Psychoactive substances are natural or synthetic substances that act on the central nervous system and alter mental processes such as mood, perception, cognition, consciousness, and behaviour. These substances may be legally prescribed medications (e.g., pain medications or sedatives), legally available substances such as alcohol or caffeine, or controlled or illicit drugs. Psychoactive substances can be used for medical, social, cultural, or recreational purposes, but some carry risks of misuse, dependence, and health or social harms when used in harmful ways.
Psychoactive Substances
Factors associated with cocaine use in users of injectable heroin in Colombia
OVERVIEW Introduction: People who consume heroin and cocaine have increased sexual activity, risk behaviours associated with injection and inconsistent condom use, which would increase the risk of sexually transmitted infections and the...
Drug Addiction: Is Brain Stimulation the Answer?
Transcranial magnetic brain stimulation has allowed researchers to reduce how "excited" the brains of chronic cocaine and alcohol users become in response to drug cues. Drug addiction is a chronic disease affecting 5.4 percent of the...
A Double Blind, Placebo Controlled Trial of Modafinil for the Treatment of Cocaine Dependence without Co-Morbid Alcohol Dependence
Like methadone for heroin dependence, modafinil is an oral medication with similar effects to cocaine but milder, slower in onset and longer-acting - properties which might help plug the gap in effective pharmacotherapies for dependence on...
Medical Marijuana Users Are More Likely to Use Prescription Drugs Medically and Nonmedically
ABSTRACT Objectives: Previous studies have found a negative population-level correlation between medical marijuana availability in US states, and trends in medical and nonmedical prescription drug use. These studies have been interpreted as...
Candyflipping and Other Combinations: Identifying Drug–Drug Combinations from an Online Forum
Novel psychoactive substances (NPS) refer to synthetic compounds or derivatives of more widely known substances of abuse that have emerged over the last two decades. Case reports suggest that users combine substances to achieve desired...
Taking a New Line on Drugs
This report, ‘Taking a New Line on Drugs’, comes at a timely moment for drugs strategy both in the UK and across the world. The special session of the United Nations General Assembly on the world drug problem, which took place in New York...
The health and social effects of the medicinal use of cannabis
Resumen Cannabis is the psychoactive substance under international control used in the world. In 2013, about 181.8 million of people from 15 to 64 years worldwide have used cannabis without medical purpose (estimate of uncertainty of 128.5...
Social and effects to the health of non-medical cannabis use
Overview Cannabis is the substance psychoactive under international control most widely used around the world. It is estimated that, in 2013, 181.8 million people aged 15 to 64 consumed cannabis without medical purposes around the world...
Study on patterns of psychoactive substances consumption in indigenous and groups originating from the city of Mexico 2014
This interesting text is the product of collaboration between the Institute of care and prevention of addictions (IAPA) and the National Institute of Psychiatry Ramón de la Fuente Muñiz (INFRDM), institutions that share the commitment to...
2017 annual bulletin, National Observatory on drugs of Guatemala
INTRODUCTION The National Observatory on drugs (OND) of the SECCATID works in the Constitution of a network of information on drugs (RID) in Guatemala, with the members of the Commission against addiction and illicit drugs - CCATID - and...