overdose

Association of Methamphetamine and Opioid Use With Nonfatal Overdose in Rural Communities

Citation
Korthuis PT, Cook RR, Foot CA, et al. Association of Methamphetamine and Opioid Use With Nonfatal Overdose in Rural Communities. JAMA Netw Open. 2022;5(8):e2226544. doi:10.1001/jamanetworkopen.2022.26544
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Abstract

Importance  Overdoses continue to increase in the US, but the contribution of methamphetamine use is understudied in rural communities.

Objective  To estimate the prevalence of methamphetamine use and its correlates among people who use drugs (PWUD) in rural US communities and to determine whether methamphetamine use is associated with increased nonfatal overdoses.

Development and Validation of Machine Models Using Natural Language Processing to Classify Substances Involved in Overdose Deaths

Citation
Goodman-Meza D, Shover CL, Medina JA, Tang AB, Shoptaw S, Bui AAT. Development and Validation of Machine Models Using Natural Language Processing to Classify Substances Involved in Overdose Deaths. JAMA Netw Open. 2022;5(8):e2225593. doi:10.1001/jamanetworkopen.2022.25593
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Abstract

Importance  Overdose is one of the leading causes of death in the US; however, surveillance data lag considerably from medical examiner determination of the death to reporting in national surveillance reports.

Objective  To automate the classification of deaths related to substances in medical examiner data using natural language processing (NLP) and machine learning (ML).

Effect of a Peer-Led Behavioral Intervention for Emergency Department Patients at High Risk of Fatal Opioid Overdose A Randomized Clinical Trial

Citation
Beaudoin FL, Jacka BP, Li Y, et al. Effect of a Peer-Led Behavioral Intervention for Emergency Department Patients at High Risk of Fatal Opioid Overdose: A Randomized Clinical Trial. JAMA Netw Open. 2022;5(8):e2225582. doi:10.1001/jamanetworkopen.2022.25582
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Abstract

Importance  Fatal and nonfatal opioid overdoses are at record levels, and emergency department (ED) visits may be an opportune time to intervene. Peer-led models of care are increasingly common; however, little is known about their effectiveness.

Variations in national availability of waivered buprenorphine prescribers by racial and ethnic composition of zip codes

Citation
Hirchak, K.A., Amiri, S., Kordas, G. et al. Variations in national availability of waivered buprenorphine prescribers by racial and ethnic composition of zip codes. Subst Abuse Treat Prev Policy 17, 41 (2022). https://doi.org/10.1186/s13011-022-00457-3
Publication Date

Background

Opioid overdose remains a public health crisis in diverse communities. Between 2019 and 2020, there was an almost 40% increase in drug fatalities primarily due to opioid analogues of both stimulants and opioids. Medications for opioid use disorder (MOUD; e.g., buprenorphine) are effective, evidence-based treatments that can be delivered in office-based primary care settings.

Let’s Talk Overdose 2022

Online,

2-DAY CONFERENCE

April 6, 2022
Early risk – Early intervention: Overdose among Youth

Changing drug markets and the COVID-19 pandemic have created an increasingly serious need to develop specific solutions for young people at risk of overdose. Everyone is welcome to join the conversations about early intervention, prevention and youth-focused treatments for high-risk substance use.

An observational prospective cohort study of naloxone use at witnessed overdoses, Kazakhstan, Kyrgyzstan, Tajikistan, Ukraine

Citation
Dietze, P., Gerra, G., Poznyak, V., Campello, G., Kashino, W., Dzhonbekov, D., Kiriazova, T., Nikitin, D., Terlikbayeva, A., Krupchanka, D., & Busse, A. (2022). An observational prospective cohort study of naloxone use at witnessed overdoses, Kazakhstan, Kyrgyzstan, Tajikistan, Ukraine [Étude de cohorte prospective observationnelle sur l'usage de naloxone en cas d'overdose au Kazakhstan, au Kirghizistan, au Tadjikistan et en Ukraine]. Bulletin of the World Health Organization, 100(3), 187–195. https://doi.org/10.2471/BLT.21.286459
Publication Date

Abstract

Objective

To determine whether participation in the United Nations Office on Drugs and Crime (UNODC) and the World Health Organization’s (WHO) Stop Overdose Safely (S-O-S) take-home naloxone training project in Kazakhstan, Kyrgyzstan, Tajikistan and Ukraine resulted in naloxone use at witnessed opioid overdoses.

Risk of Opioid Overdose Associated With Concomitant Use of Oxycodone and Selective Serotonin Reuptake Inhibitors

Citation
Yunusa I, Gagne JJ, Yoshida K, Bykov K. Risk of Opioid Overdose Associated With Concomitant Use of Oxycodone and Selective Serotonin Reuptake Inhibitors. JAMA Netw Open. 2022;5(2):e220194. doi:10.1001/jamanetworkopen.2022.0194
Publication Date
Abstract

Importance  Some selective serotonin reuptake inhibitors (SSRIs) inhibit the enzymes responsible for the metabolism of oxycodone, a potent prescription opioid. The clinical consequences of this interaction on the risk of opioid overdose have not been elucidated.

Staff preferences towards electronic data collection from a national take-home naloxone program: a cross-sectional study

Citation
Ericson, Ø.B., Eide, D., Lobmaier, P. et al. Staff preferences towards electronic data collection from a national take-home naloxone program: a cross-sectional study. Subst Abuse Treat Prev Policy 17, 13 (2022). https://doi.org/10.1186/s13011-022-00440-y
Publication Date

In Norway, overdose mortality is over 260 per year, with opioids being implicated in the majority of cases. In 2014, the Norwegian government announced a government-funded nationwide overdose prevention initiative in response to the country's high overdose rates. A broad take-home naloxone (THN) program was one of the key treatments featured.

Evidence-Based Strategies for Preventing Opioid Overdose

Washington DC, United States,

Join the Addiction Policy Forum on March 7th from 1-2:30 p.m. (ET) for a webinar and Q&A to discuss key strategies to preventing opioid overdose with experts from the Centers for Disease Control and Prevention (CDC).