Genetics

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Source: https://www.nature.com/articles/s44220-023-00034-y Abstract Genetic liability to substance use disorders can be parsed into loci that confer general or substance-specific addiction risk. We report a multivariate genome-wide association meta-analysis that disaggregates general and substance...

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Source: Bohnsack, J. P., Zhang, H., Wandling, G. M., He, D., Kyzar, E. J., Lasek, A. W., & Pandey, S. C. (2022). Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure. Science advances, 8(18), eabn2748. Abstract Adolescent binge drinking is a...

Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure.pdf

Source: Pasman, J. A., Verweij, K., Gerring, Z., Stringer, S., Sanchez-Roige, S., Treur, J. L., Abdellaoui, A., Nivard, M. G., Baselmans, B., Ong, J. S., Ip, H. F., van der Zee, M. D., Bartels, M., Day, F. R., Fontanillas, P., Elson, S. L., 23andMe Research Team, de Wit, H., Davis, L. K., MacKillop...

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Fuente: Marín-Navarrete, R., Templos-Núñez, L., & Nicolini, H. (2022). Reflexiones sobre epigenética, confinamiento, violencia y estrés en niños, niñas y adolescentes durante la pandemia por COVID-19. Revista inteRnacional de investigación en adicciones, 8(2), 3-6. Los últimos dos años han...

Reflexiones sobre epigenética, confinamiento, violencia y estrés en niños, niñas y adolescentes durante la pandemia por COVID-19.pdf

¿Cuántos genes influyen para que una persona desarrolle una adicción? ¿Sabemos cuáles son estos genes? ¿Existen genes que determinan la adicción a ciertas substancias? Estas y otras preguntas serán respondidas por la Dra. Alejandra Ruiz, investigadora de la UNAM.

Source: Sánchez Huesca R, Templos Núñez LB. A look at genetics and epigenetics in substance addiction. RIIAD [Internet]. 2022 Mar. 29 [cited 2022 Mar. 29];8(1):51-6. Available from: https://riiad.org/index.php/riiad/article/view/riiad-2022-1-06 Resumen Los trastornos por consumo de sustancias...

Una mirada a la genética y epigenética en adicción a sustancias.pdf

Source: Joo YY, Moon S, Wang H, et al. Association of Genome-Wide Polygenic Scores for Multiple Psychiatric and Common Traits in Preadolescent Youths at Risk of Suicide. JAMA Netw Open. 2022;5(2):e2148585. doi:10.1001/jamanetworkopen.2021.48585 Key Points Question Are genome-wide polygenic scores...

Association of Genome-Wide Polygenic Scores for Multiple Psychiatric and Common Traits in Preadolescent Youths at Risk of Suicide.pdf

Source: Ortega-Mora, E. I., Caballero-Sánchez, U., Román-López, T. V., Rosas-Escobar, C. B., González-Barrios, J. A., Romero-Hidalgo, S., ... & Ruiz-Contreras, A. E. (2021). Allele-dosage genetic polymorphisms of cannabinoid receptor 1 predict attention, but not working memory performance in humans...

Allele-dosage genetic polymorphisms of cannabinoid receptor 1 predict attention, but not working memory performance in humans.pdf

Humberto Nicolini, INMEGEN María Elena Medina-Mora, Facultad de Psicología, UNAM Jorge Ameth Villatoro Velázquez, Instituto Nacional de Psiquiatría "Ramón de la Fuente Muñiz" Marycarmen Noemí Bustos Gamiño, Instituto Nacional de Psiquiatría "Ramón de la Fuente Muñiz"

Source: Vink, J. M., Veul, L., Abdellaoui, A., Hottenga, J. J., Boomsma, D. I., & Verweij, K. J. (2020). Illicit Drug Use and the Genetic Overlap with Cannabis Use. Drug and Alcohol Dependence, 108102. Highlights •Lifetime prevalence: cannabis 24.8 %. •ecstacy 6.2 %, stimulants 6.5 % and any illicit...

Illicit drug use and the genetic overlap with Cannabis use.pdf

Source: Pasman, J., Smit, D., Kingma, L., Vink, J., Treur, J., & Verweij, K. (2020, July 02). Causal relationships between substance use and insomnia. Retrieved from https://www.sciencedirect.com/science/article/pii/S0376871620303161 Highlights •Insomnia and substance use have been linked, but the...

Causal relationships between substance use and insomnia_0.pdf

Fuente: Ruiz Contreras, A., Méndez Díaz, M., Prieto Gómez, B., Romano, A., Caynas, S., & Prospéro García, O. (2010). El cerebro, las drogas y los genes. Salud Mental, 33(6), 535-542. Resumen En este segundo artículo sobre el tema reseñamos brevemente las drogas de abuso ilícitas. Describiremos...

El cerebro, las drogas y los genes.pdf

Source: Vicky Ping Chen, Yang Gao, Liyi Geng, Mike Steele, Nathan Jenks, Kah-Whye Peng, and Stephen Brimijoin.Human Gene Therapy.ahead of printhttp://doi.org/10.1089/hum.2019.233 Abstract Cocaine addiction continues to impose major burdens on affected individuals and broader society but is highly...

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Source: Jung Y, Montel RA, Shen P, Mash DC, Goldman D. Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders: A Systematic Review and Meta-analysis. JAMA Netw Open. 2019;2(11):e1914940. doi:https://doi.org/10.1001/jamanetworkopen.2019...

Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders A Systematic Review and Meta-analysis_1.pdf

Recent advances in DNA analysis are helping researchers untangle complex genetic interactions by examining a person's entire genome all at once. Technologies such as genome-wide association studies (GWAS)

genetics_and_epigenetics_drugfacts_2.pdf

Conferencia transmitida el día 12 de octubre de 2018. Los avances en la Genómica nos permiten atacar el entendimiento de diferentes conductas desde el nivel molecular. En esta conferencia veremos lo que ha descubierto la ciencia sobre las bases genéticas de los procesos mentales y cómo esto nos...

Source: Arcos-Burgos, M., Vélez, J. I., Martinez, A. F., Ribasés, M., Ramos-Quiroga, J. A., Sánchez-Mora, C., ... & Casas, M. (2019). ADGRL3 (LPHN3) variants predict substance use disorder. Translational psychiatry, 9(1), 42. Abstract Genetic factors are strongly implicated in the susceptibility to...

ADGRL3 (LPHN3) variants predict substance use disorder.pdf

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Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia

Reflexiones sobre epigenética, confinamiento, violencia y estrés en niños, niñas y adolescentes durante la pandemia por COVID-19

Factores genéticos y adicciones - Dra. Alejandra Ruíz

Una mirada a la genética y epigenética en adicción a sustancias

Association of Genome-Wide Polygenic Scores for Multiple Psychiatric and Common Traits in Preadolescent Youths at Risk of Suicide

Allele-dosage genetic polymorphisms of cannabinoid receptor 1 predict attention, but not working memory performance in humans

Seminario de Investigación | Avances del proyecto ENCODAT-INMEGEN, de la epidemiología a la genómica

Background:

Illicit drug use and the genetic overlap with Cannabis use

Causal relationships between substance use and insomnia

El cerebro, las drogas y los genes

Systemic Safety of a Recombinant AAV8 Vector for Human Cocaine Hydrolase Gene Therapy: A Good Laboratory Practice Preclinical Study in Mice

Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders A Systematic Review and Meta-analysis

Genetics and Epigenetics of Addiction

La vulnerabilidad genética al suicidio

Summary

Background

Abstract

ADGRL3 (LPHN3) variants predict substance use disorder

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