-related markers
Abstract
Background
Frequent binge drinking is a known contributor to alcohol-related harm, but its impact on systemic and hepatic inflammation is not fully understood. We hypothesize that changes in immune markers play a central role...
Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders
Abstract
The substantial individual heterogeneity that characterizes people with mental illness is often ignored by classical case–control research, which relies on group mean comparisons. Here we present a comprehensive, multiscale...
Association between vmPFC gray matter volume and smoking initiation in adolescents
Abstract
Smoking of cigarettes among young adolescents is a pressing public health issue. However, the neural mechanisms underlying smoking initiation and sustenance during adolescence, especially the potential causal interactions...
Alcohol-associated bowel disease: new insights into pathogenesis
Abstract
Excessive alcohol drinking can cause pathological changes including carcinogenesis in the digestive tract from mouth to large intestine, but the underlying mechanisms are not fully understood. In this review, we discuss the...
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Learnings from a prison-based drug treatment program on planning for release
Substance use disorder is common among people in prison worldwide.
This report explores the experiences of males in prison who completed and those who did not complete a group-based drug and alcohol program, to gain insight into their...
Supporting displaced people from Afghanistan and host communities in neighbouring countries – UNODC regional workshop on drug use prevention, treatment and care
From 5th to 9th June, UNODC organized a hybrid regional workshop with a total of 42 participants from the government, civil society organizations (CSOs) and UN agencies, to assist the strengthening of evidence-based prevention, treatment...
Stop Overdose Safely: UNODC successfully trained Ukrainian CSOs on emergency management of opioid overdose
From 6th to 8th June 2023, the UNODC Programme Office for Ukraine (POUKR) and the UNODC Prevention, Treatment and Rehabilitation Section (PTRS), jointly with Ukrainian NGOs, “Club Eney” and “Conviktus”, organized an in-person “Stop Overdose...
Trends in Alcohol-Related Deaths by Sex in the US, 1999-2020
Abstract
Importance Alcohol consumption rates have been increasing among women in the US, which may affect mortality rates and sex gaps. Therefore, conducting a comprehensive assessment of sex differences in alcohol-related deaths is...
Integrating Opioid Use Disorder Treatment Into Primary Care Settings
Abstract
Importance Medication for opioid use disorder (MOUD) (eg, buprenorphine and naltrexone) can be offered in primary care, but barriers to implementation exist.
Objective To evaluate an implementation intervention over 2 years...
Self-reported Xylazine Experiences: A Mixed-methods Study of Reddit Subscribers
Abstract
Objectives
Xylazine is an α2-agonist increasingly prevalent in the illicit drug supply. Our objectives were to curate information about xylazine through social media from people who use drugs (PWUDs). Specifically, we sought...
CIJ Informa No. 100
CIJ Informa No.100
Centros de Integración Juvenil (CIJ), host institution of the ISSUP Mexico Chapter, has published the 100th edition of the CIJ Informa Magazine, where in addition to sharing information about the different activities...
Use of Medication for Opioid Use Disorder Among Adults With Past-Year Opioid Use Disorder in the US, 2021
Discussion
Despite guidelines recommending MOUD, approximately 1 in 5 adults with past-year OUD received any MOUD. Furthermore, some groups were substantially less likely to receive MOUD, in particular Black adults, women, those...
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ISSUP is delighted to be revealing our new layout for the Knowledge Share, and hope that it improves your experience.
The Knowledge Share continues to bring you the latest news, research, practice, resources and publications from the...
State Stakeholders Consultation on child protection
The State Stakeholders Consultation on Child Protection with the theme "Children in Conflict with Law: Prevention, Restorative Justice, Diversion, and Alternatives to Detention" was organized by the Juvenile Justice Committee, High Court of
...New rule in New Zealand requires warning on all packaged alcohol
A new rule will require all packaged alcohol being sold to have warnings on the label about the harm it can cause to unborn babies.
The food safety agency says the move is supported by advice from doctors, midwives, the Ministry of...
Stigmatising imagery for substance use disorders
Stigma is a barrier to treatment for individuals with substance use issues. Although there has been research conducted exploring the impact of stigmatising language, less is known about the effects of stigmatising images.
This...
UNODC conducted Regional Training of Trainers on UTC 20 in Central Asia
The UNODC Regional Office for Central Asia in collaboration with Prevention, Treatment and Rehabilitation Section, UNODC HQ held a Regional Training of Trainers (ToT) on Course 20 – “Populations with Special Clinical Needs” which took place...
Ecolink concludes short courses on Science of addiction among youths
Ecolink Institute has concluded two batches on the science of addiction among youths, mostly from Universities, with the intention to provide them an introduction to psychoactive substances and how it affects their brain and cause addiction...
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