Epidemiology and Etiology
During the past decade, heated aerosolized nicotine delivery systems (HANDS) —mainly e-cigarettes—have surpassed nicotine replacement therapy as the most utilized aids for stopping smoking in England.
Each year there are 3 million deaths as a result of the harmful use of alcohol.
As alcohol gets broken down, chemicals affect the way our body sends signals and communicates and increase the chances of developing cancer.
In this article, published in Lancet Oncology, the researchers present global, regional, and national estimates of alcohol-attributable cancer burden in 2020.
During the COVID-19 pandemic, countries around the world have introduced lockdown restrictions and social distancing measures to reduce the spread of the virus. Researchers are keen to understand how these policies and new measures have influenced drinking behaviours within particular groups.
Previous research using whole-brain neuroimaging techniques has revealed structural differences of grey matter (GM) in alcohol use disorder (AUD) patients. However, some of the findings diverge from other neuroimaging studies and require further replication.
Intimate-Partner Violence and its Relationship With Substance Consumption by Mexican Men and Women: National Survey on Addictions
Introduction: Research findings about intimate-partner violence (IPV) have focused mostly on women as victims of violence. Recent studies show the importance of violence inflicted by women towards men or between same-sex couples.
Association of genetic liability to smoking initiation with e-cigarette use in young adults: A cohort study
Tobacco smoking and e-cigarette use are strongly associated, but it is currently unclear whether this association is causal, or due to shared factors that influence both behaviours such as a shared genetic liability. The aim of this study was to investigate whether polygenic risk scores (PRS) for smoking initiation are associated with ever use of e-cigarettes.
Disentangling substance use and related problems: urgency predicts substance-related problems beyond the degree of use
Substance use disorders are reliably associated with high impulsivity and sensation seeking. Importantly, both precede problematic substance use, implicating them as risk factors. Individuals with substance use disorders show variable degrees of substance use (combined quantity and frequency) and substance-related problems and differ in both aspects from healthy controls.
A randomised, double-blind study investigating the relationship between early childhood trauma and the rewarding effects of morphine
Experiences of childhood trauma (abuse and neglect) are disproportionately higher in those with opioid use disorder (OUD).
Childhood trauma may affect the reinforcing and rewarding properties of opioid drugs and responses to pain, potentially via developmental changes to the endogenous opioid system. This has been supported by preclinical research, yet this has not been investigated in non-addicted humans.
The World Drug Report 2021 provides an analysis of the latest supply and demand of cannabis, opioids, cocaine and amphetamine-type stimulants.