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Treatment Research

Treatment Research
DiscussionsFilesImagesVideosLinksEventsKnowledge ShareAll
James Harvey

Managing Drug Use Disorder Treatment Services in Line with International ‘Key Quality Standards’: A Handbook for Managers

Shared by James Harvey (ISSUP staff) - 21 May 2025
Managing drug use disorder treatment services in line with international ‘Key Quality Standards’.
Format
Guide
Published by / Citation
International Consortium on Quality (ICQ)
This resource is designed to help leaders and managers transfer current technology on ‘what works’ and what is efficient and ethical management in drug treatment into practice.
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Rasha Abi Hana

Addiction Nursing Competencies A Comprehensive Toolkit for the Addictions Nurse

Shared by Rasha Abi Hana - 15 May 2025
Format
Scientific article
Published by / Citation
Wason, Kristin MSN, NP-C, CARN; Potter, Annie MSN, MPH, NP-C, CARN-AP; Alves, Justin RN, ACRN, CARN; Loukas, Vanessa L. MSN, FNP-C, CARN-AP; Lastimoso, Charmaine MSN, MPH, NP-C; Sodder, Shereen BA; Caputo, Andrea DNP, FNP-C, CARN-AP; LaBelle, Colleen T. MSN, RN-BC, CARN. Addiction Nursing Competencies: A Comprehensive Toolkit for the Addictions Nurse. JONA: The Journal of Nursing Administration 51(9):p 424-429, September 2021. | DOI: 10.1097/NNA.0000000000001041

With the increased role of nurses in caring for patients with substance addiction, there was a clear need to develop the Addiction Nursing Competencies to guide and support the nursing workforce. A literature search revealed a lack of formal instruments to assess and guide nurses in caring for persons with substance use disorders. The Addiction Nursing Competencies were created using existing nursing education frameworks and addiction nurse care manager clinical guidelines.

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James Harvey

ISAM Global Addiction Therapeutics Innovation Day

Shared by James Harvey (ISSUP staff) - 6 May 2025
ISAM GATID
Event Date
25 May 2025
Location:
Hamburg
Germany

We’re excited to invite you to the ISAM Global Addiction Therapeutics Innovation Day, taking place on Sunday, May 25, 2025, in Hamburg, Germany, as a pre-conference event of the 27th ISAM Annual Congress. We hope this event will serve as an...

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Rasha Abi Hana

Canadian Substance Use Costs and Harms Online Data Visualisation Tool

Shared by Rasha Abi Hana - 2 April 2025
Format
Guide
Published by / Citation
Canadian Substance Use Costs and Harms (CSUCH)

CSUCH’s data visualisation tool can be used to estimate substance use trends across the country. The data helps inform programs, practices, and research to protect communities, save lives, and improve the well-being of people in Canada.

 

Spotlight: Top 3 causes of death due to substance use in Canada 


More than 200 people died each day due to substance use (SU) in 2020 (the latest year for which data are available). That works out to 73,994 deaths that year. The average age of death due to SU was 45 years. Tobacco use caused 63% (46,366) of SU-related deaths, followed by alcohol at 23%...

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Rasha Abi Hana

Global scientific research landscape on binge drinking: a comprehensive bibliometric and visualisation analysis of trends, collaborations, and future directions

Shared by Rasha Abi Hana - 31 March 2025
Format
Scientific article
Published by / Citation
Zyoud, S.H. Global scientific research landscape on binge drinking: a comprehensive bibliometric and visualization analysis of trends, collaborations, and future directions. Subst Abuse Treat Prev Policy 20, 13 (2025). https://doi.org/10.1186/s13011-025-00641-1

Background
Binge drinking, defined as consuming five or more alcoholic drinks in a single session, is a major public health issue. It leads to cognitive and motor impairments and is linked to numerous health problems. This study aims to analyze globally published peer-reviewed literature on binge drinking.

Methods
A thorough search was conducted in the Scopus database using keywords related to binge drinking. Specific criteria were applied to filter the results, resulting in 2,763 relevant research papers. VOSviewer software was used to analyze and visualize connections between these studies...

