overdose

Improving Outcomes in the Treatment of Opioid Dependence (IOTOD) Conference

Online,

The 21st IOTOD live virtual conference is back for 2023, with an exciting 2-day educational agenda including interactive seminars, thought-provoking talks, satellite symposia, and expert-led panel discussions.

Who should attend?

Ideal for primary and secondary care clinicians looking to improve their confidence in managing opioid dependence, as well as those with an interest in the field.

Use of Digital Technology in Overdose Prevention: Drugs Research Network Scotland Knowledge Exchange

Online,

Drug overdoses continue to impact different countries in the world particularly in North America and Scotland. Scotland has the most severe Drug-Related Deaths (DRD) problem in Europe, almost four times that of other countries. Innovative solutions are required to support people at risk of harm. Digital technology such as smartphone application, wearable or sensors, could help to identify and prevent overdose.

Moving towards a continuum of safer supply options for people who use drugs: A qualitative study exploring national perspectives on safer supply among professional stakeholders in Canada

Foreman-Mackey, A., Pauly, B., Ivsins, A. et al. Moving towards a continuum of safer supply options for people who use drugs: A qualitative study exploring national perspectives on safer supply among professional stakeholders in Canada. Subst Abuse Treat Prev Policy 17, 66 (2022).
Publication Date

Background

Novel public health interventions are needed to address the toxic drug supply and meet the needs of people who use drugs amidst the overdose crisis.

Association of Methamphetamine and Opioid Use With Nonfatal Overdose in Rural Communities

Korthuis PT, Cook RR, Foot CA, et al. Association of Methamphetamine and Opioid Use With Nonfatal Overdose in Rural Communities. JAMA Netw Open. 2022;5(8):e2226544. doi:10.1001/jamanetworkopen.2022.26544
Publication Date

Abstract

Importance  Overdoses continue to increase in the US, but the contribution of methamphetamine use is understudied in rural communities.

Objective  To estimate the prevalence of methamphetamine use and its correlates among people who use drugs (PWUD) in rural US communities and to determine whether methamphetamine use is associated with increased nonfatal overdoses.

Development and Validation of Machine Models Using Natural Language Processing to Classify Substances Involved in Overdose Deaths

Goodman-Meza D, Shover CL, Medina JA, Tang AB, Shoptaw S, Bui AAT. Development and Validation of Machine Models Using Natural Language Processing to Classify Substances Involved in Overdose Deaths. JAMA Netw Open. 2022;5(8):e2225593. doi:10.1001/jamanetworkopen.2022.25593
Publication Date
Abstract

Importance  Overdose is one of the leading causes of death in the US; however, surveillance data lag considerably from medical examiner determination of the death to reporting in national surveillance reports.

Objective  To automate the classification of deaths related to substances in medical examiner data using natural language processing (NLP) and machine learning (ML).

Effect of a Peer-Led Behavioral Intervention for Emergency Department Patients at High Risk of Fatal Opioid Overdose A Randomized Clinical Trial

Beaudoin FL, Jacka BP, Li Y, et al. Effect of a Peer-Led Behavioral Intervention for Emergency Department Patients at High Risk of Fatal Opioid Overdose: A Randomized Clinical Trial. JAMA Netw Open. 2022;5(8):e2225582. doi:10.1001/jamanetworkopen.2022.25582
Publication Date
Abstract

Importance  Fatal and nonfatal opioid overdoses are at record levels, and emergency department (ED) visits may be an opportune time to intervene. Peer-led models of care are increasingly common; however, little is known about their effectiveness.

Variations in national availability of waivered buprenorphine prescribers by racial and ethnic composition of zip codes

Hirchak, K.A., Amiri, S., Kordas, G. et al. Variations in national availability of waivered buprenorphine prescribers by racial and ethnic composition of zip codes. Subst Abuse Treat Prev Policy 17, 41 (2022). https://doi.org/10.1186/s13011-022-00457-3
Publication Date

Background

Opioid overdose remains a public health crisis in diverse communities. Between 2019 and 2020, there was an almost 40% increase in drug fatalities primarily due to opioid analogues of both stimulants and opioids. Medications for opioid use disorder (MOUD; e.g., buprenorphine) are effective, evidence-based treatments that can be delivered in office-based primary care settings.

Let’s Talk Overdose 2022

Online,

2-DAY CONFERENCE

April 6, 2022
Early risk – Early intervention: Overdose among Youth

Changing drug markets and the COVID-19 pandemic have created an increasingly serious need to develop specific solutions for young people at risk of overdose. Everyone is welcome to join the conversations about early intervention, prevention and youth-focused treatments for high-risk substance use.

An observational prospective cohort study of naloxone use at witnessed overdoses, Kazakhstan, Kyrgyzstan, Tajikistan, Ukraine

Dietze, P., Gerra, G., Poznyak, V., Campello, G., Kashino, W., Dzhonbekov, D., Kiriazova, T., Nikitin, D., Terlikbayeva, A., Krupchanka, D., & Busse, A. (2022). An observational prospective cohort study of naloxone use at witnessed overdoses, Kazakhstan, Kyrgyzstan, Tajikistan, Ukraine [Étude de cohorte prospective observationnelle sur l'usage de naloxone en cas d'overdose au Kazakhstan, au Kirghizistan, au Tadjikistan et en Ukraine]. Bulletin of the World Health Organization, 100(3), 187–195. https://doi.org/10.2471/BLT.21.286459
Publication Date

Abstract

Objective

To determine whether participation in the United Nations Office on Drugs and Crime (UNODC) and the World Health Organization’s (WHO) Stop Overdose Safely (S-O-S) take-home naloxone training project in Kazakhstan, Kyrgyzstan, Tajikistan and Ukraine resulted in naloxone use at witnessed opioid overdoses.

Risk of Opioid Overdose Associated With Concomitant Use of Oxycodone and Selective Serotonin Reuptake Inhibitors

Yunusa I, Gagne JJ, Yoshida K, Bykov K. Risk of Opioid Overdose Associated With Concomitant Use of Oxycodone and Selective Serotonin Reuptake Inhibitors. JAMA Netw Open. 2022;5(2):e220194. doi:10.1001/jamanetworkopen.2022.0194
Publication Date
Abstract

Importance  Some selective serotonin reuptake inhibitors (SSRIs) inhibit the enzymes responsible for the metabolism of oxycodone, a potent prescription opioid. The clinical consequences of this interaction on the risk of opioid overdose have not been elucidated.