Background

Stigma related to drug use is a well-documented barrier to engaging and remaining on medication for opioid use disorder (MOUD), yet little is known about how stigma operates across multiple social and institutional settings in low-resource contexts.

Methods

This qualitative study draws on 40 in-depth interviews with current and former MOUD clients and four focus groups with 35 current clients at an opioid treatment clinic in Dar es Salaam, Tanzania. Transcripts were thematically analyzed to explore how stigma influenced MOUD adherence and retention.

Results

Five themes emerged...

Background

Smoking is more common in lower socioeconomic position (SEP) groups, but smoking cessation interventions are less effective for these groups. StopCoach, an mHealth intervention, supports people with lower SEP in quitting smoking. A non-randomized controlled trial found that adding StopCoach to accredited smoking cessation counselling (SCC) led to higher abstinence rates immediately after and one year after SCC, compared to SCC alone. Users also rated its usability, acceptability, and practicality positively. Recent studies show a dose-response relationship, where more mHealth use...

With the increased role of nurses in caring for patients with substance addiction, there was a clear need to develop the Addiction Nursing Competencies to guide and support the nursing workforce. A literature search revealed a lack of formal instruments to assess and guide nurses in caring for persons with substance use disorders. The Addiction Nursing Competencies were created using existing nursing education frameworks and addiction nurse care manager clinical guidelines.

CSUCH’s data visualisation tool can be used to estimate substance use trends across the country. The data helps inform programs, practices, and research to protect communities, save lives, and improve the well-being of people in Canada.

Spotlight: Top 3 causes of death due to substance use in Canada 

More than 200 people died each day due to substance use (SU) in 2020 (the latest year for which data are available). That works out to 73,994 deaths that year. The average age of death due to SU was 45 years. Tobacco use caused 63% (46,366) of SU-related deaths, followed by alcohol at 23%...

Background
Binge drinking, defined as consuming five or more alcoholic drinks in a single session, is a major public health issue. It leads to cognitive and motor impairments and is linked to numerous health problems. This study aims to analyze globally published peer-reviewed literature on binge drinking.

Methods
A thorough search was conducted in the Scopus database using keywords related to binge drinking. Specific criteria were applied to filter the results, resulting in 2,763 relevant research papers. VOSviewer software was used to analyze and visualize connections between these studies...

Background
Cognitive deficits are common in patients with substance use disorder (SUD) and can impact treatment outcomes. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is a widely used tool that could help identify cognitive impairments in SUD patients. This systematic review examines the RBANS’ effectiveness in detecting cognitive impairment in SUD patients and discusses knowledge gaps and the need for further research.

Methods
A systematic search was conducted in PsycINFO, Medline, and Cochrane databases to find relevant studies on the use of RBANS in SUD...

Background
A non-medicalized safer supply model called a “Compassion Club” has recently been evaluated. The model involved providing rigorously tested and accurately labeled illicit substances to members at cost. Operating for 14 months in Vancouver's Downtown Eastside, the initiative aimed to explore the effects and feasibility of this approach among individuals at risk of fatal overdose.

Methods
At the one-year mark, 43 club members completed a survey for this cross-sectional analysis. Descriptive statistics were used to assess the perceived impact of membership on factors like drug use...

Addiction and obesity share similar neurological pathways, both linked to compulsive behaviors and the brain's reward system. Research has highlighted the potential of GLP-1 receptor agonists, originally developed for diabetes, to help manage both appetite and addictive cravings. These medications, such as semaglutide, may regulate addictive behaviors by influencing reward circuits in the brain. However, they come with potential side effects, and their long-term effects are still under investigation.

In addition, a new compound, 5-Methoxy-2-aminoindane (MEAI), is being researched for its...

Researchers at Virginia Commonwealth University (VCU) have developed a new version of a medication for opioid use disorder that could offer longer-lasting treatment. Current medications for opioid addiction often require daily doses, but the new formulation of nor-levo-alpha-acetylmethadol (nor-LAAM) is designed to be taken once a month or less frequently. This long-acting medication has shown promise in reducing opioid use and withdrawal symptoms in rodent models. The goal is to provide an alternative to existing treatments like methadone and buprenorphine, which come with barriers such as...

Few studies have looked into how cannabis use during pregnancy affects the development of disruptive behavioral disorders (DBDs) in children, often using small sample sizes and self-reported data. This study aimed to understand the link between maternal cannabis use disorder (CUD) during pregnancy and after childbirth, and the risk of DBDs in children. We used health data from New South Wales, Australia, for children born between 2003 and 2005. We compared children whose mothers had CUD to those whose mothers did not, and assessed the risk of DBDs in these children. Both CUD and DBDs were...