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Rasha Abi Hana

The repeatable battery for the assessment of neuropsychological status (RBANS) and substance use disorders: a systematic review

Shared by Rasha Abi Hana - 31 March 2025
Format
Scientific article
Published by / Citation
Høiland, K., Raudeberg, R. & Egeland, J. The repeatable battery for the assessment of neuropsychological status (RBANS) and substance use disorders: a systematic review. Subst Abuse Treat Prev Policy 20, 12 (2025). https://doi.org/10.1186/s13011-025-00640-2

Background
Cognitive deficits are common in patients with substance use disorder (SUD) and can impact treatment outcomes. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is a widely used tool that could help identify cognitive impairments in SUD patients. This systematic review examines the RBANS’ effectiveness in detecting cognitive impairment in SUD patients and discusses knowledge gaps and the need for further research.

Methods
A systematic search was conducted in PsycINFO, Medline, and Cochrane databases to find relevant studies on the use of RBANS in SUD...

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Rasha Abi Hana

Perceived impacts of North Americas first de-medicalised safer supply program

Shared by Rasha Abi Hana - 31 March 2025
Format
Scientific article
Published by / Citation
Kalicum, J., Nyx, E., Kennedy, M.C. et al. Perceived impacts of North Americas first de-medicalized safer supply program. Subst Abuse Treat Prev Policy 20, 11 (2025). https://doi.org/10.1186/s13011-025-00642-0

Background
A non-medicalized safer supply model called a “Compassion Club” has recently been evaluated. The model involved providing rigorously tested and accurately labeled illicit substances to members at cost. Operating for 14 months in Vancouver's Downtown Eastside, the initiative aimed to explore the effects and feasibility of this approach among individuals at risk of fatal overdose.

Methods
At the one-year mark, 43 club members completed a survey for this cross-sectional analysis. Descriptive statistics were used to assess the perceived impact of membership on factors like drug use...

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Rasha Abi Hana

The Psychology of Addiction and Obesity: New Treatments

Shared by Rasha Abi Hana - 24 March 2025
Format
Website
Published by / Citation
Adi Zuloff-Shani Ph.D. Psychedelics to the Rescue

Addiction and obesity share similar neurological pathways, both linked to compulsive behaviors and the brain's reward system. Research has highlighted the potential of GLP-1 receptor agonists, originally developed for diabetes, to help manage both appetite and addictive cravings. These medications, such as semaglutide, may regulate addictive behaviors by influencing reward circuits in the brain. However, they come with potential side effects, and their long-term effects are still under investigation.

In addition, a new compound, 5-Methoxy-2-aminoindane (MEAI), is being researched for its...

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Rasha Abi Hana

VCU researchers are developing a long-acting medication for opioid addiction

Shared by Rasha Abi Hana - 24 March 2025
Format
News
Published by / Citation
VCU

Researchers at Virginia Commonwealth University (VCU) have developed a new version of a medication for opioid use disorder that could offer longer-lasting treatment. Current medications for opioid addiction often require daily doses, but the new formulation of nor-levo-alpha-acetylmethadol (nor-LAAM) is designed to be taken once a month or less frequently. This long-acting medication has shown promise in reducing opioid use and withdrawal symptoms in rodent models. The goal is to provide an alternative to existing treatments like methadone and buprenorphine, which come with barriers such as...

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Rasha Abi Hana

Maternal cannabis use disorder and offspring behavioral outcomes: findings from a linked data cohort study

Shared by Rasha Abi Hana - 24 March 2025
Format
Scientific article
Published by / Citation
Abay Woday Tadesse, Berihun Assefa Dachew, Getinet Ayano, Kim Betts, Rosa Alati, Maternal cannabis use disorder and offspring behavioral outcomes: findings from a linked data cohort study, Psychiatry Research, Volume 346, 2025, 116404, ISSN 0165-1781, https://doi.org/10.1016/j.psychres.2025.116404.

Few studies have looked into how cannabis use during pregnancy affects the development of disruptive behavioral disorders (DBDs) in children, often using small sample sizes and self-reported data. This study aimed to understand the link between maternal cannabis use disorder (CUD) during pregnancy and after childbirth, and the risk of DBDs in children. We used health data from New South Wales, Australia, for children born between 2003 and 2005. We compared children whose mothers had CUD to those whose mothers did not, and assessed the risk of DBDs in these children. Both CUD and DBDs were...

