Psychoactive substances are natural or synthetic substances that act on the central nervous system and alter mental processes such as mood, perception, cognition, consciousness, and behaviour. These substances may be legally prescribed medications (e.g., pain medications or sedatives), legally available substances such as alcohol or caffeine, or controlled or illicit drugs. Psychoactive substances can be used for medical, social, cultural, or recreational purposes, but some carry risks of misuse, dependence, and health or social harms when used in harmful ways.
Psychoactive Substances
National Academy of Medicine Releases New Special Publication Guide
September 21, 2017 Halting the opioid epidemic requires aggressive action across multiple dimensions, including informed, active, and determined front-line leadership from health clinicians working in every setting throughout the nation...
Transcranial Magnetic Stimulation of Dorsolateral Prefrontal Cortex Reduces Cocaine Use
Abstract Recent animal studies demonstrate that compulsive cocaine seeking strongly reduces prelimbic frontal cortex activity, while optogenetic stimulation of this brain area significantly inhibits compulsive cocaine seeking, providing a...
Chemsex: An Emergent Phenomenon
Chemsex is the term given to the intentional use of psychoactive drugs in order to maintain sexual relations between men who have sex with men (MSM), usually for long periods of time and with multiple partners. This phenomenon has also been...
Lack of Sleep and Substance Use: A Worrying Link
Children and adolescents need more sleep than adults. A good night's sleep for those in their teens is considered to be 8.5 – 9.5 hours. Just over ¼ of US high school students get 8+ hours of sleep a night, according to the 2015 Youth Risk...
What is 'Substance Use'?
The following tries to summarise both what “substance use” is, and some of the issues that surround the term.
Synthetic Cathinone and Cannabinoid Designer Drugs Pose a Major Risk for Public Health
As part of an increasing worldwide use of designer drugs, recent use of compounds containing cathinones and synthetic cannabinoids is especially prevalent. Here, we reviewed current literature on the prevalence, epidemiology, bio-behavioral...
Energy Drinks, Drug Use and the Developing Brain
New research funded by the National Institute on Drug Abuse (NIDA) has found that university students who regularly consume energy drinks are more likely to develop alcohol use disorders later in life. The same students are also at greater...
Why Are Females More Sensitive to the Effects of Cocaine?
Previous research has shown that females report more intense highs from cocaine use than do males, and that the former are more likely to become addicted to the drug, given the presence of the female hormone estradiol. However, little is...
Environmental Stressors, Socioeconomic Factors, and Alcohol-Related Problems among Argentinian College Students
Abstract: Introduction: The relationship between alcohol consumption, individual characteristics, and alcohol-related problems may vary according to environmental characteristics in certain populations. Objective: To explore the existence...
A Serious Matter: Laughing Gas Prompts Review of UK’s Psychoactive Substances Act
Introduced in 2016, The Psychoactive Substances Act is designed to deal with the influx of new drugs often labelled ‘legal highs’. The Act bans any substance that "by stimulating or depressing the person’s central nervous system… affects...