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Rasha Abi Hana

Overcoming barriers to traditional care delivery and pharmacy challenges: a qualitative study of buprenorphine, telehealth, and a digital therapeutic for opioid use disorder

Shared by Rasha Abi Hana - 14 March 2025
Format
Scientific article
Published by / Citation
Monico, L.B., Eastlick, M., Michero, D. et al. Overcoming barriers to traditional care delivery and pharmacy challenges: a qualitative study of buprenorphine, telehealth, and a digital therapeutic for opioid use disorder. Subst Abuse Treat Prev Policy 20, 8 (2025). https://doi.org/10.1186/s13011-024-00631-9

Background
The opioid epidemic in the U.S. contributes to increased morbidity and mortality from drug overdoses, but barriers to traditional opioid use disorder (OUD) treatment limit access to care. During the COVID-19 pandemic, Public Health Emergency (PHE) provisions relaxed in-person requirements for buprenorphine inductions, expanding telehealth options for OUD treatment. This study explores patients' experiences with a digital therapeutic telehealth program offering buprenorphine for OUD.

Methods
Semi-structured qualitative interviews were conducted with 15 participants from a larger...

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Rasha Abi Hana

Validation of the alcohol use disorders identification test in a Danish hospital setting

Shared by Rasha Abi Hana - 14 March 2025
Screening - Shutterstock image
Format
Scientific article
Published by / Citation
Schøler, P.N., Andersen, M.B., Andersen, K. et al. Validation of the alcohol use disorders identification test in a Danish hospital setting. Subst Abuse Treat Prev Policy 20, 7 (2025). https://doi.org/10.1186/s13011-025-00638-w

Background
Early identification of alcohol problems is important for timely intervention. The Alcohol Use Disorders Identification Test (AUDIT) and its shorter version, AUDIT-C, are widely used screening tools. This study tested the effectiveness of recommended AUDIT and AUDIT-C cut-off scores in a hospital setting in Denmark.

Methods
From February to April 2023, data were collected from 300 patients at Odense University Hospital. The study tested AUDIT cut-offs (≥8, ≥16, ≥20) and AUDIT-C cut-offs (≥4, ≥5) against Danish low-risk drinking guidelines and self-reported alcohol dependence...

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Rasha Abi Hana

Nonmedical Benzodiazepines in Canada

Shared by Rasha Abi Hana - 20 January 2025
CCENDU
Format
Report
Published by / Citation
CCENDU co-ordinated by the Canadian Centre on Substance Use and Addiction (CCSA)

The Canadian Community Epidemiology Network on Drug Use (CCENDU), co-ordinated by the Canadian Centre on Substance Use and Addiction (CCSA), publishes this newsletter regularly to inform people living in Canada about emerging substance use issues and trends, pulling from the best available information sources at the time of publication. 

Non-medical benzodiazepines (NMBs) are benzodiazepines and benzodiazepine-like substances that have been either illegally produced or diverted from legal sources for non-medical use. They continue to appear in the unregulated drug supply, increasing risks to...

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James Harvey

Alcohol Use Disorder Treatment: Problems and Solutions

Shared by James Harvey (ISSUP staff) - 7 January 2025
Alcohol Use Disorder Treatment: Problems and Solutions.
Format
Scientific article
Published by / Citation
George F. Koob, Annual Review of Pharmacology and Toxicology, Volume 64, 2024, pp. 255-275
This review outlines challenges that face the alcohol field in closing this treatment gap and offers solutions, including broadening end points for the approval of medications for the treatment of AUD
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Rasha Abi Hana

Prevalence of Anti-Social Behavior Among Women with Substance Use Disorder in Pakistan

Shared by Rasha Abi Hana - 28 November 2024
Format
Scientific article
Published by / Citation
Saddiqua, A., & Zunnurain, M. Z. (2024). Prevalence of antisocial behavior among women with substance use disorder in Pakistan. Adiktologie, 24(2), 81–87. https://doi.org/10.35198/01-2024-002-0004

INTRODUCTION: Pakistan is ominously impacted by the menace of substance abuse. Women, who represent 42% of the total population, are primarily affected by the use of illicit substances with co-occurring behavioural disorders. Despite extensive efforts, prevalence estimates reported here are likely to underestimate substance use among women. A high level of dependency was observed among the cases who were reported; however, the unreported cases in the general population are beyond the count. This study focuses on an approximation about the prevalence of anti-social behaviour among women in...

AddictologyIssue 2/2024
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Rasha Abi Hana

Power of Collaboration: ISSUP and GWN Highlight Critical Gaps in Women’s SUD Treatment

Shared by Rasha Abi Hana - 28 November 2024
ISSUP and GWN

The Power of Collaboration project, a joint initiative between ISSUP and the Global Women's Network (GWN), explores critical areas in the treatment of substance use disorders (SUD) for women. Through the collaboration between ISSUP, which commits to improving the effectiveness of the substance use treatment and recovery workforce, and the Global Women’s Network (GWN), which works to increase the availability of high-quality, gender-responsive treatment for women, the Power of Collaboration project has provided valuable insights into the challenges women face in accessing SUD treatment and the...

Translations
Português
Indonesian
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Rasha Abi Hana

ISSUP at Lisbon Addictions 2024: Empowering the Workforce of the Future

Shared by Rasha Abi Hana - 5 November 2024
Learning from Africa: Workforce Development, Enhancement, and Support Session at Lisbon Addictions.

From October 23rd to 25th, 2024, Lisbon hosted the Lisbon Addictions 2024 Conference, bringing together 2,231 participants from around the world. The event provided a dynamic platform for sharing the latest research in addiction science and exploring future directions in addiction policy and practice. The Conference theme, "Empowering the Workforce of the Future," focused on strengthening the workforce in addiction prevention, treatment, and recovery, underscoring the critical need for well-trained professionals to meet the evolving demands of the field.

ISSUP actively participated in the...

Translations
Français
العربية
Turkish
Vietnamese
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Hala Najm

Development of a Personalized Feedback Intervention Targeting Pain-Related Anxiety for Adults Reporting Hazardous Drinking and Chronic Pain: A Randomized Controlled Trial

Shared by Hala Najm - 28 October 2024
Format
Scientific article
Published by / Citation
Journal of Studies on Alcohol and Drugs

Individuals with chronic pain are more likely to engage in hazardous alcohol use compared to the general population. Despite this increased risk, they are an underserved group regarding targeted interventions. There is a pressing need to explore and develop alternative strategies to effectively reduce hazardous drinking in this vulnerable population. One promising approach is to focus on managing pain-related anxiety, which is a potential mechanism linked to hazardous drinking.

Researchers adopted a phased model (1A/1B) to address this need to create and test a new personalized feedback...

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Hala Najm

Seasonal Variations in Treatment Seeking for Alcohol Use Disorder in the Total Danish Population

Shared by Hala Najm - 28 October 2024
Format
Scientific article
Published by / Citation
Journal of Studies on Alcohol and Drugs

A significant number of individuals with alcohol use disorder (AUD) do not seek treatment, and the factors influencing treatment-seeking behavior are not well understood. While it is known that alcohol consumption levels can fluctuate with the seasons, the impact of these seasonal changes on seeking treatment for AUD remains unclear. This study aimed to explore whether there are seasonal patterns in the pursuit of treatment for AUD.

To investigate this, researchers conducted a time-series analysis involving adults in Denmark aged 18 and older who sought treatment for AUD. They focused on two...

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Marisol Sepulveda Gómez

Uso de los manuales de intervención

Marisol Sepulveda Gómez - 31 Agosto 2024

El uso de manuales permite estandarizar intervenciones que se realizan a los usuarios, teniendo unos parámetros que permiten guiar a los usuarios en busca de su bienestar. Sin embargo, estos debe tener la capacidad de flexibilizarlo con el fin de tener en cuenta las particularidades de los casos y ser ajustados a los modelos de atención en salud, ya que estos pueden funcionar pero si los profesionales que atienden no tienen el suficiente tiempo para aplicarse se va a generar una renuencia al realizarse. Por ejemplo en Colombia nuestros profesionales de la salud tienen 20 minutos para realizar...

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